| Full text | |
| Author(s): |
Costa, Mayra F.
[1]
;
Luiz, Mayara M.
[1]
;
Souza, Leonardo C. de
[1]
;
Tempone, Andre G.
[2]
;
Lago, Joao Henrique G.
[3]
;
Nascimento, Isabele R.
[1]
Total Authors: 6
|
| Affiliation: | [1] Univ Estadual Paulista UNESP, Inst Quim, BR-14800060 Araraquara, SP - Brazil
[2] Adolfo Lutz Inst, Ctr Parasitol & Micol, BR-01246902 Sao Paulo, SP - Brazil
[3] Univ Fed ABC, Ctr Ciencias Nat & Humanas, BR-09210180 Santo Andre, SP - Brazil
Total Affiliations: 3
|
| Document type: | Journal article |
| Source: | PHYTOCHEMISTRY LETTERS; v. 46, p. 1-5, DEC 2021. |
| Web of Science Citations: | 0 |
| Abstract | |
Nineteen compounds were isolated from the aerial parts and roots of Pontederia crassipes Mart. {[}equivalent to Eichhornia crassipes (Mart.) Solms] (Pontederiaceae), including the new 4-hydroxy-5-phenyl-1,8-naphthalic anhydride (1) and 4-hydroxy-5-(4-hydroxyphenyl)-1,8-naphthalic anhydride (2). In addition, chemically related phenylnaphthalic acid derivatives 1a and 2a were obtained. The structures of the compounds were established by 1D and 2D NMR and ESI-HRMS analysis. 8-Phenyl-phenalenones 3 and 4 were evaluated for antiprotozoal activity against trypomastigote forms of Trypanosoma cruzi and displayed moderate activity. (AU) | |
| FAPESP's process: | 21/02789-7 - Search for bioactive metabolites with antiparasitic action in plant species from Atlantic Forest and Cerrado regions - a chemical, phenotypical, and metabolomic approach |
| Grantee: | João Henrique Ghilardi Lago |
| Support Opportunities: | BIOTA-FAPESP Program - Regular Research Grants |