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(Reference retrieved automatically from SciELO through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Association between oxidative stress and nutritional status in the elderly

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Author(s):
Priscila Lucelia Moreira [1] ; Paulo Jose Fortes Villas Boas [2] ; Ana Lucia Anjos Ferreira [3]
Total Authors: 3
Affiliation:
[1] Universidade Estadual Paulista. Botucatu School of Medicine. Department of Clinical Medicine - Brasil
[2] Universidade Estadual Paulista. Botucatu School of Medicine. Department of Clinical Medicine - Brasil
[3] Universidade Estadual Paulista. Botucatu School of Medicine. Department of Clinical Medicine - Brasil
Total Affiliations: 3
Document type: Journal article
Source: Revista da Associação Médica Brasileira; v. 60, n. 1, p. 75-83, 2014-02-00.
Abstract

Ageing is a dynamic and progressive process that is characterized by the occurrence of morphological, biochemical, functional and psychological changes in the organism. The aim of the present article is to provide updated concepts on oxidative stress, covering its importance in aging, as well as nutritional status and supplementation with antioxidants (substances that prevent or attenuate oxidation of oxidizable substrates, such as lipids, proteins, carbohydrates and deoxyribonucleic acid) in the geriatric population. Evidence suggests that there is an inverse relationship between oxidative stress and nutritional status in elderly individuals. Although an increase in oxidative stress in chronic diseases associated with aging has been proven, such as Parkinson’s disease and Alzheimer’s disease, up to now there has been no consistent clinical evidence proving the efficiency of supplementation with antioxidants against oxidative stress. In this context, supplementation is not recommended. On the other hand, the elderly should be encouraged to eat antioxidant foods, such as fruits and vegetables. Maintaining a normal weight (body mass index between 23 and 28 Kg/m2) should also be stimulated. (AU)

FAPESP's process: 07/07455-2 - Time-course of oxidative stress induced by doxorubicin in rats: damage mechanism
Grantee:Ana Lucia do Anjos Ferreira
Support Opportunities: Regular Research Grants