| Full text | |
| Author(s): |
Castillo Martinez, Fabio Andres
[1]
;
Balciunas, Eduardo Marcos
[1]
;
Manuel Salgado, Jose
[2]
;
Dominguez Gonzalez, Jose Manuel
[2]
;
Converti, Attilio
[3]
;
de Souza Oliveira, Ricardo Pinheiro
[1]
Total Authors: 6
|
| Affiliation: | [1] Univ Sao Paulo, Fac Pharmaceut Sci, Biochem & Pharmaceut Technol Dept, BR-05508900 Sao Paulo - Brazil
[2] Univ Vigo, Fac Sci, Dept Chem Engn, Orense 32004 - Spain
[3] Univ Genoa, Dept Civil Chem & Environm Engn, I-16145 Genoa - Italy
Total Affiliations: 3
|
| Document type: | Review article |
| Source: | TRENDS IN FOOD SCIENCE & TECHNOLOGY; v. 30, n. 1, p. 70-83, MAR 2013. |
| Web of Science Citations: | 221 |
| Abstract | |
Lactic acid was discovered in 1 780 by C.W. Scheele in sour milk, and in 1881 Fermi obtained lactic acid by fermentation, resulting in its industrial production. The yearly world lactic acid production is expected to reach 259,000 metric tons by the year 2012. The interest in lactic acid is related to many aspects, among which is its relatively high added-value. In addition, such a chemical is GRAS (Generally Recognized As Safe), being recognized as harmless by the United States Food and Drug Administration, has a market with great growth potential, can be alternatively produced by fermentation or chemical synthesis and can employ a large variety of different waste materials as substrates. Lactic acid has many applications. Its existence in the form of two stereoisomers does in fact make the application of one of them or of the racemic mixture of great concern in different fields. In particular, the food and pharmaceutical industries have a preference for the isomer L(+), the only one that can be metabolized by the human body; however, the chemical industry requires one of the pure isomers or a mixture of both, according to the application. This review describes biotechnological processes to obtain lactic acid from polymeric substrates such as starchy and lignocellulosic materials. Open challenges are related to the technological optimization of the fermentation process and product purification and recovery. In addition, the opportunities and difficulties associated with using raw materials for lactic acid production are discussed. (AU) | |
| FAPESP's process: | 11/14048-0 - Production of bacteriocin by Bifidobacterium lactis using milk whey as a substrate |
| Grantee: | Eduardo Marcos Balciunas |
| Support Opportunities: | Scholarships in Brazil - Master |