INCT 2014: biodiversidade e produtos naturais

• Processo: 14/50926-0
• Modalidade de apoio: Auxílio à Pesquisa - Programa BIOTA - Temático
• Vigência: 01 de julho de 2017 - 30 de junho de 2024
• Área do conhecimento: Ciências Exatas e da Terra - Química
• Convênio/Acordo: CNPq - INCTs
• Pesquisador responsável: Vanderlan da Silva Bolzani
• Beneficiário: Vanderlan da Silva Bolzani
• Instituição Sede: Instituto de Química (IQ). Universidade Estadual Paulista (UNESP). Campus de Araraquara. Araraquara , SP, Brasil
• Pesquisadores principais:( Atuais ): Ian Castro-Gamboa ; Leticia Veras Costa Lotufo
• Pesquisadores principais:( Anteriores ): Alberto Jose Cavalheiro ; Maria José Soares Mendes Giannini
• Auxílios(s) vinculado(s): 23/09497-7 - American Society of Pharmacognosy 2023 Annual Meeting, AR.EXT; 18/50025-3 - Green analytical chemistry applied to the investigation of agro industrial wastes generated in Brazil and Australia, AP.R SPRINT
• Bolsa(s) vinculada(s): 23/00454-3 - Avaliação de novos inibidores duais de histona desacetilases e metaloproteinases em linhagens celulares de glioblastoma, BP.IC; 23/02775-1 - Prospecção de novas substâncias com potencial anticâncer em bactérias isoladas da ascídia Trididemnum maragogi, BP.IC
• Assunto(s): Biodiversidade Produtos naturais Metabólitos secundários Pesquisa básica Desenvolvimento de produtos Sustentabilidade Micro-organismos
• Palavra(s)-Chave do Pesquisador: Quimica
• Publicação FAPESP: https://media.fapesp.br/bv/uploads/pdfs/Brazilian_biodiversity...future_syWaC2Z_55_56.pdf

Resumo

O projeto delineado está centrado nos pilares de sustentação da Ciência, Tecnologia e Inovação, que norteiam as sociedades do conhecimento: (a) pesquisa básica e aplicada de excelência; (b) formação de recursos humanos em biodiversidade e produtos naturais; (c) colaboração com o setor empresarial para desenvolvimento tecnológico a partir das inovações em produtos naturais; (d) difusão do conhecimento sobre a biodiversidade e produtos naturais bioativos para o ensino médio e outros segmentos da sociedade; (e) contribuição nas ações de políticas públicas de conservação e uso sustentável da biodiversidade. Dentro destes fundamentos, o Instituto Nacional de Ciência & Tecnologia (INCTBioNat) foi criado para mapear e catalogar de forma organizada todas as informações sobre os metabólitos secundários detectados e/ou isolados de organismos de nossa rica biodiversidade, fundamental para o avanço de pesquisa em química de produtos naturais do Brasil. O conhecimento e uso sustentável da biodiversidade brasileira foi preconizado no documento Política Nacional da Biodiversidade, editado pela Secretaria de Biodiversidade e Florestas (SBF), Ministério do Meio Ambiente (MMA), em 2002 e tem prioridade para o desenvolvimento nacional. A criação de uma rede nacional de pesquisa para mapeamento químico e biológico das espécies terrestres, marinhas e de microrganismos da nossa biodiversidade constitui-se numa estratégia racional para a seleção de substâncias ativas mais promissoras para posterior estudos farmacológicos e toxicológicos visando moléculas protótipos. Para atingir tais metas, o ICNTBioNat reúne pesquisadores de excelência e pesquisadores jovens e talentosos que iniciam suas carreiras em universidades federais e estaduais de vários estados da federação, englobando todas as regiões do Brasil. Toda equipe atuará de forma colaborativa e multidisciplinar objetivando o fortalecimento de uma área de pesquisa e inovação estratégica para o Brasil, através de uma rede de laboratórios de excelência em produtos naturais para exploração e uso sustentável da rica biodiversidade brasileira. (AU)

Publicações científicas

(93)

(Referências obtidas automaticamente do Web of Science e do SciELO, por meio da informação sobre o financiamento pela FAPESP e o número do processo correspondente, incluída na publicação pelos autores)

