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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Histological Outcomes on the Development of New Space-making Devices for Maxillary Sinus Floor Augmentation

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Cricchio, Giovanni [1] ; Palma, Vinicious Canavarros [2] ; Faria, Paolo E. P. [3] ; de Olivera, Jose Americo [4] ; Lundgren, Stefan [1] ; Sennerby, Lars [5] ; Salata, Luiz A. [6]
Total Authors: 7
[1] Umea Univ, Dept Oral & Maxillofacial Surg, SE-90187 Umea - Sweden
[2] Univ Cuiaba, Fac Dent Cuiaba, Dept Oral & Maxillofacial Surg & Integrated Clin, Cuiaba, Mato Grosso - Brazil
[3] Univ State Sao Paulo, Fac Dent Aracatuba, Dept Oral & Maxillofacial Surg, Sao Paulo - Brazil
[4] Univ State Sao Paulo, Fac Dent Aracatuba, Dept Basic Sci, Sao Paulo - Brazil
[5] Gothenburg Univ, Dept Biomat, Gothenburg - Sweden
[6] Univ Sao Paulo, Dept Oral & Maxillofacial Surg & Periodont, Fac Dent Ribeirao Preto, Sao Paulo - Brazil
Total Affiliations: 6
Document type: Journal article
Source: CLINICAL IMPLANT DENTISTRY AND RELATED RESEARCH; v. 13, n. 3, p. 224-230, 2011.
Web of Science Citations: 24

Background: Previous studies have pointed out that the mere elevation of the maxillary sinus membrane promotes bone formation without the use of augmentation materials. Purpose: This experimental study aimed at evaluating if the two-stage procedure for sinus floor augmentation could benefit from the use of a space-making device in order to increase the bone volume to enable later implant installation with good primary stability. Materials and Methods: Six male tufted capuchin primates (Cebus apella) were subjected to extraction of the three premolars and the first molar on both sides of the maxilla to create an edentulous area. The sinuses were opened using the lateral bone-wall window technique, and the membrane was elevated. One resorbable space-making device was inserted in each maxillary sinus, and the bone window was returned in place. The animals were euthanatized after 6 months, and biopsy blocks containing the whole maxillary sinus and surrounding soft tissues were prepared for ground sections. Results: The histological examination of the specimens showed bone formation in contact with both the schneiderian membrane and the device in most cases even when the device was displaced. The process of bone formation indicates that this technique is potentially useful for two-stage sinus floor augmentation. The lack of stabilization of the device within the sinus demands further improvement of space-makers for predictable bone augmentation. Conclusions: It is concluded that (1) the device used in this study did not trigger any important inflammatory reaction; (2) when the sinus membrane was elevated, bone formation was a constant finding; and (3) an ideal space-making device should be stable and elevate the membrane to ensure a maintained connection between the membrane and the secluded space. (AU)

FAPESP's process: 06/01322-8 - Development of an absorbable device for sinus floor augmentation: a histologic, histometric and RFA study in monkeys
Grantee:Luiz Antonio Salata
Support Opportunities: Regular Research Grants