| Full text | |
| Author(s): |
Sedenho, Graziela C.
;
Colombo, Rafael N. P.
;
Crespilho, Frank N.
Total Authors: 3
|
| Document type: | Journal article |
| Source: | CHEMCATCHEM; v. N/A, p. 18-pg., 2023-07-06. |
| Abstract | |
Enzymes, especially some metalloenzymes, are exceptional catalysts for redox reactions with technological applications in several fields, including energy conversion systems and producing fuels and value-added chemicals. Because of that, they have inspired the development of synthetic catalysts to obtain high-performance materials. However, several fundamental aspects should be better understood to achieve this goal, such as enzyme catalysis and the role of the three-dimensional catalytic site. Therefore, this review addresses key structural and activity aspects of some remarkable metalloenzymes and discusses three-dimensional catalysis as an approach to enzyme catalysis. Also, the case of the multicopper oxidase enzymes is shown as an example of how the three-dimensional coordination environment of the copper ions in the active site can impact catalysis. (AU) | |
| FAPESP's process: | 21/05665-7 - Development of Van der Waals surfaces for application in biodevices |
| Grantee: | Rafael Neri Prystaj Colombo |
| Support Opportunities: | Scholarships in Brazil - Post-Doctoral |
| FAPESP's process: | 22/09164-5 - Understanding the charge transfer mechanisms in biological and biomimetic systems using in-situ and operando techniques: from fundamental science to energy application |
| Grantee: | Frank Nelson Crespilho |
| Support Opportunities: | Regular Research Grants |
| FAPESP's process: | 18/22214-6 - Towards a convergence of technologies: from sensing and biosensing to information visualization and machine learning for data analysis in clinical diagnosis |
| Grantee: | Osvaldo Novais de Oliveira Junior |
| Support Opportunities: | Research Projects - Thematic Grants |
| FAPESP's process: | 20/04796-8 - In situ and operando studies of metaloenzymes for energy conversion and fuel bioelectrosynthesis |
| Grantee: | Graziela Cristina Sedenho |
| Support Opportunities: | Scholarships in Brazil - Post-Doctoral |