MAIARA S. BORGES; CAROLINA R. BIASETTO; VANESSA M. CHAPLA; SAMAD N. EBRAHIMI; MAYRA F. COSTA; VANDERLAN S. BOLZANI; ANGELA R. ARAUJO. Assessment of Novel C-4 Methylated Tetraketide by HPLC-SPE-TT in Saccharicola sp., an Endophytic Fungus in Eugenia jambolana Lam.. Journal of the Brazilian Chemical Society, v. 30, n. 3, p. 522-527, 2019-03-00. (14/50926-0, 13/07600-3)

DANIELE RODRIGUES DE LIMA; MARIA GLEIZIANE DE ARAÚJO FRANCA; FÁTIMA DE CÁSSIA EVANGELISTA DE OLIVEIRA; CLÁUDIA DO Ó PESSOA; ALBERTO JOSÉ CAVALHEIRO; MARIA GORETTI DE VASCONCELOS SILVA. METABOLIC PROFILING AND CYTOTOXIC ACTIVITY OF METHANOL EXTRACTS FROM CHAMAECRISTA DUCKEANA (P. BEZERRA & A. FERN.) H. S. IRWIN & BARNEBY (LEGUMINOSAE, CAESALPINIOIDEAE). Química Nova, v. 45, n. 7, p. 803-806, 2022-09-26. (13/07600-3, 14/50926-0)

FUNARI, CRISTIANO SOLEO; CAVALHEIRO, ALBERTO JOSE; CARNEIRO, RENATO LAJARIM. Coupled monolithic columns as an alternative for the use of viscous ethanol-water mobile phases on chromatographic fingerprinting complex samples. REVISTA BRASILEIRA DE FARMACOGNOSIA-BRAZILIAN JOURNAL OF PHARMACOGNOSY, v. 28, n. 3, p. 261-266, MAY-JUN 2018. (14/50926-0, 13/07600-3, 10/18840-7)

FERREIRA SANTOS, NATACHA CARVALHO; VALLI, MARILIA; BOLZANI, VANDERLAN DA SILVA. A brief overview on Brazilian women in chemistry. Pure and Applied Chemistry, v. 91, n. 4, SI, p. 743-749, APR 2019. (14/50926-0, 13/07600-3)

RIBEIRO, SABRINA M.; FRATUCELLI, ERICK D. O.; BUENO, PAULA C. P.; DE CASTRO, V, MARLENE KELLY; FRANCISCO, AMANDA ALCALA; CAVALHEIRO, ALBERTO JOSE; KLEIN, I, MARLISE. Antimicrobial and antibiofilm activities of Casearia sylvestris extracts from distinct Brazilian biomes against Streptococcus mutans and Candida albicans. BMC COMPLEMENTARY AND ALTERNATIVE MEDICINE, v. 19, n. 1, NOV 12 2019. (13/07600-3, 14/50926-0, 11/21440-3, 12/21921-4, 17/07408-6)

XIMENES, VALDECIR FARIAS; MORGON, NELSON HENRIQUE; DE SOUZA, AGUINALDO ROBINSON. Solvent-dependent inversion of circular dichroism signal in naproxen: An unusual effect!. CHIRALITY, v. 30, n. 9, p. 1049-1053, SEP 2018. (14/50926-0, 15/22338-9, 16/20549-5)

DANUELLO, AMANDA; DE CASTRO, ROGERIO CARDOSO; PILON, ALAN CESAR; PIRES BUENO, PAULA CAROLINA; PIVATTO, MARCOS; VIEIRA JUNIOR, GERARDO MAGELA; CARVALHO, FLAVIO ALEXANDRE; ODA, FERNANDO BOMBARDA; PEREZ, CONSUELO JAVIERA; LOPES, NORBERTO PEPORINE; et al. Fragmentation study of clerodane diterpenes from Casearia species by tandem mass spectrometry (quadrupole time-of-flight and ion trap). RAPID COMMUNICATIONS IN MASS SPECTROMETRY, v. 34, n. 3, SI, MAY 2020. (11/21440-3, 16/13292-8, 17/19702-6, 13/07600-3, 14/50926-0)

