| Full text | |
| Author(s): Show less - |
G.D. Back
[1]
;
M.R. Oliveira
[2]
;
P.F. Camargo
[3]
;
C.L. Goulart
[4]
;
C.R. Oliveira
[5]
;
K.W. Wende
[6]
;
J.C. Bonjorno Junior
[7]
;
R.F. Arbex
[8]
;
F.R. Caruso
[9]
;
R. Arena
;
A. Borghi-Silva
Total Authors: 11
|
| Affiliation: Show less - | [1] Universidade Federal de São Carlos. Laboratório de Fisioterapia Cardiopulmonar, Departamento de Fisioterapia - Brasil
[2] Universidade Federal de São Carlos. Laboratório de Fisioterapia Cardiopulmonar, Departamento de Fisioterapia - Brasil
[3] Universidade Federal de São Carlos. Laboratório de Fisioterapia Cardiopulmonar, Departamento de Fisioterapia - Brasil
[4] Universidade Federal de São Carlos. Laboratório de Fisioterapia Cardiopulmonar, Departamento de Fisioterapia - Brasil
[5] Universidade Federal de São Carlos. Laboratório de Fisioterapia Cardiopulmonar, Departamento de Fisioterapia - Brasil
[6] Universidade Federal de São Carlos. Laboratório de Fisioterapia Cardiopulmonar, Departamento de Fisioterapia - Brasil
[7] Universidade Federal de São Carlos. Laboratório de Fisioterapia Cardiopulmonar, Departamento de Fisioterapia - Brasil
[8] Universidade Federal de São Carlos. Laboratório de Fisioterapia Cardiopulmonar, Departamento de Fisioterapia - Brasil
[9] Universidade Federal de São Carlos. Laboratório de Fisioterapia Cardiopulmonar, Departamento de Fisioterapia - Brasil
Total Affiliations: 11
|
| Document type: | Journal article |
| Source: | Brazilian Journal of Medical and Biological Research; v. 55, 2022-07-13. |
| Abstract | |
The goal of the present study was to compare pulmonary function test (PFT) and cardiopulmonary exercise test (CPET) performance in COVID-19 survivors with a control group (CG). This was a cross-sectional study. Patients diagnosed with COVID-19, without severe signs and symptoms, were evaluated one month after the infection. Healthy volunteers matched for sex and age constituted the control group. All volunteers underwent the following assessments: i) clinical evaluation, ii) PTF; and iii) CPET on a cycle ergometer. Metabolic variables were measured by the CareFusion Oxycon Mobile device. In addition, heart rate responses, peak systolic and diastolic blood pressure, and perceived exertion were recorded. Twenty-nine patients with COVID-19 and 18 healthy control subjects were evaluated. Surviving patients of COVID-19 had a mean age of 40 years and had higher body mass index and persistent symptoms compared to the CG (P<0.05), but patients with COVID-19 had more comorbidities, number of medications, and greater impairment of lung function (P<0.05). Regarding CPET, patients surviving COVID-19 had reduced peak workload, oxygen uptake (V̇O2), carbon dioxide output (V̇CO2), circulatory power (CP), and end-tidal pressure for carbon dioxide (PETCO2) (P<0.05). Additionally, survivors had depressed chronotropic and ventilatory responses, low peak oxygen saturation, and greater muscle fatigue (P<0.05) compared to CG. Despite not showing signs and symptoms of severe disease during infection, adult survivors had losses of lung function and cardiorespiratory capacity one month after recovery from COVID-19. In addition, cardiovascular, ventilatory, and lower limb fatigue responses were the main exercise limitations. (AU) | |
| FAPESP's process: | 20/15726-0 - Evaluation of pulmonary and endothelial function, autonomic cardiac control and its relation to the exercise capacity in surviving patients of COVID-19: a segment study |
| Grantee: | Guilherme Dionir Back |
| Support Opportunities: | Scholarships in Brazil - Doctorate (Direct) |
| FAPESP's process: | 15/26501-1 - Study of limiting factors to physical exercise and adjunct effects to rehabilitation on cardiorespiratory disease: a multicentre approach |
| Grantee: | Audrey Borghi e Silva |
| Support Opportunities: | Research Projects - Thematic Grants |