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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Discovery of novel astrovirus and calicivirus identified in ruddy turnstones in Brazil

Full text
Author(s):
de Souza, William Marciel [1, 2, 3] ; Fumagalli, Marcilio Jorge [1] ; de Araujo, Jansen [4] ; Ometto, Tatiana [4] ; Modha, Sejal [2] ; Thomazelli, Luciano Matsumiya [4] ; Durigon, Edison Luis [4] ; Murcia, Pablo Ramiro [2] ; Moraes Figueiredo, Luiz Tadeu [1]
Total Authors: 9
Affiliation:
[1] Univ Sao Paulo, Virol Res Ctr, Sch Med Ribeirao Preto, BR-14049900 Ribeirao Preto, SP - Brazil
[2] Univ Glasgow, MRC, Ctr Virus Res, Glasgow G61 1QH, Lanark - Scotland
[3] Univ Estadual Campinas, Inst Biol, Dept Genet Evolut & Bioagents, BR-13083862 Campinas, SP - Brazil
[4] Univ Sao Paulo, Inst Biomed Sci, BR-05508900 Sao Paulo, SP - Brazil
Total Affiliations: 4
Document type: Journal article
Source: SCIENTIFIC REPORTS; v. 9, APR 3 2019.
Web of Science Citations: 1
Abstract

Birds are the natural reservoir of viruses with zoonotic potential, as well as contributing to the evolution, emergence, and dissemination of novel viruses. In this study, we applied a high-throughput screening approach to identify the diversity of viruses in 118 samples of birds captured between October 2006 to October 2010 in the North and Northeast regions of Brazil. We found nearly complete genomes of novel species of astrovirus and calicivirus in cloacal swabs of ruddy turnstones (Arenaria interpres) collected in Coroa do Aviao islet, Pernambuco State. These viruses are positive-sense single-stranded RNA with a genome of -7 to 8 kb, and were designated as Ruddy turnstone astrovirus (RtAstV) and Ruddy turnstone calicivirus (RTCV), respectively. Phylogenetic analysis showed that RtAstV and RTCV grouped in a monophyletic clade with viruses identified from poultry samples (i.e., chicken, goose, and turkey), including viruses associated with acute nephritis in chickens. Attempts of viral propagation in monkey and chicken cell lines for both viruses were unsuccessful. Also, we found genomes related with viral families that infect invertebrates and plants, suggesting that they might be ingested in the birds' diet. In sum, these findings shed new light on the diversity of viruses in migratory birds with the notable characterization of a novel astrovirus and calicivirus. (AU)

FAPESP's process: 12/24150-9 - Research of virus in wild rodents, mosquitoes and ticks
Grantee:William Marciel de Souza
Support type: Scholarships in Brazil - Doctorate
FAPESP's process: 17/13981-0 - Characterization, genomics and diagnostic of viruses with importance for public health in Brazil by high throughput sequencing
Grantee:William Marciel de Souza
Support type: Scholarships in Brazil - Post-Doctorate
FAPESP's process: 16/01414-1 - Production of recombinant viral antigenic peptides and development of methods for serological diagnosis of infections by Chikungunya, Mayaro and Zika viruses
Grantee:Marcilio Jorge Fumagalli
Support type: Scholarships in Brazil - Master
FAPESP's process: 13/05485-2 - Study of Newcastle disease virus by real-time RT-PCR method in wild birds from different regions of Brazil and the Antarctic
Grantee:Luciano Matsumiya Thomazelli
Support type: Regular Research Grants
FAPESP's process: 13/14929-1 - Detection of arbovirus and other RNA viruses by real time RT-PCR and study of the viroma
Grantee:Luiz Tadeu Moraes Figueiredo
Support type: Regular Research Grants
FAPESP's process: 11/13821-7 - Comparative eco-epidemiology of Avian Influenza virus in migratory birds in Brazilian territory
Grantee:Jansen de Araujo
Support type: Scholarships in Brazil - Post-Doctorate
FAPESP's process: 18/09383-3 - Study about Flavivirus epitopes with medical importance in Brazil and its antibodies
Grantee:Marcilio Jorge Fumagalli
Support type: Scholarships in Brazil - Doctorate
FAPESP's process: 09/05994-9 - Surveillance of West Nile Virus in Brazil
Grantee:Tatiana Ometto de Araujo
Support type: Scholarships in Brazil - Doctorate (Direct)
FAPESP's process: 15/05778-5 - Bioinformatics analysis of data of viral metagenomic of animals from Brazil and Antarctica
Grantee:William Marciel de Souza
Support type: Scholarships abroad - Research Internship - Doctorate