SCUPINARI, TAMIRES; RUSSO, HELENA MANNOCHIO; SABINO FERRARI, ANNA BEATRIZ; BOLZANI, VANDERLAN SILVA; DIAS, WALDIR PEREIRA; NUNES, ESTELA DE OLIVEIRA; HOFFMANN-CAMPO, CLARA BEATRIZ; ZERAIK, MARIA LUIZA. Crotalaria spectabilis as a source of pyrrolizidine alkaloids and phenolic compounds: HPLC-MS/MS dereplication and monocrotaline quantification of seed and leaf extracts. Phytochemical Analysis, v. 31, n. 6, MAY 2020. (13/07600-3, 14/50926-0, 16/16970-7)

VIEIRA, NATALIA CAROLINA; CORTELO, PATRICIA CARDOSO; CASTRO-GAMBOA, IAN. Rapid qualitative profiling of metabolites present in Fusarium solani, a rhizospheric fungus derived from Senna spectabilis, using GC/MS and UPLC-QTOF/MSE techniques assisted by UNIFI information system. EUROPEAN JOURNAL OF MASS SPECTROMETRY, v. 26, n. 4, MAY 2020. (14/50926-0, 13/07600-3)

BIASETTO, CAROLINA R.; SOMENSI, ANDRESSA; SORDI, RENATA; CHAPLA, VANESSA M.; EBRAHIMI, SAMAD N.; SILVA, GERALDO H.; TELES, HELDER L.; BOLZANI, VANDERLAN DA S.; YOUNG, MARIA CLAUDIA M.; PFENNING, LUDWIG H.; et al. The new koninginins T-U from Phomopsis stipata, an endophytic fungus isolated from Styrax camporum Pohl. PHYTOCHEMISTRY LETTERS, v. 36, p. 106-110, APR 2020. (14/50926-0, 13/07600-3, 03/02176-7)

SALDIVAR-GONZALEZ, FERNANDA I.; VALLI, MARILIA; ANDRICOPULO, ADRIANO D.; BOLZANI, VANDERLAN DA SILVA; MEDINA-FRANCO, JOSE L.. Chemical Space and Diversity of the NuBBE Database: A Chemoinformatic Characterization. JOURNAL OF CHEMICAL INFORMATION AND MODELING, v. 59, n. 1, p. 74-85, JAN 2019. (14/50926-0, 13/07600-3)

WOLF, VANESSA GONCALVES; BONACORSI, CIBELE; GONCALVES RADDI, MARIA STELLA; DA FONSECA, LUIZ MARCOS; XIMENES, VALDECIR FARIAS. Octyl gallate, a food additive with potential beneficial properties to treat Helicobacter pylori infection. FOOD & FUNCTION, v. 8, n. 7, p. 2500-2511, JUL 1 2017. (14/50926-0, 15/21693-0)

BICALHO, KEYLLA U.; SANTONI, MARIANA M.; ARENDT, PHILIPP; ZANELLI, CLESLEI F.; FURLAN, MAYSA; GOOSSENS, ALAIN; POLLIER, JACOB. CYP712K4 Catalyzes the C-29 Oxidation of Friedelin in the Maytenus ilicifolia Quinone Methide Triterpenoid Biosynthesis Pathway. Plant and Cell Physiology, v. 60, n. 11, p. 2510-2522, NOV 2019. (14/50926-0, 13/07600-3, 15/25175-3, 17/10911-1, 16/16970-7)

DE ALMEIDA, LARISSA COSTA; BAUERMEISTER, ANELIZE; REZENDE-TEIXEIRA, PAULA; DOS SANTOS, EVELYNE ALVES; BERALDO DE MORAES, LUIZ ALBERTO; MACHADO-NETO, JOAO AGOSTINHO; COSTA-LOTUFO, LETICIA VERAS. Pradimicin-IRD exhibits antineoplastic effects by inducing DNA damage in colon cancer cells. Biochemical Pharmacology, v. 168, p. 38-47, OCT 2019. (17/17648-4, 15/17177-6, 18/17595-0, 17/24993-0, 14/50926-0)

NUNES, WILHAN DONIZETE GONCALVES; RUSSO, HELENA MANNOCHIO; BOLZANI, VANDERLAN DA SILVA; CAIRES, FLAVIO JUNIOR. Thermal characterization and compounds identification of commercialStevia rebaudianaBertoni sweeteners and thermal degradation products at high temperatures by TG-DSC, IR and LC-MS/MS. JOURNAL OF THERMAL ANALYSIS AND CALORIMETRY, AUG 2020. (18/24378-6, 14/50926-0, 13/07600-3, 16/16970-7)

