Suplementação nutricional e exercício para otimizar o desempenho: foco nas respostas individuais e um passo para a nutrição esportiva personalizada

• Processo: 16/50438-0
• Modalidade de apoio: Auxílio à Pesquisa - Jovens Pesquisadores
• Vigência: 01 de abril de 2017 - 31 de março de 2022
• Área do conhecimento: Ciências da Saúde - Educação Física
• Convênio/Acordo: Newton Fund, com FAPESP como instituição parceira no Brasil
• Pesquisador responsável: Bryan Saunders
• Beneficiário: Bryan Saunders
• Instituição Sede: Faculdade de Medicina (FM). Universidade de São Paulo (USP). São Paulo , SP, Brasil
• Auxílios(s) vinculado(s): 21/06836-0 - Placebo em esporte e exercício: prevalência, condicionamento e placebo aberto, AP.JP2; 18/13124-3 - Efeitos placebos: da saúde ao esporte, AV.EXT; 18/03861-0 - Placebo em nutrição esportiva: um estudo de prova de princípio envolvendo suplementação de cafeína, PUB.ART
• Bolsa(s) vinculada(s): 20/12036-3 - A influência do polimorfismo CYP1A2 sobre as respostas fisiológicas e de desempenho após a suplementação aguda de cafeína, BP.DD; 20/02391-0 - Efeito do consumo habitual de cafeína nas respostas individuais à suplementação aguda de cafeína, BP.IC; 19/20614-0 - Influência do polimorfismo em MCT1 e MCT4 na performance e respostas sanguíneas frente a um teste de ciclismo de 1-km contrarrelógio em atletas recreacionais, BP.IC; + mais bolsas vinculadas 19/06140-5 - Efeitos agudos da ingestão de b-alanina sobre os mecanismos reguladores do conteúdo de carnosina muscular, BP.MS; 18/01594-5 - Respostas sanguíneas e musculares à suplementação de bicarbonato de sódio e subsequente desempenho do exercício, BP.MS; 17/15314-1 - A influência do polimorfismo CYP1A2 sobre as respostas fisiológicas e de desempenho após a suplementação aguda de cafeína, BP.MS; 17/24841-5 - Suplementação de bicarbonato de sódio no desempenho de um contrarrelógio de ciclismo de 1-km, BP.IC; 17/04973-4 - Suplementação nutricional e exercício para otimizar o desempenho: foco nas respostas individuais e um passo para a nutrição esportiva personalizada, BP.JP - menos bolsas vinculadas
• Assunto(s): Ciências da nutrição e do esporte Suplementação alimentar Nutrição esportiva Fisiologia do exercício Desempenho atlético
• Palavra(s)-Chave do Pesquisador: Ergogenic Aids | Exercise Physiology | Metabolic Responses | Nutritional Supplementation | Personlised Nutrition
• Publicação FAPESP: https://media.fapesp.br/bv/uploads/pdfs/fapesp_uk_C0aIR3B_152_152.pdf

Resumo

Ergogênicos são suplementos nutricionais predominantemente prescritos com o objetivo de melhorar a capacidade de exercício e o desempenho, embora possam ainda promover benefícios para a saúde. O bicarbonato de sódio, a cafeína e a β-alanina tornaram-se suplementos essencialmente utilizados em associação ao treinamento de atletas de elite, profissionais e recreacionais, e sua eficácia na melhoria da capacidade de exercício e desempenho é apoiada por evidências científicas substanciais. No entanto a variabilidade nas respostas à mesma levou a uma recente sugestão de que a suplementação poderia não ser benéfica para todos os indivíduos. Diante do exposto, torna-se relevante determinar as fontes de variação ínter- e intra-individuais em resposta a suplementação e se estas podem ser utilizadas para otimizar estratégias de administração de suplementos em prol da melhora do desempenho durante o exercício. O estudo 1 irá avaliar a consistência nas respostas à suplementação de bicarbonato de sódio, revelando a viabilidade de individualizar o momento da ingestão. No estudo 2 iremos determinar se cápsulas entéricas podem otimizar a dose-resposta da suplementação de bicarbonato de sódio e aliviar alguns dos efeitos colaterais associados à essa estratégia. O estudo 3 irá elucidar a consistência nas respostas a suplementação com bicarbonato de sódio frente ao exercício, enquanto o estudo 4 irá determinar se as alterações na atividade dos transportadores musculares (MCT1, MCT4, NHE) estão relacionadas com as alterações nas concentrações de bicarbonato de sódio na circulação. O estudo 5 irá determinar a cinética das respostas sanguíneas seguida da ingestão de cafeína entre indivíduos com diferentes fenótipos para o metabolismo de cafeína, enquanto o estudo 6 irá determinar o papel do fenótipo sobre a eficácia da suplementação de cafeína para o exercício. O estudo 7 irá determinar as respostas metabólicas agudas da suplementação de beta-alanina no período basal e após 4 semanas de suplementação, enquanto o estudo 8 irá determinar se uma sessão aguda de exercício também influencia as mesmas respostas metabólicas. Acreditamos que os resultados obtidos neste projeto abrangente terão impactos significativos e duradouros sobre o entendimento das respostas metabólicas agudas à suplementação e ao exercício, e irão desempenhar um papel fundamental na otimização da suplementação nutricional para atletas, bem como direcionar futuros trabalhos na área. (AU)

