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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

The relationship between heart rate and VO2 in moderate-to-severe asthmatics

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Rodrigues Mendes, Felipe A. [1, 2] ; Teixeira, Renata Nakata [3] ; Martins, Milton A. [4] ; Cukier, Alberto [5] ; Stelmach, Rafael [5] ; Medeiros, Wladimir Musetti [2] ; Carvalho, Celso R. F. [1]
Total Authors: 7
[1] Univ Sao Paulo, Dept Phys Therapy, Sao Paulo - Brazil
[2] Univ Ibirapuera, Dept Phys Therapy, Sao Paulo - Brazil
[3] Univ Sao Paulo, Dept Clin Immunol & Allergy, Sao Paulo - Brazil
[4] Univ Sao Paulo, Sch Med, Dept Med, Av Dr Arnaldo, 455 Room, Sao Paulo - Brazil
[5] Univ Sao Paulo, Clin Hosp, Sch Med, Heart Inst Incor, Sao Paulo - Brazil
Total Affiliations: 5
Document type: Journal article
Web of Science Citations: 0

Objective: The main purpose of this study was to evaluate whether the %HRR-%VO2R relationship and %HRR-VO2peak relationship are affected in patients with moderate or severe asthma and whether airway obstruction and aerobic capacity influence these relationships. Methods: A linear regression was calculated using the paired %VO2R-%HRR and %VO2peak-%HRR for 93 subjects with asthma. The mean slope and y-intercept were calculated and compared with the line of identity (y-intercept = 0, slope = 1) for all patients and subgroups for the following conditions: low and normal VO2peak and low and normal FEV1. Results: The slope and intercepts of %VO2R-%HRR were similar to the line of identity for all groups (p > 0.05), and the regressions between %HRR and %VO2peak did not coincide with the line of identity for all groups (p < 0.05). There were no associations between the intercepts of the %HRR-VO2peak and the %HRR-%VO2R relationship with the VO2peak (p > 0.05) or FEV1 (p > 0.05). Conclusions: This is the first study to confirm a constant equivalence between %HRR and %VO2R in outpatients with moderate or severe asthma. Our data also suggest that the relationship between %HRR and %VO2peak is unreliable. These results support the use of %HRR in relation to %VO2R to estimate exercise intensity in this population, independently of the pulmonary function and fitness level. (AU)

FAPESP's process: 09/53904-9 - Effects of environment and lifestyle on asthma and chronic obstructive pulmonary disease: studies with experimental animals and people with asthma
Grantee:Milton de Arruda Martins
Support type: Research Projects - Thematic Grants