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(Reference retrieved automatically from SciELO through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Osseointegration of implants with superhydrophilic surfaces in rats with high serum levels of nicotine

Full text
Author(s):
Felipe Eduardo Pinotti [1] ; Maurício Andrés Tinajero Aroni [2] ; Guilherme José Pimentel Lopes de Oliveira [3] ; Bruno Luís Graciliano Silva [4] ; Elcio Marcantonio Junior [5] ; Rosemary Adriana Chiérici Marcantonio [6]
Total Authors: 6
Affiliation:
[1] São Paulo State University. School of Dentistry - Brasil
[2] San Francisco de Quito University - Equador
[3] Universidade Federal de Uberlândia. School of Dentistry - Brasil
[4] São Paulo State University. School of Dentistry - Brasil
[5] São Paulo State University. School of Dentistry - Brasil
[6] São Paulo State University. School of Dentistry - Brasil
Total Affiliations: 6
Document type: Journal article
Source: Brazilian Dental Journal; v. 34, n. 2, p. 105-112, 2023-05-15.
Abstract

Abstract This study aimed to evaluate the effect of nicotine administration on the osseointegration of a superhydrophilic implants surface on rat tibiae. Thirty-two rats were used and divided into 2 groups according to the administration or not of nicotine: HH - Installation of implants with superhydrophilic surfaces in healthy animals; and HN - Installation of implants with superhydrophilic surfaces in animals subjected to nicotine administration. The animals were euthanized 15 and 45 days after implant placement (n = 8). Osseointegration was assessed by means of biomechanical analyses (removal torque), microcomputed tomography (volume of bone around the implants- %BV/TV), and histomorphometry (bone-implant contact -%BIC and the bone area between implant threads -%BBT). The animals subject to the nicotine administration presented lower removal torque than the control animals at the 45-day period (21.88 ± 2.80 Ncm vs. 17.88 ± 2.10 Ncm). The implants placed in the control rats presented higher %BIC (54.26 ± 6.59% vs. 39.25 ± 4.46%) and %BBT (50.57 ± 5.28% vs. 32.25 ± 5.24%) than the implants placed in nicotine animals at 15-day period. The nicotine administration reduces the osseointegration at 15 days, however, the superhydrophilic surface equalized the osseointegration in nicotine-exposed animals compared with healthy animals after 45 days of implant placement. (AU)

FAPESP's process: 18/01610-0 - Evaluation of osseointegration of ACQUA implants in rats with systemic involvement
Grantee:Felipe Eduardo Pinotti
Support Opportunities: Scholarships in Brazil - Doctorate