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(Reference retrieved automatically from SciELO through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Physicochemical characterization of two deproteinized bovine xenografts

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Thais Accorsi-Mendonça ; Márcio Baltazar Conz ; Teresa Cristina Barros ; Lídia Ágata de Sena ; Glória de Almeida Soares ; José Mauro Granjeiro
Total Authors: 6
Document type: Journal article
Source: Brazilian Oral Research; v. 22, n. 1, p. 5-10, Mar. 2008.

Calcium phosphate salts, or more specifically hydroxyapatite, are products of great interest in the fields of medical and dental science due to their biocompatibility and osteoconduction property. Deproteinized xenografts are primarily constituted of natural apatites, sintered or not. Variations in the industrial process may affect physicochemical properties and, therefore, the biological outcome. The purpose of this work was to characterize the physical and chemical properties of deproteinized xenogenic biomaterials, Bio-Oss (Geistlich Biomaterials, Wolhuser, Switzerland) and Gen-Ox (Baumer S.A., Brazil), widely used as bone grafts. Scanning electron microscopy, infrared region spectroscopy, X-ray diffraction, thermogravimetry and degradation analysis were conducted. The results show that both materials presented porous granules, composed of crystalline hydroxyapatite without apparent presence of other phases. Bio-Oss presented greater dissolution in Tris-HCl than Gen-Ox in the degradation test, possibly due to the low crystallinity and the presence of organic residues. In conclusion, both commercial materials are hydroxyapatite compounds, Bio-Oss being less crystalline than Gen-Ox and, therefore, more prone to degradation. (AU)

FAPESP's process: 99/10655-5 - José Mauro Granjeiro | Faculdade de Odontologia de Bauru/USP - Brazil
Grantee:Mari Cleide Sogayar
Support type: Research Grants - Visiting Researcher Grant - Brazil
FAPESP's process: 01/10707-7 - Molecular bases of the control of cell proliferation and origin of neoplasms in the genomic and proteomic era
Grantee:Mari Cleide Sogayar
Support type: Research Projects - Thematic Grants