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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

The effect of photodynamic therapy on postoperative pain in teeth with primary endodontic infection

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Alves-Silva, Esdras Gabriel [1] ; Arruda-Vasconcelos, Rodrigo [1] ; Louzada, Lidiane Mendes [1] ; de-Jesus-Soares, Adriana [1] ; Ferraz, Caio Cezar Randi [1] ; Almeida, Jose Flavio Affonso [1] ; Marciano, Marina Angelica [1] ; Steiner-Oliveira, Carolina [2] ; Bello-Silva, Marina Stella [3] ; Shemesh, Hagay [4, 5] ; Gomes, Brenda Paula Figueiredo de Almeida [1]
Total Authors: 11
[1] Univ Estadual Campinas, Piracicaba Dent Sch, Div Endodont, Dept Restorat Dent, UNICAMP, POB 52, BR-13414903 Piracicaba, SP - Brazil
[2] Univ Estadual Campinas, Piracicaba Dent Sch, Dept Hlth Sci & Pediat Dent, UNICAMP, Piracicaba, SP - Brazil
[3] Univ Sao Paulo, Dept Restorat Dent, Sch Dent, Special Lab Lasers Dent LELO, Sao Paulo, SP - Brazil
[4] Vrije Univ Amsterdam, Amsterdam - Netherlands
[5] Univ Amsterdam, Acad Ctr Dent Amsterdam ACTA, Dept Endodontol, Amsterdam - Netherlands
Total Affiliations: 5
Document type: Journal article
Source: Photodiagnosis and Photodynamic Therapy; v. 37, MAR 2022.
Web of Science Citations: 0

Introduction: : The objective of this study was to investigate the action of photodynamic therapy on pain control after endodontic treatment in asymptomatic teeth with a primary infection, within a single visit. Methods: : Sixty (60) single-rooted teeth with pulp necrosis and periapical lesions were selected and randomly divided into two (2) groups (n = 30), according to the protocol; a control group (CG) and a group using photodynamic therapy (aPDT). The canals were instrumented with Reciproc files \# 25 up to 40 along the entire length of the canal, using 2% chlorhexidine gel as the auxiliary chemical substance, followed by irrigation with sterile saline. aPDT consited of 0.005% methylene blue as photosensitizer, using AsGaAl diode laser, 660 nm wavelength, 100 mW of power and 9 J of energy, using optical fibers with 365 pm in diameter. The canals were filled with Endomethasone N cement. Results: : Pain intensity was assessed at 8, 12, 24, 48, 72 h and 1 week after endodontic treatment using a visual analogue scale. The level of pain was classified as none (0), mild (1-3), moderate (4-7) or severe (8-10). The data were at a significance level of 5%. There was a statistically significant difference (p<0.05) in the periods of 8, 12, 24, 48 and 72 h between the control group and the aPDT group. After 1 week, there was no statistically significant difference. Conclusions: : It is concluded that photodynamic therapy had a significant effect on decreasing post-endodontic treatment pain in teeth with necrotic pulp and asymptomatic periapical lesions. (AU)

FAPESP's process: 19/19300-0 - Investigation of the clinical, microbiological and immunological aspects of teeth with diagnosis of primary periodontal lesions with secondary endodontic involvement
Grantee:Lidiane Mendes Louzada
Support type: Scholarships in Brazil - Doctorate
FAPESP's process: 17/25242-8 - Clinical, microbiological and immunological monitoring of patients undertaken to endodontic therapy with diagnosis of irreversible Pulpitis
Grantee:Rodrigo Arruda Vasconcelos
Support type: Scholarships in Brazil - Doctorate
FAPESP's process: 19/10755-5 - Clinical investigation of epigenetic modulations in dental pulp tissues with diagnosis of irreversible pulpitis
Grantee:Rodrigo Arruda Vasconcelos
Support type: Scholarships abroad - Research Internship - Doctorate
FAPESP's process: 15/23479-5 - Microbiomes and immunobiological aspects in endodontic infections
Grantee:Brenda Paula Figueiredo de Almeida Gomes
Support type: Research Projects - Thematic Grants
FAPESP's process: 19/09115-1 - Effect of chemomechanical preparation associated with photodynamic therapy in the reduction of microbial, LPS, LTA, substance p and pro-inflammatory cytokines in primary endodontic infection
Grantee:Esdras Gabriel Alves e Silva
Support type: Scholarships in Brazil - Master