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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

The biotechnological potential of Epicoccum spp.: diversity of secondary metabolites

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Braga, Raissa Mesquita [1] ; Padilla, Gabriel [1] ; Araujo, Welington Luiz [1]
Total Authors: 3
[1] Univ Sao Paulo, Inst Biomed Sci, Dept Microbiol, NAP BIOP LABMEM, Av Prof Lineu Prestes, 1374 Ed Biomed 2, BR-05508900 Sao Paulo, SP - Brazil
Total Affiliations: 1
Document type: Review article
Source: CRITICAL REVIEWS IN MICROBIOLOGY; v. 44, n. 6, p. 759-778, 2018.
Web of Science Citations: 1

Epicoccum is a genus of ubiquitous fungi typically found in air, in soil, and on decaying vegetation. They also commonly display an endophytic lifestyle and are isolated from diverse plant tissues. The fungi from the genus Epicoccum are mainly known for their use as biocontrol agents against phytopathogens and for their ability to produce many secondary metabolites with potential biotechnological applications, such as antioxidant, anticancer, r and antimicrobial compounds. Among the bioactive compounds produced by Epicoccum spp., epicocconone is a commercially available fluorophore, D8646-2-6 is a patented telomerase inhibitor, and taxol is an anticancer drug originally isolated from Taxus brevifolia. Epicoccum spp. also produces epicolactone, an antimicrobial compound with a unique and complex structure that has aroused considerable interest in the chemical-synthesis community. The main goal of the present review is to discuss the diversity of secondary metabolites produced by Epicoccum spp., their biotechnological applications, and proposed hypothetical biosynthesis. In addition, the use of Epicoccum spp. as biocontrol agents and the pigments produced by these fungi are also discussed. (AU)

FAPESP's process: 17/12510-4 - Endophytic microorganisms and the host plant: genes and metabolites involved in the interaction
Grantee:Welington Luiz de Araújo
Support type: Regular Research Grants
FAPESP's process: 15/11563-1 - Molecular mechanisms related to the interaction between endophytic microorganisms and the host plant
Grantee:Welington Luiz de Araújo
Support type: Regular Research Grants