| Full text | |
| Author(s): |
Otto, Paulo A.
[1]
Total Authors: 1
|
| Affiliation: | [1] Univ Sao Paulo, Inst Biociencias, Dept Genet, Lab Genet Humana, Rua Matao 277, Cidade Univ, BR-05508090 Sao Paulo, SP - Brazil
Total Affiliations: 1
|
| Document type: | Journal article |
| Source: | GENETICS AND MOLECULAR BIOLOGY; v. 44, n. 3 2021. |
| Web of Science Citations: | 0 |
| Abstract | |
Abstract Besides reviewing the unusual case of sex-ratio in the lemming and presenting alternative analyses of general models in which the shift in the usual sex-ratio 1:1 is determined by autosomal or sex-linked mutant alleles, three novel models are presented, in which the shift on the progeny sex-ratio depends on the number of copies of a mutant allele present in the parental pair. The analysis of these models with additive effects shows that: 1) autosomal mutations that alter the usual sex-ratio are eliminated from the population; 2) mutations occurring on the X chromosome lead to an evolutionary stable 1:1 sex-ratio only if the mutation favors the production of males; when the mutant allele favors the production of females, however, females will prevail in the population, with a frequency dependent impact on δ (the deviation from the usual 0.5 proportion) ; for most of the range of possible values of δ the stable but extraordinary sex-ratio will vary from 1 male : 1 female to 1 male : 3 females or 1 male : 2 females approximately depending whether the mutant allele is randomly inactivated or not. (AU) | |
| FAPESP's process: | 11/10877-1 - Theoretical population genetics: models on forensic population genetics, sex-ratio, and larval development delay |
| Grantee: | Paulo Alberto Otto |
| Support Opportunities: | Scholarships abroad - Research |