Publicações científicas

(58)

(Referências obtidas automaticamente do Web of Science e do SciELO, por meio da informação sobre o financiamento pela FAPESP e o número do processo correspondente, incluída na publicação pelos autores)

NABUCO, LARA LIMA; SAUNDERS, BRYAN; SOUSA DA SILVA, RENATO ANDRE; MOLINA, GUILHERME ECKHARDT; GONCALVES REIS, CAIO EDUARDO. Caffeine Mouth Rinse Does Not Improve Time to Exhaustion in Male Trained Cyclists. INTERNATIONAL JOURNAL OF SPORT NUTRITION AND EXERCISE METABOLISM, v. 31, n. 5, p. 412-419, SEP 2021. (16/50438-0)

SCHWARTZ, JULIANO; OH, PAUL; TAKITO, MONICA Y.; SAUNDERS, BRYAN; DOLAN, EIMEAR; FRANCHINI, EMERSON; RHODES, RYAN E.; BREDIN, SHANNON S. D.; COELHO, JOSYE P.; DOS SANTOS, PEDRO; et al. Translation, Cultural Adaptation, and Reproducibility of the Physical Activity Readiness Questionnaire for Everyone (PAR-Q+): The Brazilian Portuguese Version. FRONTIERS IN CARDIOVASCULAR MEDICINE, v. 8, JUL 26 2021. (19/26899-6, 16/50438-0, 19/05616-6)

SAUNDERS, BRYAN; DE OLIVEIRA, LUANA FARIAS; DOLAN, EIMEAR; DURKALEC-MICHALSKI, KRZYSZTOF; MCNAUGHTON, LARS; ARTIOLI, GUILHERME GIANNINI; SWINTON, PAUL ALAN. Sodium bicarbonate supplementation and the female athlete: A brief commentary with small scale systematic review and meta-analysis. European Journal of Sport Science, FEB 2021. (19/25032-9, 16/50438-0, 19/26899-6, 19/05616-6)

MILIONI, FABIO; BONETTI DE POLI, RODRIGO ARAUJO; SAUNDERS, BRYAN; GUALANO, BRUNO; DA ROCHA, ALISSON L.; RAMOS DA SILVA, ADELINO SANCHEZ; GUERRERO MULLER, PAULO DE TARSO; ZAGATTO, ALESSANDRO MOURA. Effect of beta-alanine supplementation during high-intensity interval training on repeated sprint ability performance and neuromuscular fatigue. Journal of Applied Physiology, v. 127, n. 6, p. 1599-1610, DEC 2019. (16/11076-6, 16/50438-0, 16/17836-2, 16/02683-6)

BASSINELLO, DIOGO; PAINELLI, VITOR DE SALLES; DOLAN, EIMEAR; LIXANDRAO, MANOEL; CAJUEIRO, MONIQUE; DE CAPITANI, MARIANA; SAUNDERS, BRYAN; SALE, CRAIG; ARTIOLI, GUILHERME G.; GUALANO, BRUNO; et al. Beta-alanine supplementation improves isometric, but not isotonic or isokinetic strength endurance in recreationally strength-trained young men. Amino Acids, v. 51, n. 1, p. 27-37, JAN 2019. (13/14746-4, 17/04973-4, 16/50438-0, 16/10993-5, 15/23072-2, 13/04806-0, 15/11328-2)

DA SILVA, RAFAEL PIRES; DE OLIVEIRA, LUANA FARIAS; SAUNDERS, BRYAN; KRATZ, CAROLINE DE ANDRADE; PAINELLI, VITOR DE SALLES; SILVA, VINICIUS DA EIRA; BOUZAS MARINS, JOAO CARLOS; FRANCHINI, EMERSON; GUALANO, BRUNO; ARTIOLI, GUILHERME GIANNINI. Effects of -alanine and sodium bicarbonate supplementation on the estimated energy system contribution during high-intensity intermittent exercise. Amino Acids, v. 51, n. 1, p. 83-96, JAN 2019. (13/14746-4, 16/50438-0, 12/13026-5, 14/11948-8, 13/04806-0)

DOLAN, E.; SAUNDERS, B.; DANTAS, W. S.; MURAI, I. H.; ROSCHEL, H.; ARTIOLI, G. G.; HARRIS, R.; BICUDO, J. E. P. W.; SALE, C.; GUALANO, B.. A Comparative Study of Hummingbirds and Chickens Provides Mechanistic Insight on the Histidine Containing Dipeptide Role in Skeletal Muscle Metabolism. SCIENTIFIC REPORTS, v. 8, OCT 3 2018. (13/14746-4, 16/10993-5, 17/09635-0, 15/11328-2, 16/50438-0, 17/04973-4)

