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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Preserved executive functioning and low stress symptoms in children treated for acute lymphoblastic leukemia

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Gomes Godoy, Priscilla Brandi [1] ; de Mello, Claudia Berlim [1] ; Pompeia, Sabine [1] ; Lima da Costa, Cecilia Maria [2] ; Cypriano, Monica dos Santos [3] ; Suchecki, Deborah [1]
Total Authors: 6
[1] Univ Fed Sao Paulo, Dept Psicobiol, Escola Paulista Med, 925 Napoleao de Barros St 1st Floor, BR-04023062 Sao Paulo - Brazil
[2] Fundacao Antonio Prudente, AC Camargo Canc Ctr, Sao Paulo - Brazil
[3] Grp Apoio Ao Adolescente & Crianca Com Canc GRAAC, Inst Oncol Pediat, Sao Paulo - Brazil
Total Affiliations: 3
Document type: Journal article
Web of Science Citations: 0

Pediatric cancer treatment can negatively impact cognitive and psychosocial development, although it has been suggested that these adverse effects may be minimized when children have higher resilience and better executive functioning. We aimed to evaluate the impact of pediatric Acute Lymphoblastic Leukemia (ALL) treatment on executive function, resilience and stress in survivors and to investigate correlations between executive functioning and resilience and between executive functioning and stress. The neuropsychological assessment was performed in 32 ALL survivors aged 7-17 years and 28 age-, sex- and socioeconomic status matched controls. Executive functioning was assessed by inhibitory control, mental flexibility and working memory tasks. Children's self-report scales were used to assess stress symptoms and resilience. Results revealed no executive function impairment nor stress symptom differences between ALL survivors and control group. In the ALL group, executive function and resilience were positively correlated, whereas executive function and stress were negatively correlated. We concluded that ALL treatment was not associated with impairment in executive functioning nor to increased stress symptoms in our sample. ALL survivors with better performance in mental flexibility and inhibition tasks reported fewer stress symptoms and more resilience, indicating a possible relationship between these variables. (AU)

FAPESP's process: 17/04483-7 - Depression, anxiety and executive functions in pediatric patients after acute leukemia treatment: a comparative study with siblings
Grantee:Priscilla Brandi Gomes Godoy
Support type: Scholarships in Brazil - Master