| Full text | |
| Author(s): Show less - |
Paula Durante Andrade
[1]
;
Joice de Souza Russo
[2]
;
Jéssica Baliero Gouveia
[3]
;
Cláudia Raquel Cantarelli Costa
[4]
;
Ketti Gleyzer Oliveira
[5]
;
Michelli Gianetti
[6]
;
Emanuel Borges Vítor Anjos
[7]
;
Tycha Bianca Sabaini Pavan
[8]
;
Mariana Furquim Da Silva Martins
[9]
;
Josiele Franco
[10]
;
Maria Laura Costa
[11]
;
Marcelo Luís Nomura
[12]
;
Carlos Emílio Levy
[13]
;
Renato Passini Júnior
[14]
;
Sandra Cecilia Botelho Costa
[15]
Total Authors: 15
|
| Affiliation: Show less - | [1] State University of Campinas. Faculty of Medical Sciences. Department of Clinical Medicine - Brasil
[2] State University of Campinas. Faculty of Medical Sciences. Department of Clinical Medicine - Brasil
[3] State University of Campinas. Faculty of Medical Sciences. Department of Clinical Medicine - Brasil
[4] State University of Campinas. Faculty of Medical Sciences. Department of Clinical Medicine - Brasil
[5] State University of Campinas. Faculty of Medical Sciences. Department of Clinical Medicine - Brasil
[6] State University of Campinas. Faculty of Medical Sciences. Department of Clinical Medicine - Brasil
[7] State University of Campinas. Faculty of Medical Sciences. Department of Clinical Medicine - Brasil
[8] State University of Campinas. Faculty of Medical Sciences. Department of Clinical Medicine - Brasil
[9] State University of Campinas. Faculty of Medical Sciences. Department of Clinical Medicine - Brasil
[10] State University of Campinas. Faculty of Medical Sciences. Department of Clinical Medicine - Brasil
[11] State University of Campinas. Faculty of Medical Sciences. Department of Obstetrics and Gynecology - Brasil
[12] State University of Campinas. Faculty of Medical Sciences. Department of Obstetrics and Gynecology - Brasil
[13] State University of Campinas. Faculty of Medical Sciences. Department of Clinical Pathology - Brasil
[14] State University of Campinas. Faculty of Medical Sciences. Department of Obstetrics and Gynecology - Brasil
[15] State University of Campinas. Faculty of Medical Sciences. Department of Clinical Medicine - Brasil
Total Affiliations: 15
|
| Document type: | Journal article |
| Source: | MedicalExpress (São Paulo, online); v. 4, n. 4 2017-08-00. |
| Abstract | |
OBJECTIVE: Group B Streptococcus (GBS) serotypes (Ia, Ib and II to IX) are classified based on variations in their capsular polysaccharide; their prevalence differs between different geographic areas. We examined the prevalence of all GBS serotypes in rectal and vaginal swab samples obtained from 363 pregnant women followed at a Brazilian referral center (Hospital da Mulher Professor Doutor José Aristodemo Pinotti); bacterial susceptibility to antibiotics was further determined. METHOD: Prevalence of positive GBS was evaluated by latex agglutination and by multiplex PCR analysis; bacterial susceptibility to antibiotics, such as clindamycin, erythromycin, levofloxacin, linezolid, penicillin and tetracycline was determined by the disk diffusion method. RESULTS: (a) standard GBS culture and the multiplex PCR analysis tested positive for 83 swabs, collected from 72 women (prevalence of GBS colonization: 72/363; 20%); the most prevalent Serotype was Ia (n=43/83; 52%), followed by serotype V (n=14/83; 17%); according to anatomical origin, serotype Ia accounted for 27/59 (46%) and 16/24 (67%) of the vaginal and rectal samples, respectively; PCR also identified serotypes Ib, II, III and VI. Serotype VI is rarely described and had not been previously reported in Brazil or in Latin America. (b) The latex agglutination test only identified 44 positive samples, all of which were serotyped: 34 of these samples (77%) had serotypes matching those identified by multiplex PCR. (c) Only one sample (serotype Ia) showed resistance to erythromycin and clindamycin. CONCLUSION: Regional studies on GBS serotypes prevalence are essential to guide immunoprophylactic interventions (vaccines) and the implementation of adequate antibiotic prophylaxis or treatment. In this study, the incidence of the serotype VI, a new and rare serotype of GBS was described for the first time in a Brazilian population. (AU) | |
| FAPESP's process: | 10/50061-8 - Comparative study between standard culture in selective media and Real Time Polymerase Chain Reaction assay for detection of maternal colonization by group B Streptococcus |
| Grantee: | Sandra Cecília Botelho Costa |
| Support Opportunities: | Regular Research Grants |