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(Reference retrieved automatically from SciELO through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Synthesis and biological activity of three new 5a-hydroxy spirostanic brassinosteroid analogues

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Author(s):
Caridad R. Rodríguez [1] ; Yohan I. Villalobos [2] ; Esther A. Becerra [3] ; Francisco C. Manchado [4] ; Deysma C. Herrera [5] ; Marco A. T. Zullo [6]
Total Authors: 6
Affiliation:
[1] University of Havana. Faculty of Chemistry. Natural Products Laboratory - Cuba
[2] University of Havana. Faculty of Chemistry. Natural Products Laboratory - Cuba
[3] University of Havana. Faculty of Chemistry. Natural Products Laboratory - Cuba
[4] University of Havana. Faculty of Chemistry. Natural Products Laboratory - Cuba
[5] University of Havana. Faculty of Chemistry. Natural Products Laboratory - Cuba
[6] Instituto Agronômico. Laboratório de Fitoquímica - Brasil
Total Affiliations: 6
Document type: Journal article
Source: Journal of the Brazilian Chemical Society; v. 14, n. 3, p. 466-469, 2003-05-00.
Abstract

Three new spirostanic brassinosteroid analogues have been synthesized for the first time from diosgenin: (25R)-2alpha,3alpha-epoxy-5alpha-hydroxyspirostan-6-one (3), (25R)-2beta,3alpha,5alpha-trihydroxyspirostan-6-one (5) and (25R)-2beta-methoxy-3alpha,5alpha-dihydroxyspirostan-6-one (6). In the radish hypocotyl elongation and cotyledon expansion bioassay compound 3 showed plant growth promoting activity whereas 6 was shown to be phytotoxic. (AU)

FAPESP's process: 99/09687-0 - Caridad Robaina Rodriguez | University of Havana - Cuba
Grantee:Marco António Teixeira Zullo
Support Opportunities: Research Grants - Visiting Researcher Grant - International