| Full text | |
| Author(s): |
Souto, Denio E. P.
[1]
;
Volpe, Jaqueline
[1]
;
Goncalves, Conrado de C.
[2]
;
Ramos, I, Carlos H.
;
Kubota, Lauro T.
[3, 4]
Total Authors: 5
|
| Affiliation: | [1] Fed Univ Parana UPPE, Dept Chem, BR-81530900 Curitiba, Parana - Brazil
[2] Univ Estadual Campinas, UNICAMP, Inst Chem, BR-13083970 Campinas, SP - Brazil
[3] Ramos, Carlos H., I, Univ Estadual Campinas, UNICAMP, Inst Chem, BR-13083970 Campinas, SP - Brazil
[4] Natl Inst Sci & Technol Bioanalyt INCTBio, Rio De Janeiro, RJ - Brazil
Total Affiliations: 4
|
| Document type: | Review article |
| Source: | Talanta; v. 205, DEC 1 2019. |
| Web of Science Citations: | 1 |
| Abstract | |
The phenomenon of surface plasmon resonance (SPR) through optical sensors was developed from initial studies involving excitation of surface plasmons on metallic substrates. From the beginning, these optical systems have attracted increasing interest for application in different areas, ranging from physics, chemistry, and materials science to biology. Although numerous applications have been explored, the use of SPR in the development of biosensors is by far the most prominent. This review provides a brief account of fundamental aspects related to the recent applications of SPR as a tool for the development of new clinical diagnosis methods. The applications of SPR biosensors were illustrated through recent studies published in the field of neglected tropical diseases, with an emphasis on the contributions achieved in visceral leishmaniasis. It was possible to demonstrate the real benefits and the difficulties that the SPR biosensors have encountered in this important and complex system. Finally, future trends in the use of nanomaterials for the development of SPR-based portable devices for application to neglected tropical diseases have been demonstrated. (AU) | |
| FAPESP's process: | 17/26131-5 - The chaperome: study of the relationship of the structure of its components and the maintenance of proteostasis |
| Grantee: | Carlos Henrique Inacio Ramos |
| Support Opportunities: | Research Projects - Thematic Grants |
| FAPESP's process: | 17/26058-6 - Characterization of interactions in the protein quality system for the understanding of its role in the proteostasis maintenance |
| Grantee: | Dênio Emanuel Pires Souto |
| Support Opportunities: | Scholarships in Brazil - Post-Doctoral |
| FAPESP's process: | 14/50867-3 - INCT 2014: National Institute of Science and Technology in Bioanalysis |
| Grantee: | Marco Aurelio Zezzi Arruda |
| Support Opportunities: | Research Projects - Thematic Grants |
| FAPESP's process: | 13/22127-2 - Development of novel materials strategic for integrated analytical devices |
| Grantee: | Lauro Tatsuo Kubota |
| Support Opportunities: | Research Projects - Thematic Grants |