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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Seizures in systemic sclerosis

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Author(s):
Araujo, Fernando Glasner [1] ; Amaral, Tiago Nardi [2] ; Appenzeller, Simone [2] ; de Carvalho, Jozelio Freire [1]
Total Authors: 4
Affiliation:
[1] Univ Fed Bahia, Div Rheumatol, Hosp Univ Prof Edgard Santos, Sch Med Salvador, BR-41810080 Salvador, BA - Brazil
[2] Univ Estadual Campinas, Div Rheumatol, Fac Med Sci, Campinas, SP - Brazil
Total Affiliations: 2
Document type: Journal article
Source: RHEUMATOLOGY INTERNATIONAL; v. 33, n. 7, p. 1721-1724, JUL 2013.
Web of Science Citations: 3
Abstract

The aim of this study was to evaluate the frequency of seizures in systemic sclerosis (SSc) and to determine the clinical and laboratory features associated with their occurrence. Thirty-four SSc patients (ACR criteria) were analyzed by a standard interview, physical examination, and review of medical charts. Risk factors for seizures, clinical manifestations, associated co-morbidities and current treatment were evaluated. We identified 3 (8.8 %) SSc patients with seizures. A higher median age {[}61 (35-64) vs. 48 (27-71) years, p = 0.0005] and higher activity score {[}4.75 (4.5-5.0) vs. 2.5 (0-5-5) years, p = 0.006] were observed in SSc patients with seizures. No other clinical or laboratory feature was associated with the occurrence of seizure in this cohort. This study demonstrated a higher prevalence of seizures in SSc when compared to general population. Seizures were associated with older age and higher activity score in this cohort. (AU)

FAPESP's process: 09/06049-6 - Blood and cerebrospinal fluid biomarkers associated with structural and functional central nervous system abnormalities in Systemic lupus erythematosus
Grantee:Simone Appenzeller
Support type: Scholarships in Brazil - Young Researchers
FAPESP's process: 08/02917-0 - Blood and cerebrospinal fluid biomarkers associated with structural and functional central nervous system abnormalities in systemic lupus erythematosus
Grantee:Simone Appenzeller
Support type: Research Grants - Young Investigators Grants