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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Antioxidant potential of nature's ``something blue{''}: Something new in the marriage of biological activity and extraction methods applied to C-phycocyanin

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Fratelli, Camilly [1, 2, 3] ; Burck, Monize [1, 2] ; Assumpca Amarant, Marina Campos [4] ; Cavalcante Braga, Anna Rafaela [5, 1]
Total Authors: 4
[1] Univ Fed Sao Paulo UNIFESP, Dept Biosci, Silva Jardim St 136, BR-11015020 Santos, SP - Brazil
[2] Univ Fed Sao Paulo UNIFESP, Dept Physiol, Botucatu St 740, BR-04023062 Sao Paulo, SP - Brazil
[3] Univ Metropolitana Santos UNIMES, Gen Francisco Glicerio Ave 8, BR-11045002 Santos, SP - Brazil
[4] Univ Birmingham, Sch Chem Engn, Birmingham B15 2TT, W Midlands - England
[5] Univ Fed Sao Paulo UNIFESP, Dept Chem Engn, Campus Diadema, BR-09972270 Sao Paulo - Brazil
Total Affiliations: 5
Document type: Journal article
Source: TRENDS IN FOOD SCIENCE & TECHNOLOGY; v. 107, p. 309-323, JAN 2021.
Web of Science Citations: 0

Background: C-phycocyanin (C-PC), a blue-colored natural pigment, is Spirulina's most crucial photosynthetic protein, and it is associated with this cyanobacteria's bioactivity. Many recent studies aimed at optimizing C-PC extraction from Spirulina using different protocols; however, the correlation between the extraction method (both lab scale experimental methods and industrial methods) and the antioxidant activity of the extract has not been explored yet. Scope and approach: This review aimed to gather information regarding the most used C-PC extraction techniques from Spirulina in the last decade (2010-2020) and compare these biomolecules' antioxidant capacity with the extraction methodology applied. A density map was created by searching keywords related to C-PC extraction on Scopus, which guided the discussion on the C-PC extraction methods used and their impact on its bioactivity. Key findings and conclusions: The density map showed that the lowest density words represented factors that can influence, describe, or determine the success of C-PC extraction. In contrast, the most cited expressions were related to the methods. The compilation of literature on the influence of C-PC extraction on its antioxidant activity showed that ultrasound-assisted extraction (UAE) and solvent extraction using water or buffer were the most used methods to extract C-PC from Spirulina in the last decade. However, the UAE does not seem to protect C-PC's bioactivity. Additionally, most studies of the previous ten years used a single method to determine C-PC's antioxidant activity. We concluded that C-PC's antioxidant activity needs to be appraised by more than one method using assays of different mechanisms to evaluate the extraction influence in its bioactivity in a panoramic way. (AU)

FAPESP's process: 18/01550-8 - Nanoestructures containing anthocyanins extracted from juçara pulp (Euterpe edulis Mart.): Interaction with lactic acid bacteria and bioavailability
Grantee:Anna Rafaela Cavalcante Braga
Support Opportunities: Regular Research Grants
FAPESP's process: 20/06732-7 - A panoramic study for the use of Spirulina biomass: from the bioactive compound's extraction to their encapsulation and application
Grantee:Anna Rafaela Cavalcante Braga
Support Opportunities: Regular Research Grants
FAPESP's process: 18/13408-1 - Multi-user equipment approved in grant 2018/01550-8: electro-spray equipment to obtain bioactive compounds into nanostructures
Grantee:Anna Rafaela Cavalcante Braga
Support Opportunities: Multi-user Equipment Program