Highlights in pathogenic fungal biofilms

Author(s)

Orlandi Sardi, Janaina De Cassia ^[1] ; Pitangui, Nayla De Souza ^[1] ; Rodriguez-Arellanes, Gabriela ^[2] ; Lucia Taylor, Maria ^[2] ; Fusco-Almeida, Ana Maria ^[1] ; Soares Mendes-Giannini, Maria Jose ^[1]

Affiliation

^[1] Univ Estadual Paulista UNESP, Fac Pharmaceut Sci, Lab Clin Mycol, Dept Clin Anal, Sao Paulo - Brazil

^[2] Univ Nacl Autonoma Mexico, Dept Microbiol & Parasitol, Fungal Immunol Lab, Mexico City 04510, DF - Mexico

• Document type: Journal article
• Source: REVISTA IBEROAMERICANA DE MICOLOGIA; v. 31, n. 1, p. 22-29, JAN 31 2014.
• Web of Science Citations: 46

Abstract

A wide variety of fungi have demonstrated the ability to colonize surfaces and form biofilms. Most studies on fungal biofilms have focused on Candida albicans and more recently, several authors have reported the involvement of other genera of yeasts and Candida species, as well as of filamentous fungi in the formation of biofilms, including: Cryptococcus neoformans, Cryptococcus gattii, Rhodotorula species, Aspergillus fumigatus, Malassezia pachydermatis, Histoplasma capsulatum, Paracoccidioides brasiliensis, Pneumocystis species, Coccidioides immitis, Fusarium species, Saccharomyces cerevisiae, Trichosporon asahii, Mucorales and Blastoschizomyces. There is a current interest in describing the particular characteristics of the biofilm formation by of these fungi. A major concern is the control of biofilms, requiring knowledge of the biofilm mechanisms. However, our knowledge of these microbial communities is limited, due to the complexity of these systems and metabolic interactions that remain unknown. This mini-review aims to highlight recently discovered fungal biofilms and to compare them with the current knowledge on biofilms. This manuscript is part of the series of works presented at the ``V International Workshop: Molecular genetic approaches to the study of human pathogenic fungi{''} (Oaxaca, Mexico, 2012). (C) 2013 Revista Iberoamericana de Micologia. Published by Elsevier Espana, S.L. All rights reserved. (AU)

• FAPESP's process: 11/12734-3 - Candida parapsilosis and C. orthopsilosis isolates from hemodialysis water. Application of proteomic and photocatalysis methodologies.
• Grantee: Regina Helena Pires
• Support Opportunities: Scholarships in Brazil - Post-Doctoral
• FAPESP's process: 03/02176-7 - Conservation and sustainable use of the diversity from Cerrado and Atlantic Forest: chemical diversity and prospecting for potential drugs - phase II
• Grantee: Vanderlan da Silva Bolzani
• Support Opportunities: BIOTA-FAPESP Program - Thematic Grants
• FAPESP's process: 04/07932-7 - Search for potential antitumoral, antioxidant, antiinflammatory, antidiabetic, acetylcholinesterase and mieloperoxidase inhibitory natural compounds from Cerrado and Atlantic Forest
• Grantee: Dulce Helena Siqueira Silva
• Support Opportunities: BIOTA-FAPESP Program - Thematic Grants
• FAPESP's process: 12/01270-9 - Candida parapsilosis and C. orthopsilosis isolates from hemodialysis water: application of proteomic and photocatalysis methodologies
• Grantee: Maria José Soares Mendes Giannini
• Support Opportunities: Regular Research Grants