A nano perspective behind the COVID-19 pandemic

Author(s)

Silveira, Camila Pedroso ^[1] ; Schneid, Andressa da Cruz ^[1] ; Ribeiro, Iris Renata Sousa ^{[1, 2]} ; Galdino, Flavia Elisa ^{[1, 2]} ; Cardoso, Mateus Borba ^{[1, 2]}

Affiliation

^[1] Brazilian Ctr Res Energy & Mat CNPEM, Brazilian Synchrotron Light Lab LNLS, BR-13083970 Campinas - Brazil

^[2] Univ Campinas UNICAMP, Inst Chem IQ, POB 6154, BR-13083970 Campinas, SP - Brazil

• Document type: Review article
• Source: NANOSCALE HORIZONS; v. 6, n. 11 AUG 2021.
• Web of Science Citations: 0

Abstract

The global pandemic scenario has definitely pushed the scientific community to develop COVID-19 vaccines at unprecedented speed. Nevertheless, a worldwide vaccination campaign is still far from being achieved, making the usual precautionary measures as necessary as at the beginning of the outbreak. Many aspects of the SARS-CoV-2 infectious potential and disease severity do not solely rely on interactions at the molecular level but also on physical-chemical parameters that often involve nanoscale effects. Here the SARS-CoV-2 journey to infect a susceptible host is reviewed, focusing on the nanoscale aspects that play a role in the viral infectivity and disease progression. These nanoscale-driven interactions are essential to establish mitigation-related strategies. (AU)

• FAPESP's process: 19/14007-3 - Double-functionalised silica nanoparticles for anti-bacterial effect
• Grantee: Camila Pedroso Silveira Bueno
• Support Opportunities: Scholarships in Brazil - Post-Doctoral
• FAPESP's process: 15/25406-5 - Organizing matter: colloids formed by association of surfactants, polymers and nanoparticles
• Grantee: Watson Loh
• Support Opportunities: Research Projects - Thematic Grants
• FAPESP's process: 18/00763-8 - Synthesis of a Biodegradable Periodic Mesoporous Organosílica: A H. pylori Specific Drug Carrier
• Grantee: Andressa da Cruz Schneid
• Support Opportunities: Scholarships in Brazil - Post-Doctoral
• FAPESP's process: 17/21318-0 - Targeting of functionalized nanoparticles in microfluidics systems containing multiple organoids
• Grantee: Iris Renata Sousa Ribeiro
• Support Opportunities: Scholarships in Brazil - Doctorate
• FAPESP's process: 18/09555-9 - Influence of protein corona on interaction and internalization of silica nanoparticles in human cells: from two-dimensional to tri-dimensional images
• Grantee: Flávia Elisa Galdino
• Support Opportunities: Scholarships in Brazil - Doctorate