| Full text | |
| Author(s): |
Souza Vera, Luana Janaina
[1]
;
Basano, Sergio de Almeida
[1, 2]
;
Almeida Aranha Camargo, Juliana de Souza
[1]
;
de Franca, Andonai Krauze
[3]
;
Mattos Ferreira, Ricardo de Godoi
[4]
;
Casseb, Almeida Andrade
[3]
;
Medeiros, Jansen Fernandes
[5, 6]
;
Fontes, Gilberto
[7]
;
Aranha Camargo, Luis Marcelo
[1, 8]
Total Authors: 9
|
| Affiliation: | [1] Fac Sao Lucas, Porto Velho, RO - Brazil
[2] Ctr Med Trop Rondonia, Setor Isolamento, Porto Velho, RO - Brazil
[3] Inst Pesquisa Patologias Tropicais, Genet Lab, Porto Velho, RO - Brazil
[4] Fundacao Oswaldo Cruz Noroeste, Lab Estudos Bioinformat & Bioestat, Porto Velho, RO - Brazil
[5] Inst Nacl de Pesquisas da Amazonia, Manaus, Amazonas - Brazil
[6] Univ Estadual Amazonas, Escola Super Ciencias Saude, Manaus, Amazonas - Brazil
[7] Univ Fed Sao Joao Rei, Ctr Ciencias Saude, Divinopolis, MG - Brazil
[8] Inst Ciencias Biomed 5, Dept Parasitol, Monte Negro, RO - Brazil
Total Affiliations: 8
|
| Document type: | Journal article |
| Source: | Revista da Sociedade Brasileira de Medicina Tropical; v. 44, n. 3, p. 380-382, MAY-JUN 2011. |
| Web of Science Citations: | 12 |
| Abstract | |
INTRODUCTION: Mansonelliasis is caused by Mansonella ozzardi. It is widespread in the Amazon region, with a high prevalence. The common exam of thick blood smears stained with Giemsa shows low efficacy levels and has been an obstacle to diagnosing individuals with low blood parasitemia. METHODS: In order to increase diagnosis efficacy, the PCR technique was improved. RESULTS AND CONCLUSIONS: PCR demonstrated the best performance, with sensitivity and negative predictive values (NPV) of 100%, followed by blood filtration through membrane filters, which showed a sensitivity of 88.9% and a NPV of 84.6%, when compared to thick blood smears. (AU) | |
| FAPESP's process: | 08/10817-6 - Clinical trial with ivermectine for the treatment of Mansonella ozzardi infections |
| Grantee: | Luís Marcelo Aranha Camargo |
| Support Opportunities: | Regular Research Grants |