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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Virulence Genes and Antimicrobial Resistance Profiles of Pasteurella multocida Strains Isolated from Rabbits in Brazil

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Porfida Ferreira, Thais Sebastiana [1] ; Felizardo, Maria Roberta [1] ; Sena de Gobbi, Debora Dirani [1] ; Gomes, Cleise Ribeiro [1] ; de Lima Nogueira Filsner, Pedro Henrique [1] ; Moreno, Marina [1] ; Paixao, Renata [1] ; Pereira, Jucelia de Jesus [1] ; Moreno, Andrea Micke [1, 2]
Total Authors: 9
[1] Univ Sao Paulo, Fac Med Vet & Zootecnia, Lab Sanidade Suina & Virol, Programa Epidemiol Expt Aplicada Zoonoses, Sao Paulo - Brazil
[2] VPS FMVZ USP, Lab Sanidade Suina & Virol, BR-05508270 Sao Paulo - Brazil
Total Affiliations: 2
Document type: Journal article
Web of Science Citations: 15

Pasteurella multocida is responsible for a wide range of diseases in domestic animals. In rabbits, the agent is related to nasal discharge, pneumonia, otitis media, pyometra, orchitis, abscess, and septicemia. One hundred and forty rabbits with respiratory diseases from four rabbitries in Sao Paulo State, Brazil were evaluated for the detection of P. multocida in their nasal cavities. A total of twenty-nine animals were positive to P. multocida isolation, and 46 strains were selected and characterized by means of biochemical tests and PCR. P. multocida strains were tested for capsular type, virulence genes, and resistance profile. A total of 45.6% (21/46) of isolates belonged to capsular type A, and 54.34% (25/46) of the isolates were untypeable. None of the strains harboured toxA or pfhA genes. The frequency of the other twenty genes tested was variable, and the data generated was used to build a dendrogram, showing the relatedness of strains, which were clustered according to origin. Resistance revealed to be more common against sulfonamides and cotrimoxazole, followed by erythromycin, penicillin, and amoxicillin. (AU)

FAPESP's process: 07/08592-3 - Isolation and characterization of p. multocida from cats and dogs
Grantee:Thaís Sebastiana Porfida Ferreira
Support type: Scholarships in Brazil - Doctorate
FAPESP's process: 07/03024-7 - Evaluation of serological and contamination profile of Pasteurella multocida in swine herds
Grantee:Andrea Micke Moreno
Support type: Regular Research Grants