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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

ynapenia, abdominal obesity or both: which accelerates the gait speed decline most

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Maximo, Roberta de Oliveira [1] ; de Oliveira, Dayane Capra [1] ; Camila Ramirez, Paula [1, 2] ; Luiz, Mariane Marques [1] ; de Souza, Aline Fernanda [1] ; Bicigo Delinocente, Maicon Luis [3] ; Steptoe, Andrew [4] ; de Oliveira, Cesar [4] ; Alexandre, Tiago da Silva [4, 5, 1, 3]
Total Authors: 9
[1] Univ Fed Sao Carlos, Phys Therapy Postgrad Program, Sao Carlos - Brazil
[2] Univ Ind Santander, Escuela Fisioterapia, Santander - Colombia
[3] Univ Fed Sao Carlos, Gerontol Postgrad Program, Sao Carlos - Brazil
[4] UCL, Dept Epidemiol & Publ Hlth, London - England
[5] Univ Fed Sao Carlos, Dept Gerontol, Sao Carlos - Brazil
Total Affiliations: 5
Document type: Journal article
Source: AGE AND AGEING; v. 50, n. 5, p. 1616-1625, SEP 2021.
Web of Science Citations: 0

Objective: to investigate whether the combination of dynapenia and abdominal obesity is worse than these two conditions separately regarding gait speed decline over time. Methods: a longitudinal study was conducted involving 2,294 individuals aged 60 years or older free of mobility limitation at baseline (gait speed >0.8 m/s) who participated in the English Longitudinal Study of Ageing. Dynapenia was determined as a grip strength <26 kg for men and <16 kg for women. Abdominal obesity was determined as a waist circumference >102 cm for men and >88 cm for women. The participants were divided into four groups: non-dynapenic/non-abdominal obese (ND/NAO); only abdominal obese (AO); only dynapenic (D) and dynapenic/abdominal obese (D/AO). Generalised linear mixed models were used to analyse gait speed decline (m/s) as a function of dynapenia and abdominal obesity status over an 8-year follow-up period. Results: over time, only the D/AO individuals had a greater gait speed decline (-0.013 m/s per year, 95% CI: -0.024 to -0.002; P < 0.05) compared to ND/NAO individuals. Neither dynapenia nor abdominal obesity only was associated with gait speed decline. Conclusion: dynapenic abdominal obesity is associated with accelerated gait speed decline and is, therefore, an important modifiable condition that should be addressed in clinical practice through aerobic and strength training for the prevention of physical disability in older adults. (AU)

FAPESP's process: 18/13917-3 - Musculoskeletal aging: metabolic and functional repercussions and mortality risk in people aged 50 and older
Grantee:Tiago da Silva Alexandre
Support Opportunities: Research Grants - Young Investigators Grants
FAPESP's process: 17/26377-4 - Sex differences in the effect of Dynapenic Abdominal Obesity on the trajectories of mobility decline and lower extremity function in people over 50 years
Grantee:Roberta de Oliveira Máximo
Support Opportunities: Scholarships in Brazil - Doctorate