PAINELLI, VITOR DE SALLES; NEMEZIO, KLEINER MARCIO; PINTO, ANA JESSICA; FRANCHI, MARIANA; ANDRADE, ISABEL; RIANI, LUIZ AUGUSTO; SAUNDERS, BRYAN; SALE, CRAIG; HARRIS, ROGER CHARLES; GUALANO, BRUNO; et al. High-Intensity Interval Training Augments Muscle Carnosine in the Absence of Dietary Beta-alanine Intake. MEDICINE AND SCIENCE IN SPORTS AND EXERCISE, v. 50, n. 11, p. 2242-2252, NOV 2018. (14/11948-8, 13/04806-0, 13/14746-4, 16/50438-0)

FIGUEIREDO, NAYRA; QUEIROZ, MARCELA; FELICIO, FERNANDA P.; FERREIRA, JESSICA; GEROSA-NETO, JOSE; MOTA, JO AO F.; DA SILVA, CHRISTIELLY R.; GHEDINI, PAULO C.; SAUNDERS, BRYAN; PIMENTEL, GUSTAVO D.. Acute caffeine mouth rinsing does not improve 10-km running performance in CYP1A2 C-allele carriers. CLINICAL NUTRITION ESPEN, v. 42, p. 93-97, APR 2021. (16/50438-0)

PEACOCK, J.; SPARKS, S. A.; MIDDLEBROOK, I; HILTON, N. P.; TINNION, D.; LEACH, N.; SAUNDERS, B.; MCNAUGHTON, L. R.. Extraceullular buffer choice influences acid-base responses and gastrointestinal symptoms. RESEARCH IN SPORTS MEDICINE, MAR 2021. (16/50438-0)

SILVA DE SOUZA, RICARDO AUGUSTO; DA SILVA, ANDRE GUEDES; DE SOUZA, MAGDA FERREIRA; FERREIRA SOUZA, LILIANA KATARYNE; ROSCHEL, HAMILTON; DA SILVA, SANDRO FERNANDES; SAUNDERS, BRYAN. A Systematic Review of CrossFit (R) Workouts and Dietary and Supplementation Interventions to Guide Nutritional Strategies and Future Research in CrossFit (R). INTERNATIONAL JOURNAL OF SPORT NUTRITION AND EXERCISE METABOLISM, v. 31, n. 2, p. 187-205, MAR 2021. (16/50438-0, 19/22249-7)

GRGIC, JOZO; RODRIGUEZ, RAMON F.; GAROFOLINI, ALESSANDRO; SAUNDERS, BRYAN; BISHOP, DAVID J.; SCHOENFELD, BRAD J.; PEDISIC, ZELJKO. Effects of Sodium Bicarbonate Supplementation on Muscular Strength and Endurance: A Systematic Review and Meta-analysis. SPORTS MEDICINE, v. 50, n. 7, FEB 2020. (17/04973-4, 16/50438-0)

GRGIC, JOZO; PEDISIC, ZELJKO; SAUNDERS, BRYAN; ARTIOLI, GUILHERME G.; SCHOENFELD, BRAD J.; MCKENNA, MICHAEL J.; BISHOP, DAVID J.; KREIDER, RICHARD B.; STOUT, JEFFREY R.; KALMAN, DOUGLAS S.; et al. International Society of Sports Nutrition position stand: sodium bicarbonate and exercise performance. JOURNAL OF THE INTERNATIONAL SOCIETY OF SPORTS NUTRITION, v. 18, n. 1, SEP 9 2021. (16/50438-0)

BARRETO, G.; LOUREIRO, L. M. R.; REIS, C. E. G.; SAUNDERS, B.. Effects of caffeine chewing gum supplementation on exercise performance: A systematic review and meta-analysis. European Journal of Sport Science, v. N/A, p. 12-pg., 2022-03-16. (17/15314-1, 16/50438-0)

OLIVEIRA-JUNIOR, GERSIEL; PINTO, RAFAELA S.; SHIRLEY, MEGHAN K.; LONGMAN, DANIEL P.; KOEHLER, KARSTEN; SAUNDERS, BRYAN; ROSCHEL, HAMILTON; DOLAN, EIMEAR. The Skeletal Muscle Response to Energy Deficiency: A Life History Perspective. ADAPTIVE HUMAN BEHAVIOR AND PHYSIOLOGY, v. 8, n. 1, p. 16-pg., 2022-01-24. (19/05616-6, 19/26899-6, 20/07540-4, 16/50438-0)

