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(Reference retrieved automatically from SciELO through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Progress in the photodynamic therapy treatment of Leishmaniasis

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Author(s):
D.G. Vital-Fujii [1] ; M.S. Baptista [2]
Total Authors: 2
Affiliation:
[1] Instituto de Química, Universidade de São Paulo. Departamento de Bioquímica - Brasil
[2] Instituto de Química, Universidade de São Paulo. Departamento de Bioquímica - Brasil
Total Affiliations: 2
Document type: Journal article
Source: Brazilian Journal of Medical and Biological Research; v. 54, n. 12 2021-10-29.
Abstract

Leishmaniasis is a serious and endemic infectious disease that has been reported in more than 90 countries and territories. The classical treatment presents a series of problems ranging from difficulty in administration, development of resistance, and a series of side effects. Photodynamic therapy (PDT) has already shown great potential for use as a treatment for leishmaniasis that is effective and non-invasive, with very minor side effects. PDT can also be inexpensive and easy to administer. In this review, we will report the most recent developments in the field, starting with the chemical diversity of photosensitizers, highlighting important mechanistic aspects, and noting information that may assist in designing and developing new and promising photosensitizer molecules. (AU)

FAPESP's process: 18/24190-7 - EFFICIENCY OF RUTHENIUM COMPLEXES AND PORPHYRIN DERIVATIVES IN PHOTODYNAMIC THERAPY IN Leishmania amazonensis
Grantee:Drielli Gomes Vital Fujii
Support type: Scholarships in Brazil - Post-Doctorate
FAPESP's process: 13/07937-8 - Redoxome - Redox Processes in Biomedicine
Grantee:Ohara Augusto
Support type: Research Grants - Research, Innovation and Dissemination Centers - RIDC