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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Osteoporosis evaluation through full developed speckle imaging

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Amaral, Marcello Magri [1] ; del-Valle, Matheus [2, 3] ; Raele, Marcus Paulo [2] ; De Pretto, Lucas Ramos [2] ; Ana, Patricia Aparecida [3]
Total Authors: 5
[1] Univ Brazil, Inst Cient & Tecnol, Rua Carolina Fonseca 235, BR-05508000 Sao Paulo - Brazil
[2] CNEN SP, IPEN, Sao Paulo - Brazil
[3] Fed Univ ABC, Ctr Engn Modeling & Appl Social Sci, Sao Bernardo Do Campo - Brazil
Total Affiliations: 3
Document type: Journal article
Source: Journal of Biophotonics; v. 13, n. 7 APR 2020.
Web of Science Citations: 0

Osteoporosis is a disease characterized by bone mineral density reduction, weakening the bone structure. Its diagnosis is performed using ionizing radiation, increasing health risk. Optical techniques are safer, due to non-ionizing radiation use, but limited to the analyses of bone tissue. This limitation may be circumvented in the oral cavity. In this work we explored the use of laser speckle imaging (LSI) to differentiate the sound and osteoporotic maxilla and mandible bones in an in vitro model. Osteoporosis lesions were simulated with acid attack. The samples were evaluated by optical profilometry and LSI, using a custom software. Two image parameters were evaluated, speckle contrast ration and patches ratio. With the speckle contrast ratio, it was possible to differentiate sound from osteoporotic tissue. From speckle patches ratio it was observed a negative correlation with the roughness parameter. LSI is a promissory technique for assessment of osteoporosis lesions on alveolar bone. (AU)

FAPESP's process: 17/21887-4 - Analysis and modeling of the thermal, optical and mechanical behavior of healthy and demineralized oral tissues during radiotherapy submitted to high-intensity short-pulsed laser irradiation associated or not with bioactive materials
Grantee:Patricia Aparecida da Ana
Support Opportunities: Regular Research Grants
FAPESP's process: 17/21851-0 - Development of optical coherence tomography (OCT) imaging and signal analysis methodologies for the evaluation of cutaneous angiogenesis
Grantee:Marcello Magri Amaral
Support Opportunities: Regular Research Grants