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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Effects of dietary thyme essential oil on hemato-immunological indices, intestinal morphology, and microbiota of Nile tilapia

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Author(s):
Ramos Valladao, Gustavo Moraes [1] ; Gallani, Silvia Umeda [2] ; Kotzent, Suzana [3] ; Assane, Inacio Mateus [2] ; Pilarski, Fabiana [2, 3]
Total Authors: 5
Affiliation:
[1] Univ Nilton Lins, Postgrad Program Aquaculture, BR-69058 Manaus, Amazonas - Brazil
[2] Univ Estadual Paulista, CAUNESP, Aquaculture Ctr, Microbiol & Parasitol Lab, BR-14870 Jaboticabal, SP - Brazil
[3] Univ Estadual Paulista, UNESP, Dept Agr Microbiol, BR-14870 Jaboticabal, SP - Brazil
Total Affiliations: 3
Document type: Journal article
Source: AQUACULTURE INTERNATIONAL; v. 27, n. 2, p. 399-411, APR 2019.
Web of Science Citations: 3
Abstract

Thyme (Thymus vulgaris) essential oil (TVEO) is a herbal medicine with one of the highest levels of antimicrobial activity. Although TVEO has been broadly used in poultry and swine production due to its immunostimulatory and growth-promoting characteristics, the effects of TVEO on fish are poorly characterized. In this study, Nile tilapia (Oreochromis niloticus L.) were fed 0, 0.1, 0.5, and 1% TVEO for 15days. Subsequently, blood parameters, intestinal morphology, and the population of Bacillus bacteria in the intestine were evaluated. The numbers of lymphocytes (p<0.05) and leukocytes (p<0.05) significantly increased in the blood of the fish fed the highest dose of TVEO. Based on the normal behavior of the fish and the alanine aminotransferase (ALT) and aspartate aminotransferase (AST) levels, which were not altered (p>0.05), this study concluded that the diets were safe and showed no negative or toxic effects. Even at doses as high as 1%, TVEO did not alter the population of beneficial Bacillus bacteria in the gut. In conclusion, supplementation with TVEO stimulated the cellular components of the non-specific immune response of Nile tilapia without causing deleterious effects or altering the population of important intestinal bacteria. (AU)

FAPESP's process: 14/14039-9 - Phytotherapics in diets for fish: molecular characterization of the microbiota, morphology and study of molecules associated with gut health
Grantee:Gustavo Moraes Ramos Valladão
Support type: Scholarships in Brazil - Doctorate