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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Effect of the bilateral hip bone density measurement on clinical practice in elderly subjects

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Author(s):
Lopes, Jaqueline B. [1] ; Danilevicius, Camille F. [1] ; Caparbo, Valeria F. [1] ; Takayama, Liliam [1] ; Carvalho, Jozelio Freire [1] ; Pereira, Rosa M. R. [1]
Total Authors: 6
Affiliation:
[1] Univ Sao Paulo, Bone Metab Lab, Div Rheumatol, Fac Med, Sao Paulo - Brazil
Total Affiliations: 1
Document type: Journal article
Source: MATURITAS; v. 63, n. 3, p. 257-260, JUL 20 2009.
Web of Science Citations: 2
Abstract

Objectives: The aim of this study was to determine whether the addition of the measurement of bilateral hip bone mineral density (BMD) has an impact on indications for osteoporosis (OP) treatment in community-dwelling elderly individuals, based on criteria from the National Osteoporosis Foundation (NOF). Methods: In total, 605 consecutive community-dwelling elderly individuals who were 65 years and older were evaluated. Dual energy X-ray absorptiometry was used to determine the lowest T-score in the lumbar spine + unilateral hip, the bilateral hips, and the lumbar spine + bilateral hips. Risk factors associated with the lowest T-score in these three conditions were applied to indicate treatment in accordance with NOF criteria. McNemar's test was used to assess the difference of adding bilateral hip BMD measurements. Results: There was a significant difference in the frequency of pharmacological indication using NOF criteria together with the lowest T-score for the three tests (72.8% for lumbar spine + bilateral hips and 71.2% for lumbar spine + unilateral hip; p=0.002). A higher frequency of treatment indication was also observed for lumbar spine + unilateral hip (71.2%) compared to bilateral hips (61.1%) (p<0.001). The discrepancies in treatment appeared to be more evident in women when analyzed by gender distribution. Conclusion: Our finding supports the theory that evaluation of the bilateral hips with the lumbar spine seems to be more sensitive measure for identifying patients with an osteoporosis treatment indication. Furthermore, despite the well-known artifact in the lumbar spine, this site should not be excluded when determining the indication for OP treatment in elderly people. (C) 2009 Elsevier Ireland Ltd. All rights reserved. (AU)

FAPESP's process: 03/09313-0 - Prevalence of osteoporosis, vertebral and non-vertebral fractures in a female population aged 65 or older in the Butantã area
Grantee:Rosa Maria Rodrigues Pereira
Support Opportunities: Regular Research Grants