Schistosoma mansoni infection: an immune complex disease presenting with polyarthritis

Author(s)

Lapa, Aline Tamires ^[1] ; Appenzeller, Simone ^{[1, 2]} ; Bertolo, Manoel B. ^[1]

Affiliation

^[1] Univ Estadual Campinas, Rheumatol Unit, Dept Med, Fac Med Sci, Campinas, SP - Brazil

^[2] Univ Estadual Campinas, UNICAMP, Disciplina Reumatol, Dept Clin Med, Fac Ciencias Med, BR-13083970 Campinas, SP - Brazil

• Document type: Journal article
• Source: RHEUMATOLOGY INTERNATIONAL; v. 33, n. 5, p. 1341-1343, MAY 2013.
• Web of Science Citations: 3

Abstract

Schistosomiasis or bilharzia is a parasitic disease found in tropical countries. Most infections are subclinical but may progress to chronic form characterized most frequently by the presence of liver involvement and portal hypertension. We report a patient that presented chronic polyarthritis with positive rheumatoid factor. During investigation, increased liver enzymes, negative hepatitis serologies and signs of portal hypertension on an ultrasound examination raised suspicion of S. mansoni infection. We will discuss pathophysiology and clinical manifestations of S. mansoni infection with special attention to articular involvement. (AU)

• FAPESP's process: 09/06049-6 - Blood and cerebrospinal fluid biomarkers associated with structural and functional central nervous system abnormalities in Systemic lupus erythematosus
• Grantee: Simone Appenzeller
• Support Opportunities: Scholarships in Brazil - Young Researchers
• FAPESP's process: 09/16785-1 - Abnormal hipocampal signal in systemic lupus erythematosus
• Grantee: Aline Tamires Lapa
• Support Opportunities: Scholarships in Brazil - Scientific Initiation
• FAPESP's process: 08/02917-0 - Blood and cerebrospinal fluid biomarkers associated with structural and functional central nervous system abnormalities in systemic lupus erythematosus
• Grantee: Simone Appenzeller
• Support Opportunities: Research Grants - Young Investigators Grants