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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

3q27 Aberrations in a Childhood Ovary Teratoma With Associated Malignant Germ Cell Component

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Author(s):
Brassesco, Maria Sol [1] ; Castro-Gamero, Angel Mauricio [2] ; Valera, Elvis Terci [1] ; Neder, Luciano [3] ; Elias, Jr., Jorge ; Tone, Luiz Gonzaga [1]
Total Authors: 6
Affiliation:
[1] Univ Sao Paulo, Fac Med Ribeirao Preto, Div Radiol, Dept Pediat, Div Pediat Oncol, Sao Paulo - Brazil
[2] Univ Sao Paulo, Fac Med Ribeirao Preto, Dept Genet, Sao Paulo - Brazil
[3] Univ Sao Paulo, Fac Med Ribeirao Preto, Dept Pathol, Sao Paulo - Brazil
Total Affiliations: 3
Document type: Journal article
Source: PEDIATRIC BLOOD & CANCER; v. 52, n. 3, p. 398-401, MAR 2009.
Web of Science Citations: 3
Abstract

Cytogenetic Studies of childhood ovary tumors have been poorly described. in the present article, the cytogenetic findings of an ovarian teratoma with malignant germ cell (yolk-sac) component occurring in an 8-year-old female are detailed. GTG-banding showed a karyotype of 46,XX, t(3;20)(q27;q13.3) {[}4]/46,XX, del3q27 {[}3]/46,XX {[}30]. Previous Studies have demonstrated common sites of loss of heterozygosity at 3q27-q28 region in different types of cancer, suggesting the presence of tumor Suppressor genes within this region. Pediatr Blood Cancer 2009;52:398-401. (C) 2008 Wiley-Liss, Inc. (AU)