SAITO, TIEMI; BARRETO, GABRIEL; SAUNDERS, BRYAN; GUALANO, BRUNO. Is Open-Label Placebo a New Ergogenic Aid? A Commentary on Existing Studies and Guidelines for Future Research. SPORTS MEDICINE, v. 50, n. 7, APR 2020. (17/15314-1, 17/04973-4, 16/50438-0)

CICCONETTI, FRANCO; SESTILI, PIERO; MADIAI, VALERIA; ALBERTINI, MARIA CRISTINA; CAMPANELLA, LUIGI; COPPARI, SOFIA; FRATERNALE, DANIELE; SAUNDERS, BRYAN; TEODORI, LAURA. Extracellular pH, osmolarity, temperature and humidity could discourage SARS-CoV-2 cell docking and propagation via intercellular signaling pathways. PeerJ, v. 9, OCT 11 2021. (16/50438-0)

DE OLIVEIRA, LUANA FARIAS; DOLAN, EIMEAR; SWINTON, PAUL A.; DURKALEC-MICHALSKI, KRZYSZTOF; ARTIOLI, GUILHERME G.; MCNAUGHTON, LARS R.; SAUNDERS, BRYAN. xtracellular Buffering Supplements to Improve Exercise Capacity and Performance: A Comprehensive Systematic Review and Meta-analysi. SPORTS MEDICINE, v. 52, n. 3, OCT 2021. (19/25032-9, 19/26899-6, 16/50438-0)

PERIM, PEDRO; GOBBI, NATHAN; DUARTE, BRENO; FARIAS DE OLIVEIRA, LUANA; COSTA, LUIZ AUGUSTO RIANI; SALE, CRAIG; GUALANO, BRUNO; DOLAN, EIMEAR; SAUNDERS, BRYAN. Beta-alanine did not improve high-intensity performance throughout simulated road cycling. European Journal of Sport Science, v. 22, n. 8, p. 10-pg., 2021-06-16. (16/50438-0, 19/07497-4, 19/05616-6, 19/06140-5, 18/01594-5, 17/13552-2, 16/17391-0)

DANTAS, MATHEUS; BARBOZA-NETO, RUI; GUARDIEIRO, NATALIA MENDES; DE SA PINTO, ANA LUCIA; GUALANO, BRUNO; SAUNDERS, BRYAN. A cloth facemask increased ratings of perceived exertion and reduced affect, without affecting sprint or muscular performance. RESEARCH IN SPORTS MEDICINE, DEC 2021. (16/50438-0)

BARRETO, GABRIEL; GRECCO, BEATRIZ; MEROLA, PIETRO; GONCALVES REIS, CAIO EDUARDO; GUALANO, BRUNO; SAUNDERS, BRYAN. Novel insights on caffeine supplementation, CYP1A2 genotype, physiological responses and exercise performance. EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY, v. 121, n. 3, JAN 2021. (17/15314-1, 17/13552-2, 20/02391-0, 16/50438-0)

BARRETO, GABRIEL; DE OLIVEIRA, LUANA FARIAS; SAITO, TIEMI; KLOSTERHOFF, RAFAEL; PERIM, PEDRO; DOLAN, EIMEAR; PEREIRA, ROSA MARIA R.; CAMPOS-FERRAZ, PATRICIA; LIMA, FERNANDA R.; SAUNDERS, BRYAN. Reduced Endurance Capacity and Suboptimal Energy Availability in Top-Level Female Cyclists. INTERNATIONAL JOURNAL OF SPORTS PHYSIOLOGY AND PERFORMANCE, v. 16, n. 8, p. 1194-1203, AUG 2021. (18/01594-5, 17/15314-1, 16/50438-0, 19/05616-6, 19/26899-6)

DE OLIVEIRA, LUANA FARIAS; SAUNDERS, BRYAN; ARTIOLI, GUILHERME GIANNINI. Is Bypassing the Stomach a Means to Optimize Sodium Bicarbonate Supplementation? A Case Study With a Postbariatric Surgery Individual. INTERNATIONAL JOURNAL OF SPORT NUTRITION AND EXERCISE METABOLISM, v. 28, n. 6, p. 660-663, NOV 2018. (14/11948-8, 16/50438-0)

MENDES, GUILHERME FALCAO; REIS, CAIO EDUARDO GONCALVES; NAKANO, EDUARDO YOSHIO; DA COSTA, TERESA HELENA MACEDO; SAUNDERS, BRYAN; ZANDONADI, RENATA PUPPIN. Translation and Validation of the Caffeine Expectancy Questionnaire in Brazil (CaffEQ-BR). NUTRIENTS, v. 12, n. 8, p. 19-pg., 2020-08-01. (16/50438-0)

SAUNDERS, BRYAN; GOBBI, NATHAN. Location location location: muscle glycogen content and endurance exercise. JOURNAL OF PHYSIOLOGY-LONDON, v. 599, n. 1, p. 3-pg., 2020-10-12. (19/07497-4, 16/50438-0)

