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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Understanding the mixed alkali effect on the sinterability and in vitro performance of bioactive glasses

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Author(s):
Crovace, Murilo C. [1] ; Soares, Viviane O. [2] ; Rodrigues, Ana Candida M. [1] ; Peitl, Oscar [1] ; Raucci, Larissa M. S. C. [3] ; de Oliveira, Paulo T. [3] ; Zanotto, Edgar D. [1]
Total Authors: 7
Affiliation:
[1] Univ Fed Sao Carlos, Dept Mat Engn, Vitreous Mat Lab LaMaV, Sao Carlos, SP - Brazil
[2] Univ Estadual Maringa, Dept Sci, Goioere, PR - Brazil
[3] Univ Sao Paulo, Sch Dent Ribeirao Preto, Cell Culture Lab, Ribeirao Preto, SP - Brazil
Total Affiliations: 3
Document type: Journal article
Source: Journal of the European Ceramic Society; v. 41, n. 7, p. 4391-4405, JUL 2021.
Web of Science Citations: 2
Abstract

Bioglass 45S5 is widely known for its ability to regenerate bone. However, this glass cannot be fully densified by viscous flow due to its very high tendency for crystallization. In this work, we evaluate the sintering and bioactivity of Bioglass 45S5-based compositions in which Na2O is incrementally replaced by K2O. Our sintering tests demonstrated that the densification of Bioglass 45S5 powders can be significantly enhanced due to a decreased crystallization tendency. The composition in which half of the original Na2O content was substituted by K2O exhibits the highest densification rate, evidencing the mixed alkali effect (MAE) in the viscous-flowdriven sintering process. The replacement of Na2O by K2O significantly improved both the densification rate and the in vitro performance. These results are very relevant for this particular glass and also for the design of new bioactive glasses with improved sinterability. (AU)

FAPESP's process: 08/11539-0 - Synthesis of scaffolds by sintering of glassy Biosilicate® with concurrent crystallization
Grantee:Murilo Camuri Crovace
Support Opportunities: Scholarships in Brazil - Doctorate
FAPESP's process: 13/07793-6 - CEPIV - Center for Teaching, Research and Innovation in Glass
Grantee:Edgar Dutra Zanotto
Support Opportunities: Research Grants - Research, Innovation and Dissemination Centers - RIDC
FAPESP's process: 13/07059-0 - Bioactive glass-ceramic scaffolds applicable to orthopedics and dentistry obtained by three-dimensional technologies
Grantee:Murilo Camuri Crovace
Support Opportunities: Scholarships in Brazil - Post-Doctoral