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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Dietary glycemic load, glycemic index, and refined grains intake are associated with reduced beta-cell function in prediabetic Japanese migrants

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Sartorelli, Daniela Saes [1] ; Franco, Laercio Joel [1] ; Damiao, Renata [2] ; Gimeno, Suely [3] ; Cardoso, Marly Augusto [4] ; Gouvea Ferreira, Sandra Roberta [3, 4] ; Gr, Japanese-Brazilian Diabet Study
Total Authors: 7
[1] Univ Sao Paulo, Fac Med Ribeirao Preto, Dept Social Med, Ribeirao Preto, SP - Brazil
[2] Univ Fed Triangulo Mineiro, Dept Nutr, Uberaba, MG - Brazil
[3] Univ Fed Sao Paulo, Dept Prevent Med, Sao Paulo - Brazil
[4] Univ Sao Paulo, Dept Nutr, Fac Saude Publ, BR-09500900 Sao Paulo - Brazil
Total Affiliations: 4
Document type: Journal article
Source: Arquivos Brasileiros de Endocrinologia e Metabologia; v. 53, n. 4, p. 429-434, JUN 2009.
Web of Science Citations: 4

Objective: To investigate the association between carbohydrate intakes and beta-cell function (HOMA-beta) in Japanese-Brazilians with impaired glucose tolerance (IGT). Methods: Dietary intakes were assessed by a validated food frequency questionnaire in a cross-sectional survey carried out in 2000. The associations between diet and HOMA-beta were verified in 270 newly diagnosed IGT in multiple linear regression models. Results: The mean (SD) age was 58 (11) years and the mean HOMA-beta was 65 (47). The glycemic load was inversely associated with HOMA-beta, beta 1 -0.140 (95% CI = -1.044; - 0.078), p = 0.023. The inverse association was also observed for refined grains intakes: -0.186 (95% CI = - 0.4862; -0.058), p = 0.012. After adjustments for body mass index, the glycemic index was inversely associated with HOMA-beta: -0.1246 (95% CI = -2.2482, -0.0257), p < 0.001. Conclusions: These data suggested that dietary glycemic load, glycemic index, and refined grains intakes are associated with reduced beta-cell function, and the quality of dietary carbohydrates may be relevant for maintaining beta-cell function among individuals with IGT. Arq Bras Endocrinol Metab. 2009; 53(4): 429-34. (AU)

FAPESP's process: 98/04178-7 - Diabetes mellitus and Associate Diseases in the Japanese-Brazilian community from Bauru - Fase II
Grantee:Sandra Roberta Gouvea Ferreira Vivolo
Support type: Research Projects - Thematic Grants