GUARDIEIRO, NATALIA MENDES; BARRETO, GABRIEL; MARTICORENA, FELIPE MIGUEL; OLIVEIRA, TAMIRES NUNES; DE OLIVEIRA, LUANA FARIAS; PINTO, ANA LUCIA DE SA; DO PRADO, DANILO MARCELO LEITE; SAUNDERS, BRYAN; GUALANO, BRUNO. A Cloth Facemask Causes No Major Respiratory or Cardiovascular Perturbations During Moderate to Heavy Exercise. JOURNAL OF PHYSICAL ACTIVITY & HEALTH, v. 20, n. 1, p. 10-pg., 2023-01-01. (21/05847-8, 16/50438-0, 20/12036-3, 17/13552-2, 21/06836-0, 20/04368-6)

MARTICORENA, FELIPE MIGUEL; BARRETO, GABRIEL CASTANHO; GUARDIEIRO, NATALIA MENDES; ESTEVES, GABRIEL PERRI; OLIVEIRA, TAMIRES NUNES; DE OLIVEIRA, LUANA FARIAS; PINTO, ANA LUCIA DE SA; RIANI, LUIZ; PRADO, DANILO MENDES; SAUNDERS, BRYAN; et al. Performing moderate to severe activity is safe and tolerable for healthy youth while wearing a cloth facemask. PLoS One, v. 18, n. 3, p. 11-pg., 2023-03-06. (21/05847-8, 16/50438-0, 20/12036-3, 17/13552-2, 20/07860-9, 20/04368-6)

BERJISIAN, ERFAN; MCGAWLEY, KERRY; SAUNDERS, BRYAN; DOMINGUEZ, RAUL; KOOZEHCHIAN, MAJID S.; COUTINHO DE OLIVEIRA, CAIO VICTOR; RAFIEI, RAMIN; MIRAFTABI, HOSSEIN; SARSHIN, AMIR; NADERI, ALIREZA. Acute effects of beetroot juice and caffeine co-ingestion during a team-sport-specific intermittent exercise test in semi-professional soccer players: a randomized, double-blind, placebo-controlled study. BMC SPORTS SCIENCE MEDICINE AND REHABILITATION, v. 14, n. 1, p. 11-pg., 2022-03-29. (16/50438-0)

SAUNDERS, BRYAN; DE OLIVEIRA, LUANA FARIAS; DOLAN, EIMEAR; DURKALEC-MICHALSKI, KRZYSZTOF; MCNAUGHTON, LARS; ARTIOLI, GUILHERME GIANNINI; SWINTON, PAUL ALAN. Sodium bicarbonate supplementation and the female athlete: A brief commentary with small scale systematic review and meta-analysis. European Journal of Sport Science, v. 22, n. 5, p. 10-pg., 2021-02-27. (19/25032-9, 16/50438-0, 19/26899-6, 19/05616-6)

SAUNDERS, BRYAN; MCNAUGHTON, LARS R.; SIEGLER, JASON. Editorial: Nutritional Buffering Strategies to Improve Exercise Capacity and Performance. FRONTIERS IN NUTRITION, v. 8, p. 2-pg., 2021-03-25. (16/50438-0)

SAUNDERS, BRYAN; SAITO, TIEMI; KLOSTERHOFF, RAFAEL; DE OLIVEIRA, LUANA FARIAS; BARRETO, GABRIEL; PERIM, PEDRO; PINTO, ANA JESSICA; LIMA, FERNANDA; DE SAPINTO, ANA LUCIA; GUALANO, BRUNO. "I put it in my head that the supplement would help me": Open-placebo improves exercise performance in female cyclists. PLoS One, v. 14, n. 9, p. 16-pg., 2019-09-24. (17/15314-1, 16/50438-0, 15/26937-4, 17/04973-4, 18/01594-5)

GUIMARAES, RODRIGO DOS SANTOS; DE MORAIS JUNIOR, ALCIDES CORREA; SCHINCAGLIA, RAQUEL MACHADO; SAUNDERS, BRYAN; PIMENTEL, GUSTAVO DUARTE; MOTA, JOAO FELIPE. Sodium Bicarbonate Supplementation Does Not Improve Running Anaerobic Sprint Test Performance in Semiprofessional Adolescent Soccer Players. INTERNATIONAL JOURNAL OF SPORT NUTRITION AND EXERCISE METABOLISM, v. 30, n. 5, p. 330-337, SEP 2020. (16/50438-0, 17/04973-4)

ESTEVES, GABRIEL PERRI; SWINTON, PAUL; SALE, CRAIG; JAMES, RUTH M.; ARTIOLI, GUILHERME GIANNINI; ROSCHEL, HAMILTON; GUALANO, BRUNO; SAUNDERS, BRYAN; DOLAN, EIMEAR. Individual Participant Data Meta-Analysis Provides No Evidence of Intervention Response Variation in Individuals Supplementing With Beta-Alanine. INTERNATIONAL JOURNAL OF SPORT NUTRITION AND EXERCISE METABOLISM, v. 31, n. 4, p. 305-313, JUL 2021. (19/05616-6, 20/07860-9, 19/25032-9, 16/50438-0, 19/26899-6)

