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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Effectiveness of the pelvic floor muscle training on muscular dysfunction and pregnancy specific urinary incontinence in pregnant women with gestational diabetes mellitus: A systematic review protocol

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Barbosa, Angelica Mercia Pascon [1] ; Enriquez, Eusebio Mario Amador [2] ; Rodrigues, Meline Rossetto Kron [3] ; Prudencio, Caroline Baldini [2] ; Atallah, Alvaro Nagib [4] ; Reyes, David Rafael Abreu [2] ; Hallur, Raghavendra Lakshmana Shetty [2] ; Nunes, Sthefanie Kenickel [2] ; Pinheiro, Fabiane Affonso [2] ; Sartorao Filho, Carlos Isaias [2] ; Andrade, Gabriela Lopes Piemonte [5] ; Berghmans, Bary [6] ; Bie, Rob de [6] ; Lima, Silvana Andrea Molina [7] ; Rudge, Marilza Vieira Cunha [2] ; Grp, Diamater Study
Total Authors: 16
Affiliation:
[1] Sao Paulo State Univ UNESP, Sch Philosophy & Sci, Dept Physiotherapy & Occupat Therapy, Marilia, SP - Brazil
[2] Sao Paulo State Univ UNESP, Botucatu Med Sch FMB, Dept Gynecol & Obstet, Botucatu, SP - Brazil
[3] Guarulhos Univ UNG, Stricto Sensu Grad Program Nursing UNIVERITAS, Guarulhos, SP - Brazil
[4] Fed Univ Sao Paulo EPM UNIFESP, Paulista Sch Med, Discipline Evidence Based Med, Sao Paulo - Brazil
[5] Univ Oeste Paulista UNOESTE, Dept Physiotherapy, Presidente Prudente, SP - Brazil
[6] Maastricht Univ, Med Ctr, Pelv Care Ctr Maastricht, Maastricht - Netherlands
[7] Sao Paulo State Univ UNESP, Botucatu Med Sch FMB, Dept Nursing, Botucatu, SP - Brazil
Total Affiliations: 7
Document type: Review article
Source: PLoS One; v. 15, n. 12 DEC 7 2020.
Web of Science Citations: 0
Abstract

Background There is ample evidence that gestational diabetes mellitus has a direct influence on urinary incontinence and pelvic floor muscles. There are no standardized pelvic floor muscle exercise programs in the literature for the physiotherapy and differ in the type of exercise, intensity, type and duration of application, and the frequency and duration of treatment sessions. The aim of this systematic review will be to investigate that Pelvic Floor Muscle Training can prevent and/or decrease the pregnancy specific urinary incontinence in women with gestational diabetes mellitus or gestational hyperglycemia. Methods We will perform a systematic review according to the Cochrane methodology of Randomized Controlled Trials. An overall search strategy will be developed and adapted for Embase, MEDLINE, LILACS, and CENTRAL databases, with the date of consultation until June 2020. The MeSH terms used will be ``Pregnancy{''}, ``Hyperglycemia{''}, ``Diabetes Mellitus, Type 2{''}, ``Diabetes Mellitus, Type 1{''}, ``Pregnancy in Diabetics{''}, ``Diabetes, Gestational{''}, ``Urinary Incontinence{''}, ``Pelvic Floor Muscle Strength{''}. Primary outcomes: improvement or cure of pregnancy specific urinary incontinence (which can be assessed by questionnaires, and tools such as tampon test, voiding diary, urodynamic study). Secondary outcomes: improvement of pelvic floor muscle strength (pelvic floor functional assessment, perineometer, electromyography, functional ultrasonography), improved quality of life (questionnaires), presence or absence of postpartum Urinary Incontinence and adverse effects. Quality assessment by Cochrane instrument. Metanalysis if plausible, will be performed by the software Review Manager 5.3. Discussion The present study will be the first to analyze the effectiveness of pelvic floor exercises in pregnant women with Gestational Diabetes Mellitus or Hyperglycemia, who suffer from pregnancy specific urinary incontinence. Randomized Controlled Trials design will be chosen because they present the highest level of evidence. It is expected to obtain robust and conclusive evidence to support clinical practice, in addition to promoting studies on the theme and contributing to new studies. (AU)

FAPESP's process: 16/01743-5 - The new gestational triad: hyperglycemia, urinary incontinence (UI) and biomolecular profile as a long-term predictor for UI: a prospective cohort study: translational research with biodevice with stem cells for muscle regeneration in diabetic rats
Grantee:Marilza Vieira Cunha Rudge
Support Opportunities: Research Projects - Thematic Grants
FAPESP's process: 18/17534-1 - Training and improvement in the implementation of standards for systematic review of Collaboration Cochrane on exercise effectiveness on pelvic floor muscle dysfunction and pregnancy-specific urinary incontinence of hyperglycemic pregnant women
Grantee:Eusebio Mario Amador Enriquez
Support Opportunities: Scholarships in Brazil - Technical Training Program - Technical Training