| Full text | |
| Author(s): |
Martins, Larissa A.
[1]
;
Fogaca, Andrea C.
[1]
;
Tania Bijovsky, A.
[1]
;
Carballar-Lejarazu, Rebeca
[2]
;
Marinotti, Osvaldo
[2]
;
Cardoso, Andre F.
[1]
Total Authors: 6
|
| Affiliation: | [1] Univ Sao Paulo, Inst Ciencias Biomed, Dept Parasitol, BR-05508 Sao Paulo - Brazil
[2] Univ Calif Irvine, Dept Mol Biol & Biochem, Irvine, CA 92717 - USA
Total Affiliations: 2
|
| Document type: | Journal article |
| Source: | PLoS One; v. 8, n. 10 OCT 29 2013. |
| Web of Science Citations: | 6 |
| Abstract | |
Insect storage proteins accumulate at high levels during larval development of holometabolous insects. During metamorphosis they are degraded, supplying energy and amino acids for the completion of adult development. The genome of Culex quinquefasciatus contains eleven storage protein-coding genes. Their transcripts are more abundant in larvae than in pupae and in adults. In fact, only four of these genes are transcribed in adults, two of which in blood-fed adult females but not in adult males. Transcripts corresponding to all Cx. quinquefasciatus storage proteins were detected by RTPCR, while mass spectrometric analysis of larval and pupal proteins identified all storage proteins with the exception of one encoded by Cq LSP1.8. Our results indicate that the identified Cx. quinquefasciatus storage protein-coding genes are candidates for identifying regulatory sequences for the development of molecular tools for vector control. (AU) | |
| FAPESP's process: | 10/51241-0 - Culex quinquefasciatus: aspects of its physiology |
| Grantee: | Alcira Tania Bijovsky de Katzin |
| Support Opportunities: | Regular Research Grants |
| FAPESP's process: | 13/09211-4 - Culex quinquefasciatus: vitellogenin and their proteases |
| Grantee: | Alcira Tania Bijovsky de Katzin |
| Support Opportunities: | Regular Research Grants |