Demonstration of Plasmid-Mediated Drug Resistance in Mycobacterium abscessus

Author(s)

Matsumoto, Cristianne Kayoko ^[1] ; Martins Bispo, Paulo Jose ^[2] ; Santin, Katiane ^[2] ; Nogueira, Christiane Lourenco ^[1] ; Leao, Sylvia Cardoso ^[1]

Affiliation

^[1] Univ Fed Sao Paulo, Dept Microbiol Imunol & Parasitol, Sao Paulo - Brazil

^[2] Univ Fed Sao Paulo, Dept Oftalmol, Lab Microbiol Ocular, Sao Paulo - Brazil

• Document type: Journal article
• Source: Journal of Clinical Microbiology; v. 52, n. 5, p. 1727-1729, MAY 2014.
• Web of Science Citations: 3

Abstract

Plasmid-mediated kanamycin resistance was detected in a strain of Mycobacterium abscessus subsp. bolletii responsible for a nationwide epidemic of surgical infections in Brazil. The plasmid did not influence susceptibility to tobramycin, streptomycin, trimethoprim-sulfamethoxazole, clarithromycin, or ciprofloxacin. Plasmid-mediated drug resistance has not been described so far in mycobacteria. (AU)

• FAPESP's process: 12/13763-0 - Taxonomic characterization of mycobacteria belonging to Mycobacterium chelonae-M.abscessus group without conclusive species identification
• Grantee: Christiane Lourenço Nogueira
• Support Opportunities: Scholarships in Brazil - Doctorate
• FAPESP's process: 11/18326-4 - Mycobacteria and extrachromosomal elements: molecular characterization and biotechnological applications
• Grantee: Sylvia Luisa Pincherle Cardoso Leão
• Support Opportunities: Research Projects - Thematic Grants