PERIM, PEDRO; GOBBI, NATHAN; DUARTE, BRENO; FARIAS DE OLIVEIRA, LUANA; COSTA, LUIZ AUGUSTO RIANI; SALE, CRAIG; GUALANO, BRUNO; DOLAN, EIMEAR; SAUNDERS, BRYAN. Beta-alanine did not improve high-intensity performance throughout simulated road cycling. European Journal of Sport Science, JUN 2021. (19/07497-4, 17/13552-2, 18/01594-5, 19/06140-5, 16/17391-0, 16/50438-0, 19/05616-6)

RIBEIRO, RAFAEL; DUARTE, BRENO; DA SILVA, ANDRE GUEDES; RAMOS, GUILHERME PASSOS; PICANCO, ANDREIA ROSSI; PENNA, EDUARDO MACEDO; COSWIG, VICTOR; BARBALHO, MATHEUS; GENTIL, PAULO; GUALANO, BRUNO; et al. Short-Duration Beta-Alanine Supplementation Did Not Prevent the Detrimental Effects of an Intense Preparatory Period on Exercise Capacity in Top-Level Female Footballers. FRONTIERS IN NUTRITION, v. 7, APR 21 2020. (19/06140-5, 16/50438-0, 17/04973-4)

SAUNDERS, BRYAN; SAITO, TIEMI; KLOSTERHOFF, RAFAEL; DE OLIVEIRA, LUANA FARIAS; BARRETO, GABRIEL; PERIM, PEDRO; PINTO, ANA JESSICA; LIMA, FERNANDA; DE SAPINTO, ANA LUCIA; GUALANO, BRUNO. ``I put it in my head that the supplement would help me{''}: Open-placebo improves exercise performance in female cyclists. PLoS One, v. 14, n. 9, SEP 24 2019. (15/26937-4, 18/01594-5, 17/04973-4, 17/15314-1, 16/50438-0)

MARTICORENA, FELIPE MIGUEL; CARVALHO, ARTHUR; DE OLIVEIRA, LUANA FARIAS; DOLAN, EIMEAR; GUALANO, BRUNO; SWINTON, PAUL; SAUNDERS, BRYAN. Nonplacebo Controls to Determine the Magnitude of Ergogenic Interventions: A Systematic Review and Meta-analysis. MEDICINE AND SCIENCE IN SPORTS AND EXERCISE, v. 53, n. 8, p. 1766-1777, AUG 2021. (19/26899-6, 16/50438-0, 19/20614-0)

PEACOCK, J.; SPARKS, S. A.; MIDDLEBROOK, I; HILTON, N. P.; TINNION, D.; LEACH, N.; SAUNDERS, B.; MCNAUGHTON, L. R.. Extraceullular buffer choice influences acid-base responses and gastrointestinal symptoms. RESEARCH IN SPORTS MEDICINE, v. 29, n. 6, p. 12-pg., 2021-03-12. (16/50438-0)

PERIM, PEDRO; MARTICORENA, FELIPE MIGUEL; RIBEIRO, FELIPE; BARRETO, GABRIEL; GOBBI, NATHAN; KERKSICK, CHAD; DOLAN, EIMEAR; SAUNDERS, BRYAN. Can the Skeletal Muscle Carnosine Response to Beta-Alanine Supplementation Be Optimized?. FRONTIERS IN NUTRITION, v. 6, AUG 27 2019. (18/01594-5, 17/15314-1, 17/04973-4, 16/50438-0, 19/05616-6, 18/19981-5)

DOLAN, EIMEAR; SAUNDERS, BRYAN; HARRIS, ROGER CHARLES; BICUDO, JOSE EDUARDO PEREIRA WILKEN; BISHOP, DAVID JOHN; SALE, CRAIG; GUALANO, BRUNO. Comparative physiology investigations support a role for histidine-containing dipeptides in intracellular acid base regulation of skeletal muscle. COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY A-MOLECULAR & INTEGRATIVE PHYSIOLOGY, v. 234, p. 77-86, AUG 2019. (13/14746-4, 17/04973-4, 16/50438-0, 17/09635-0, 15/11328-2)

DOLAN, EIMEAR; WARREN, DANIEL E.; HARRIS, ROGER C.; SALE, CRAIG; GUALANO, BRUNO; SAUNDERS, BRYAN. Skeletal muscle histidine-containing dipeptide contents are increased in freshwater turtles (C. picta bellii) with cold-acclimation. COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY A-MOLECULAR & INTEGRATIVE PHYSIOLOGY, v. 262, DEC 2021. (19/26899-6, 17/13552-2, 16/50438-0, 19/05616-6)

