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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Cardiorespiratory and skeletal muscle damage due to COVID-19: making the urgent case for rehabilitation

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Silva, Rebeca Nunes [1] ; Goulart, Cassia Da Luz [1] ; Oliveira, Murilo Rezende [1] ; Tacao, Guilherme Yassuyuki [2] ; Back, Guilherme Dionir [1] ; Severin, Richard [3, 4] ; Faghy, Mark A. [3, 5] ; Arena, Ross [3, 6] ; Borghi-Silva, Audrey [1, 3]
Total Authors: 9
[1] Fed Univ Sao Carlos Ufscar, Dept Physiotherapy, Cardiopulm Physiotherapy Lab, Rod Washington Luis, KM 235, BR-13565905 Sao Carlos, SP - Brazil
[2] Sao Paulo State Univ UNESP, Fac Sci & Technol, Postgrad Program Physiotherapy, Dept Physiotherapy, Presidente Prudente, SP - Brazil
[3] Hlth Living Pandem Event Protect HL PIVOT Network, Dept Phys Therapy, Chicago, IL - USA
[4] Baylor Univ, Robbins Coll Appl Hlth Sci, Dept Phys Therapy, Waco, TX 76798 - USA
[5] Univ Derby, Human Sci Res Ctr, Dept Sch Human Sci, Derby - England
[6] Univ Illinois, Coll Appl Hlth Sci, Dept Phys Therapy Dept, Chicago, IL - USA
Total Affiliations: 6
Document type: Review article
Source: EXPERT REVIEW OF RESPIRATORY MEDICINE; v. 15, n. 9, p. 1107-1120, SEP 2 2021.
Web of Science Citations: 0

Introduction: It has become increasingly evident that COVID-19 contributes to multiorgan pathophysiology. The systemic inflammatory response increases both pro-inflammatory cytokine and chemokine levels, leading to immune dysregulation and increasing the likelihood of incurring cardiac and pulmonary injuries. Areas covered: Longer periods of hospitalization (similar to 20 days) increase susceptibility to ICU-acquired muscle weakness and deconditioning, which decreases muscle function and functional capacity. These conditions affect the quality of life in the post-COVID-19 period and require multi-disciplinary approaches to rehabilitate the cardiopulmonary and musculoskeletal systems of these patients. In this context, this narrative review, which included articles published in the Embase, PEDro and PubMed databases up to December 2020, is focused on discussing the essential role of exercise and rehabilitation health professionals in the COVID-19 recovery process, from hospitalization to hospital discharge, addressing strategies for professionals to mitigate the cardiac and pulmonary impairments associated with hospitalization to home or ambulatory rehabilitation, purposing ways to conduct rehabilitation programs to restore their functional status and quality of life after the infection. Expert opinion: In the current environment, these findings further point to the vital role of rehabilitation health professionals in the coming years and the urgent need to develop strategies to assist COVID-19 survivors. (AU)

FAPESP's process: 15/26501-1 - Study of limiting factors to physical exercise and adjunct effects to rehabilitation on cardiorespiratory disease: a multicentre approach
Grantee:Audrey Borghi e Silva
Support Opportunities: Research Projects - Thematic Grants