Advanced search
Start date
(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Production of oral films based on pre-gelatinized starch, CMC and HPMC for delivery of bioactive compounds extract from acerola industrial waste

Full text
Tedesco, Marcela Perozzi [1] ; dos Santos Garcia, Vitor Augusto [1] ; Borges, Josiane Goncalves [1] ; Osiro, Denise [2] ; Vanin, Fernanda Maria [1] ; Pedroso Yoshida, Cristiana Maria [3] ; de Carvalho, Rosemary Aparecida [1]
Total Authors: 7
[1] Univ Sao Paulo, Fac Anim Sci & Food Engn, Av Duque Caxias Norte 225, BR-13635900 Pirassununga, SP - Brazil
[2] Univ Ctr Guaxupe Educ Fdn, Av Dona Floriana 463, BR-37800000 Guaxupe, MG - Brazil
[3] Univ Fed Sao Paulo, Inst Environm Chem & Pharmaceut Sci, Rua Sao Nicolau 210, BR-09913030 Diadema, SP - Brazil
Total Affiliations: 3
Document type: Journal article
Web of Science Citations: 0

The residue from the processing of acerola, due to the concentration of active compounds, and antioxidant potential has aroused interest in its application. In this context, this study aimed to produce and characterization oral films based on carboxymethyl cellulose (CMC), hydroxypropyl methylcellulose (HPMC) and pre-gelatinized starch with the incorporation of ethanolic extract of dehydrated acerola industrial waste (EEDAIW) using tape -casting technique. The rheological properties of filmogenic solutions of CMC, HPMC, and starch were assessed. Oral films were characterized in relation to color parameters, mechanical properties, surface pH, contact angle, Fourier transform infrared (FTIR) spectroscopy, atomic force microscopy, and stability in relation to total phenolic compounds. It was found that apparent viscosity decreased with the deformation rate and the expected behavior of pseudoplastic fluids, regardless of the polymer used. In general, the addition of EEDAIW in the films led to a reduction in the tensile strength of the films and an increase in the contact angle values; however, the surface pH of the films remained close to the oral pH (6.8). From the FTIR, it was found that even after the addition of EEDAIW, all films showed predominant absorption bands, characteristic of the polymer used. It was found that after 84 days, CMC-based films had a higher concentration of total phenolic compounds when compared to HPMC and starch oral films. (AU)

FAPESP's process: 16/16250-4 - Extraction and vehiculation of active compounds from industrial waste Acerola and Camu Camuin natural polymer based films produced by tape casting
Grantee:Rosemary Aparecida de Carvalho
Support Opportunities: Regular Research Grants