JONES, REBECCA L.; STELLINGWERFF, TRENT; SWINTON, PAUL; ARTIOLI, GUILHERME GIANNINI; SAUNDERS, BRYAN; SALE, CRAIG. Warm-Up Intensity Does Not Affect the Ergogenic Effect of Sodium Bicarbonate in Adult Men. INTERNATIONAL JOURNAL OF SPORT NUTRITION AND EXERCISE METABOLISM, v. 31, n. 6, p. 482-489, NOV 2021. (19/25032-9, 14/11948-8, 16/50438-0)

CARVALHO, ARTHUR; MARTICORENA, FELIPE MIGUEL; GRECCO, BEATRIZ HELENA; BARRETO, GABRIEL; SAUNDERS, BRYAN. Can I Have My Coffee and Drink It? A Systematic Review and Meta-analysis to Determine Whether Habitual Caffeine Consumption Affects the Ergogenic Effect of Caffeine. SPORTS MEDICINE, v. N/A, p. 12-pg., 2022-05-10. (20/12036-3, 21/05847-8, 20/02391-0, 16/50438-0, 19/20614-0, 21/06836-0)

SAUNDERS, BRYAN; FRANCHI, MARIANA; DE OLIVEIRA, LUANA FARIAS; SILVA, VINICIUS DA EIRA; DA SILVA, RAFAEL PIRES; PAINELLI, VITOR DE SALLES; RIANI COSTA, LUIZ AUGUSTO; SALE, CRAIG; HARRIS, ROGER CHARLES; ROSCHEL, HAMILTON; et al. 24-Week beta-alanine ingestion does not affect muscle taurine or clinical blood parameters in healthy males. EUROPEAN JOURNAL OF NUTRITION, v. 59, n. 1, p. 57-65, FEB 2020. (13/14746-4, 17/04973-4, 16/50438-0, 12/13026-5, 14/11948-8, 13/04806-0, 15/22686-7)

DOLAN, EIMEAR; SWINTON, PAUL A.; PAINELLI, VITOR DE SALLES; HEMINGWAY, BENEDICT STEPHENS; MAZZOLANI, BRUNA; SMAIRA, FABIANA INFANTE; SAUNDERS, BRYAN; ARTIOLI, GUILHERME G.; GUALANO, BRUNO. A Systematic Risk Assessment and Meta-Analysis on the Use of Oral beta-Alanine Supplementation. ADVANCES IN NUTRITION, v. 10, n. 3, p. 452-463, MAY 2019. (13/14746-4, 17/04973-4, 16/50438-0, 17/09635-0, 14/11948-8, 13/04806-0, 15/11328-2)

SWINTON, PAUL A.; HEMINGWAY, BEN STEPHENS; SAUNDERS, BRYAN; GUALANO, BRUNO; DOLAN, EIMEAR. A Statistical Framework to Interpret Individual Response to Intervention : Paving the Way for Personalized Nutrition and Exercise Prescription. FRONTIERS IN NUTRITION, v. 5, MAY 28 2018. (13/14746-4, 17/04973-4, 16/50438-0, 17/09635-0, 15/11328-2)

HEIBEL, ANDRE B.; PERIM, PEDRO H. L.; OLIVEIRA, LUANA F.; MCNAUGHTON, LARS R.; SAUNDERS, BRYAN. Time to Optimize Supplementation: Modifying Factors Influencing the Individual Responses to Extracellular Buffering Agents. FRONTIERS IN NUTRITION, v. 5, MAY 8 2018. (16/17391-0, 17/04973-4, 16/50438-0)

RIBEIRO, FELIPE; LONGOBARDI, IGOR; PERIM, PEDRO; DUARTE, BRENO; FERREIRA, PEDRO; GUALANO, BRUNO; ROSCHEL, HAMILTON; SAUNDERS, BRYAN. iming of Creatine Supplementation around Exercise: A Real Concern. NUTRIENTS, v. 13, n. 8, AUG 2021. (19/06140-5, 16/50438-0, 18/19981-5)

KARAYIGIT, RACI; NADERI, ALIREZA; SAUNDERS, BRYAN; FORBES, SCOTT C.; COSO, JUAN DEL; BERJISIAN, ERFAN; YILDIRIM, ULAS CAN; SUZUKI, KATSUHIKO. Combined but Not Isolated Ingestion of Caffeine and Taurine Improves Wingate Sprint Performance in Female Team-Sport Athletes Habituated to Caffeine. SPORTS, v. 9, n. 12, DEC 2021. (16/50438-0)

NEHME, RAFAELA; DE BRANCO, FLAVIA M. S.; VIEIRA, PUBLIO F.; GUIMARAES, ANA VITORIA C.; GOMES, GEDERSON K.; TEIXEIRA, GABRIELA P.; RODRIGUES, PEDRO H.; DE CASTRO JUNIOR, LEONARDO M.; PUGA, GUILHERME M.; SAUNDERS, BRYAN; et al. Single and Serial Carbohydrate Mouth Rinsing Do Not Improve Yo-Yo Intermittent Recovery Test Performance in Soccer Players. INTERNATIONAL JOURNAL OF SPORT NUTRITION AND EXERCISE METABOLISM, v. 32, n. 1, p. 22-29, JAN 2022. (16/50438-0)

