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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Tridimensional dose evaluation of the respiratory motion influence on breast radiotherapy treatments using conformal radiotherapy, forward IMRT, and inverse IMRT planning techniques

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Author(s):
Lizar, Jessica Caroline [1] ; Volpato, Karina Cristina [2] ; Brandao, Fernanda Calixto [2] ; Guimaraes, Flavio da Silva [2] ; Arruda, Gustavo Viani [3] ; Pavoni, Juliana Fernandes [1, 3]
Total Authors: 6
Affiliation:
[1] Univ Sao Paulo, Fac Philosophy Sci & Letters Ribeirao Preto, Dept Phys, Av Bandeirantes 3900, BR-14040901 Ribeirao Preto, SP - Brazil
[2] Sao Carlos Radiotherapy Ctr, Rua Maestro Joao Seppe S-N, BR-13561180 Sao Carlos - Brazil
[3] Univ Sao Paulo, Ribeirao Preto Med Sch Hosp & Clin, Radiotherapy Dept, Av Bandeirantes 3900, BR-14040900 Ribeirao Preto, SP - Brazil
Total Affiliations: 3
Document type: Journal article
Source: PHYSICA MEDICA-EUROPEAN JOURNAL OF MEDICAL PHYSICS; v. 81, p. 60-68, JAN 2021.
Web of Science Citations: 0
Abstract

Purpose: To evaluate the respiratory motion influence on the tridimensional (3D) dose delivery to breast-shaped phantoms using conformal radiotherapy (3D-RT), Field-in Field (FiF), and IMRT planning techniques. Methods: This study used breast-shaped phantoms filled with MAGIC-f gel dosimeter to simulate the breast, and an oscillation platform to simulate the respiratory motion. The platform allowed motion in the anterior-posterior direction with oscillation amplitudes of 0.34 cm, 0.88 cm, and 1.22 cm. CT images of the static phantom were used for the 3D-RT, FiF, and IMRT treatment planning. Five phantoms were prepared and irradiated for each planning technique evaluated. Phantom 1 was irradiated static, phantoms 2-4 were irradiated moving with the three different motion amplitudes, and phantom 5 was used as a reference. The 3D dose distributions were obtained by relaxometry of magnetic resonance imaging, and the respiratory motion influence in the doses distribution was accessed by gamma evaluations (3%/3mm/15% threshold) comparing the measurements of the phantoms irradiated under movement with the static ones. Results: The mean gamma approvals for three oscillatory amplitudes were 96.44%, 93.23%, and 91.65%; 98.42%, 95.66%, and 94.31%; and 94.49%, 93.51%, and 86.62% respectively for 3D-RT, FiF and IMRT treatments. A gamma results profile per slice along the phantom showed that for FiF and IMRT irradiations, most of the failures occurred in the central region of the phantom. Conclusions: By increasing the respiratory motion movement, the dose distribution variations for the three planning techniques were more pronounced, being the FiF technique variations the smallest one. (AU)

FAPESP's process: 14/03370-6 - Clinical applications and optimization of polymeric gel dosimetry technique
Grantee:Juliana Fernandes Pavoni
Support type: Regular Research Grants