Simultaneous determination of nine high-intensity sweeteners in liquid and powder tabletop sweeteners

Author(s)

Nicoluci, Icaro Gouvea ; da Silva, Beatriz Scardua ; de Campos Braga, Patricia Aparecida ; Bragotto, Adriana Pavesi Arisseto

• Document type: Journal article
• Source: Food Additives and Contaminants Part A-Chemistry Analysis Control Exposure; v. 40, n. 10, p. 9-pg., 2023-09-10.

Abstract

Government regulatory actions and public policies have been recently implemented in Brazil due to the excessive consumption of sugar. Therefore, it becomes relevant to determine the levels of high-intensity sweeteners in tabletop sweeteners consumed by the Brazilian population. Thus, an analytical method was developed and validated for the simultaneous determination of nine sweeteners (acesulfame potassium, aspartame, advantame, sodium cyclamate, neotame, saccharin, sucralose, stevioside, and rebaudioside A) by using ultra-high performance liquid chromatography coupled to mass spectrometry in tandem. The sample preparation encompassed only dilution steps. The method was validated taking into account the parameters of linearity, precision, accuracy, and matrix effects. The analytes were determined in two different batches of 21 commercial liquid and powder tabletop sweeteners available on the local market, totaling 42 samples. A minimum of one and a maximum of four sweeteners were found in the analyzed products and sweeteners that were not described on the label were not detected. It is expected that the established method can be used in monitoring programs and that the presented results can contribute to exposure assessments performed nationally. (AU)

• FAPESP's process: 21/02387-6 - Exposure of diabetic children to high intensity sweeteners through the diet: an integrated approach on health risks and food regulation
• Grantee: Adriana Pavesi Arisseto Bragotto
• Support Opportunities: Regular Research Grants