BERTOZO, LUIZA DE CARVALHO; NETO, ERNESTO TAVARES; DE OLIVEIRA, LEANDRO CRISTANTE; XIMENES, VALDECIR FARIAS. Oxidative Alteration of Trp-214 and Lys-199 in Human Serum Albumin Increases Binding Affinity with Phenylbutazone: A Combined Experimental and Computational Investigation. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, v. 19, n. 10, OCT 2018. (14/50926-0, 16/20549-5, 16/22014-1)

TORREZAN, GUILHERME SILVA; POLAQUINI, CARLOS ROBERTO; LIMA, MARCELO FREITAS; REGASINI, LUIS OCTAVIO. Use of glycerol, waste glycerol from biodiesel production and other protic solvents in bioactive alpha, beta-unsaturated ketones synthesis. SUSTAINABLE CHEMISTRY AND PHARMACY, v. 16, JUN 2020. (18/15083-2, 09/53989-4, 14/50926-0, 14/18330-0)

DE VASCONCELOS, DEBORA NALIATI; LIMA, ANGELICA NAKAGAWA; PHILOT, ERIC ALLISON; SCOTT, ANA LIGIA; FERREIRA BOZA, IZABELLE AMORIM; DE SOUZA, AGUINALDO ROBINSON; MORGON, NELSON HENRIQUE; XIMENES, VALDECIR FARIAS. Methyl divanillate: redox properties and binding affinity with albumin of an antioxidant and potential NADPH oxidase inhibitor. RSC ADVANCES, v. 9, n. 35, p. 19983-19992, JUL 1 2019. (14/50926-0, 16/20549-5, 16/22014-1)

VALLI, MARILIA; BOLZANI, VANDERLAN S.. Natural Products: Perspectives and Challenges for use of Brazilian Plant Species in the Bioeconomy. Anais da Academia Brasileira de Ciências, v. 91, n. 3, 2019. (03/02176-7, 14/50926-0, 13/07600-3)

AGUINALDO ROBINSON DE SOUZA; IZABELLE AMORIM FERREIRA BOZA; VALDECIR FARIAS XIMENES; MAURÍCIO IKEDA YOGUIN; MARÍA-JOSÉ DÁVILA-RODRIGUEZ; NELSON HENRIQUE MORGON; IGNEZ CARACELLI. ELUCIDAÇÃO DA QUIRALIDADE INDUZIDA NA MOLÉCULA DANSILGLICINA NA COMPLEXAÇÃO COM A PROTEÍNA ALBUMINA DO SORO HUMANO (HSA). Química Nova, v. 42, n. 2, p. 135-142, 2019-02-00. (14/50926-0, 16/20549-5, 15/22338-9)

MARQUES, BEATRIZ C.; SANTOS, MARIANA B.; ANSELMO, DAIANE B.; MONTEIRO, DIEGO A.; GOMES, ELENI; SAIKI, MARILIA F. C.; RAHAL, PAULA; ROSALEN, PEDRO L.; SARDI, JANAINA C. O.; REGASINI, LUIS O.. Methoxychalcones: Effect of Methoxyl Group on the Antifungal Antibacterial and Antiproliferative Activities. Medicinal Chemistry, v. 16, n. 7, p. 881-891, 2020. (14/18330-0, 17/09245-7, 14/18577-5, 09/53989-4, 18/15083-2, 16/08084-7, 14/50926-0)

SOUSA, IRAN DA L.; HEERDT, GABRIEL; XIMENES, VALDECIR F.; DE SOUZA, AGUINALDO R.; MORGON, NELSON H.. TD-DFT Analysis of the Dissymmetry Factor in Camphor. Journal of the Brazilian Chemical Society, v. 31, n. 3, p. 613-618, MAR 2020. (14/50926-0, 16/20549-5, 15/22338-9, 16/04963-6, 19/12294-5)

