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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Overview of the taxonomy and of the major secondary metabolites and their biological activities related to human health of the Laurencia complex (Ceramiales, Rhodophyta) from Brazil

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Author(s):
Fujii, Mutue T. [1] ; Cassano, Valeria ; Stein, Erika M. [2] ; Carvalho, Luciana R. [1]
Total Authors: 4
Affiliation:
[1] Inst Bot, Nucl Pesquisa Ficol, BR-04301902 Sao Paulo - Brazil
[2] Univ Sao Paulo, Dept Bot, Programa Posgrad, BR-05508 Sao Paulo - Brazil
Total Affiliations: 2
Document type: Journal article
Source: REVISTA BRASILEIRA DE FARMACOGNOSIA-BRAZILIAN JOURNAL OF PHARMACOGNOSY; v. 21, n. 2, p. 268-282, MAR-APR 2011.
Web of Science Citations: 30
Abstract

In Brazil, the Laurencia complex is represented by twenty taxa: Laurencia s.s. with twelve species, Palisada with four species (including Chondrophycus furcatus now that the proposal of its transference to Palisada is in process), and Osmundea and Yuzurua with two species each. The majority of the Brazilian species of the Laurencia complex have been phylogenetically analyzed by 54 rbcL sequences, including five other Rhodomelacean species as outgroups. The analysis showed that the Laurencia complex is monophyletic with high posterior probability value. The complex was separated into five clades, corresponding to the genera: Chondrophycus, Laurencia, Osmundea, Palisada, and Yuzurua. A bibliographical survey of the terpenoids produced by Brazilian species showed that only six species of Laurencia and five of Palisada (including C. furcatcus) have been submitted to chemical analysis with 48 terpenoids (47 sesquiterpenes and one triterpene) isolated. No diterpenes were found. Of the total, 23 sesquiterpenes belong to the bisabolane class and eighteen to the chamigrene type, whose biochemical precursor is bisabolane, two are derived from lauranes and four are triquinols. Despite the considerable number of known terpenes and their ecological and pharmacological importance, few experimental biological studies have been performed. In this review, only bioactivities related to human health were considered. (AU)

FAPESP's process: 10/52244-2 - Diversity and phylogenetic relationships of marine benthic algae: the Laurencia complex (Rhodophyta) in the Atlantic coasts of tropical and subtropical regions
Grantee:Valéria Cassano
Support type: Regular Research Grants
FAPESP's process: 10/50193-1 - Marine algae as source of metabolites of economical impact
Grantee:Pio Colepicolo Neto
Support type: BIOTA-FAPESP Program - Thematic Grants
FAPESP's process: 08/07775-0 - Evaluation of Biological activities of extracts from red algae Laurencia (Rhodomelaceae, Ceramiales)
Grantee:Erika Mattos Stein
Support type: Scholarships in Brazil - Master