DE AMORIM ROCHA, PEDRO LUCAS; CALDEIRA LIMA, ANNA LUISA; SAUNDERS, BRYAN; GONCALVES REIS, CAIO EDUARDO. Development of a Caffeine Content Table for Foods, Drinks, Medications and Supplements Typically Consumed by the Brazilian Population. NUTRIENTS, v. 14, n. 20, p. 14-pg., 2022-10-01. (16/50438-0, 21/06836-0)

DOLAN, EIMEAR; SWINTON, PAUL A.; PAINELLI, VITOR DE SALLES; HEMINGWAY, BENEDICT STEPHENS; MAZZOLANI, BRUNA; SMAIRA, FABIANA INFANTE; SAUNDERS, BRYAN; ARTIOLI, GUILHERME G.; GUALANO, BRUNO. A Systematic Risk Assessment and Meta-Analysis on the Use of Oral β-Alanine Supplementation. ADVANCES IN NUTRITION, v. 10, n. 3, p. 12-pg., 2019-05-01. (13/04806-0, 17/09635-0, 13/14746-4, 16/50438-0, 14/11948-8, 17/04973-4, 15/11328-2)

SAUNDERS, BRYAN; VIRGILE, ADAM; ELLIOTT-SALE, KIRSTY JAYNE; ARTIOLI, GUILHERME GIANNINI; SWINTON, PAUL A.; DOLAN, EIMEAR; ROSCHEL, HAMILTON; SALE, CRAIG; GUALANO, BRUNO. Infographic. A systematic review and meta-analysis of the effect of beta-alanine supplementation on exercise capacity and performance. BRITISH JOURNAL OF SPORTS MEDICINE, v. 54, n. 15, p. 2-pg., 2020-08-01. (17/04973-4, 16/50438-0, 15/11328-2, 14/11948-8)

CARVALHO, ARTHUR; DUARTE, BRENO; ELLIOTT-SALE, KIRSTY JAYNE; SAUNDERS, BRYAN. Directions for Future Studies to Determine Dietary Nitrate Efficacy in Female Athletes. TRANSLATIONAL JOURNAL OF THE AMERICAN COLLEGE OF SPORTS MEDICINE, v. 8, n. 4, p. 3-pg., 2023-01-01. (21/06836-0, 21/13799-3, 16/50438-0, 19/06140-5)

NEWBURY, JOSH W.; SAUNDERS, BRYAN; GOUGH, LEWIS A.. Evening Caffeine Did Not Improve 100-m Swimming Time Trials Performed 60 Min Post-Ingestion or the Next Morning After Sleep. INTERNATIONAL JOURNAL OF SPORT NUTRITION AND EXERCISE METABOLISM, v. 32, n. 6, p. 9-pg., 2022-11-01. (21/06836-0, 16/50438-0)

MENDES, GUILHERME FALCAO; REIS, CAIO EDUARDO GONCALVES; NAKANO, EDUARDO YOSHIO; SPINELI, HIGOR; BARRETO, GABRIEL; NORONHA, NATALIA YUMI; WATANABE, LIGIA MORIGUCHI; NONINO, CARLA BARBOSA; DE ARAUJO, GUSTAVO GOMES; SAUNDERS, BRYAN; et al. Can the Brazilian Caffeine Expectancy Questionnaires Differentiate the CYP1A2 and ADORA2A Gene Polymorphisms?-An Exploratory Study with Brazilian Athletes. NUTRIENTS, v. 14, n. 16, p. 12-pg., 2022-08-01. (18/24069-3, 20/12036-3, 21/06836-0, 16/50438-0, 20/08687-9)

DE OLIVEIRA, LUANA FARIAS; SAUNDERS, BRYAN; YAMAGUCHI, GUILHERME; SWINTON, PAUL; ARTIOLI, GUILHERME GIANNINI. Is Individualization of Sodium Bicarbonate Ingestion Based on Time to Peak Necessary?. MEDICINE AND SCIENCE IN SPORTS AND EXERCISE, v. 52, n. 8, p. 1801-1808, AUG 2020. (16/50438-0, 17/04973-4)

NADERI, ALIREZA; GOBBI, NATHAN; ALI, AJMOL; BERJISIAN, ERFAN; HAMIDVAND, AMIN; FORBES, SCOTT C.; KOOZEHCHIAN, MAJID S.; KARAYIGIT, RACI; SAUNDERS, BRYAN. Carbohydrates and Endurance Exercise: A Narrative Review of a Food First Approach. NUTRIENTS, v. 15, n. 6, p. 19-pg., 2023-03-01. (21/06836-0, 16/50438-0, 19/07497-4)