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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Colistin Resistance in Escherichia coli and Salmonella enterica Strains Isolated from Swine in Brazil

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Author(s):
Morales, Adriano Savoia [1] ; de Araujo, Juliana Fragoso [1] ; Demoura Gomes, Vasco Tulio [1] ; Reis Costa, Adrienny Trindade [2] ; Rodrigues, Dalia dos Prazeres [3] ; Porfida Ferreira, Thais Sebastiana [1] ; Nogueira de Lima Filsner, Pedro Henrique [1] ; Felizardo, Maria Roberta [1] ; Moreno, Andrea Micke [1]
Total Authors: 9
Affiliation:
[1] Univ Sao Paulo, Lab Sanidade Suina & Virol, FMVZ, BR-05508270 Sao Paulo - Brazil
[2] Inst Pesquisas Vet Especializadas IPEVE, BR-30411119 Belo Horizonte, MG - Brazil
[3] Fiocruz MS, Lab Enterobacterias, BR-21040360 Rio De Janeiro, RJ - Brazil
Total Affiliations: 3
Document type: Journal article
Source: SCIENTIFIC WORLD JOURNAL; 2012.
Web of Science Citations: 18
Abstract

Reports about acquired resistance to colistin in different bacteria species are increasing, including E. coli of animal origin, but reports of resistance in wild S. enterica of different serotypes from swine are not found in the literature. Results obtained with one hundred and twenty-six E. coli strains from diseased swine and one hundred and twenty-four S. enterica strains from diseased and carrier swine showed a frequency of 6.3% and 21% of colistin-resistant strains, respectively. When comparing the disk diffusion test with the agar dilution test to evaluate the strains, it was confirmed that the disk diffusion test is not recommended to evaluate colistin resistance as described previously. The colistin MIC 90 and MIC 50 values obtained to E. coli were 0.25 mu g/mL and 0.5 mu g/mL, the MIC 90 and MIC 50 to S. enterica were 1 mu g/mL and 8 mu g/mL. Considering the importance of colistin in control of nosocomial human infections with Gram-negative multiresistant bacteria, and the large use of this drug in animal production, the colistin resistance prevalence in enterobacteriaceae of animal origin must be monitored more closely. (AU)

FAPESP's process: 09/14906-6 - Evaluation of resistance to colistin in E. coli strains from pigs through disk diffusion test and determination of minimal inhibitory concentration
Grantee:Adriano Savoia Morales
Support type: Scholarships in Brazil - Scientific Initiation
FAPESP's process: 09/14939-1 - Evaluation of resistance profile and presence of antimicrobial resistance codifying genes in Salmonella enterica subsp. enterica strains isolated from pigs
Grantee:Juliana Fragoso de Araújo
Support type: Scholarships in Brazil - Scientific Initiation