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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

How can nanotechnology help to combat COVID-19? Opportunities and urgent need

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Author(s):
Campos, Estefania V. R. [1] ; Pereira, Anderson E. S. [2] ; de Oliveira, Jhones Luiz [2] ; Carvalho, Lucas Braganca [2] ; Guilger-Casagrande, Mariana [3] ; de Lima, Renata [3] ; Fraceto, Leonardo Fernandes [2]
Total Authors: 7
Affiliation:
[1] Fed Univ ABC, Human & Nat Sci Ctr, Ave Estados, 5001 Bl A, T3 Lab 503-3 Bangu, Santo Andre, SP - Brazil
[2] Sao Paulo State Univ UNESP, Inst Sci & Technol, Sorocaba, SP - Brazil
[3] Univ Sorocaba, Rodovia Raposo Tavares Km 92, 5, Sorocaba, SP - Brazil
Total Affiliations: 3
Document type: Review article
Source: JOURNAL OF NANOBIOTECHNOLOGY; v. 18, n. 1 SEP 5 2020.
Web of Science Citations: 0
Abstract

Incidents of viral outbreaks have increased at an alarming rate over the past decades. The most recent human coronavirus known as COVID-19 (SARS-CoV-2) has already spread around the world and shown R(0)values from 2.2 to 2.68. However, the ratio between mortality and number of infections seems to be lower in this case in comparison to other human coronaviruses (such as severe acute respiratory syndrome coronavirus (SARS-CoV) and Middle East respiratory syndrome coronavirus (MERS-CoV)). These outbreaks have tested the limits of healthcare systems and have posed serious questions about management using conventional therapies and diagnostic tools. In this regard, the use of nanotechnology offers new opportunities for the development of novel strategies in terms of prevention, diagnosis and treatment of COVID-19 and other viral infections. In this review, we discuss the use of nanotechnology for COVID-19 virus management by the development of nano-based materials, such as disinfectants, personal protective equipment, diagnostic systems and nanocarrier systems, for treatments and vaccine development, as well as the challenges and drawbacks that need addressing. (AU)

FAPESP's process: 17/24402-1 - pH AND TEMPERATURE SENSITIVE DRUG NANOCARRIERS FOR SKIN APPLICATIONS
Grantee:Estefânia Vangelie Ramos Campos
Support type: Scholarships in Brazil - Post-Doctorate
FAPESP's process: 19/05100-0 - EVALUATION OF THE BIOLOGICAL ACTIVITY OF TOPICAL FORMULATIONS OF BUDESONIDE IN INFLAMMATORY SKIN MODELS
Grantee:Estefânia Vangelie Ramos Campos
Support type: Scholarships abroad - Research Internship - Post-doctor
FAPESP's process: 18/23608-8 - Development of labelled nanopesticides aiming studies of mechanism of action and toxicity
Grantee:Lucas Bragança de Carvalho
Support type: Scholarships in Brazil - Post-Doctorate
FAPESP's process: 17/21004-5 - Agriculture, micro/nanotechnology and environment: from evaluation of the mechanisms of action to studies of transport and toxicity
Grantee:Leonardo Fernandes Fraceto
Support type: Research Projects - Thematic Grants
FAPESP's process: 18/21142-1 - Encapsulation of Bacillus thuringiensis (Bacillales: Bacillaceae) in polymeric microparticles and association with nanoencapsulated chemical agent: evaluation of biological activity and mechanisms of action
Grantee:Jhones Luiz de Oliveira
Support type: Scholarships in Brazil - Post-Doctorate
FAPESP's process: 20/05816-2 - Study of the capping of biogenic nanoparticles and their correlation with toxicity and activity in the control of phytopathogens
Grantee:Mariana Guilger Casagrande
Support type: Scholarships in Brazil - Post-Doctorate