ASSE JUNIOR, LEONARDO RANDER; KRONENBERGER, THALES; MAGALHAES SERAFIM, MATEUS SA; SOUSA, YAMARA VIANA; FRANCO, ISABELLA DRUMOND; VALLI, MARILIA; BOLZANI, VANDERLAN DA SILVA; MONTEIRO, GUSTAVO CLARO; BRUNO PRATES, JOAO LUCAS; KROON, ERNA GEESSIEN; et al. Virtual screening of antibacterial compounds by similarity search of Enoyl-ACP reductase (FabI) inhibitors. Future Medicinal Chemistry, v. 12, n. 1, p. 51-68, JAN 2020. (19/05967-3, 14/50926-0, 13/07600-3)

DOS SANTOS, MARIANA BASTOS; MARQUES, BEATRIZ CARVALHO; AYUSSO, GABRIELA MIRANDA; ROCHA GARCIA, MAYARA APARECIDA; PARACATU, LUANA CHIQUETTO; PAULI, IVANI; BOLZANI, VANDERLAN SILVA; ANDRICOPULO, ADRIANO DEFINI; XIMENES, VALDECIR FARIAS; ZERAIK, MARIA LUIZA; et al. Chalcones and their B-aryl analogues as myeloperoxidase inhibitors: In silico, in vitro and ex vivo investigations. BIOORGANIC CHEMISTRY, v. 110, MAY 2021. (16/00580-5, 14/18330-0, 09/53989-4, 18/15083-2, 14/50926-0)

FRANCA, MARIA G. A.; CAVALHEIRO, ALBERTO J.; SILVA, MARIA G. V.. A Comprehensive LC-DAD-QTOF-MS Method for Dereplication of Bioactive Compounds in Senna Extracts. REVISTA BRASILEIRA DE FARMACOGNOSIA-BRAZILIAN JOURNAL OF PHARMACOGNOSY, v. 31, n. 1, p. 32-39, FEB 2021. (13/07600-3, 14/50926-0)

FERRARI, ANNA BEATRIZ SABINO; MARCHEAFAVE, GUSTAVO GALO; MANNOCHIO-RUSSO, HELENA; BOLZANI, VANDERLAN DA SILVA; ZIED, DIEGO CUNHA; SCARMINIO, IEDA SPACINO; ZERAIK, MARIA LUIZA. Chemical composition and chromatographic fingerprint of three strains of Agaricus subrufescens cultivated with handmade and commercial supplements. Food Chemistry, v. 363, NOV 30 2021. (14/50926-0, 13/07600-3)

BIM-JUNIOR, ODAIR; GAGLIERI, CAROLINE; BEDRAN-RUSSO, ANA K.; BUENO-SILVA, BRUNO; BANNACH, GILBERT; FREM, REGINA; XIMENES, VALDECIR FARIAS; LISBOA-FILHO, PAULO N.. MOF-Based Erodible System for On-Demand Release of Bioactive Flavonoid at the Polymer-Tissue Interface. ACS BIOMATERIALS SCIENCE & ENGINEERING, v. 6, n. 8, p. 4539-4550, AUG 2020. (17/08820-8, 14/50926-0, 18/02186-8)

ASSIRATI, JULIA; RINALDO, DANIEL; RABELO, SARITA CANDIDA; BOLZANI, VANDERLAN DA SILVA; HILDER, EMILY FRANCES; FUNARI, CRISTIANO SOLEO. A green, simplified, and efficient experimental setup for a high-throughput screening of agri-food by-products - From polar to nonpolar metabolites in sugarcane solid residues. Journal of Chromatography A, v. 1634, DEC 20 2020. (18/50025-3, 17/06216-6, 18/09886-5, 18/01786-1, 14/50926-0)

DE TOLEDO, LUCIANI GASPAR; DOS SANTOS RAMOS, MATHEUS APARECIDO; DA SILVA, PATRICIA BENTO; RODERO, CAMILA FERNANDA; GOMES, VERIDIANA DE SA; DA SILVA, ANDERSON NORONHA; PAVAN, FERNANDO ROGERIO; DA SILVA, ISABEL CRISTIANE; ODA, FERNANDO BOMBARDA; FLUMIGNAN, DANILO LUIS; et al. Improved in vitro and in vivo Anti-Candida albicans Activity of Cymbopogon nardus Essential Oil by Its Incorporation into a Microemulsion System. INTERNATIONAL JOURNAL OF NANOMEDICINE, v. 15, p. 10481-10497, 2020. (20/13057-4, 16/08559-5, 14/50926-0, 15/23959-7)

REGINALDO, FERNANDA P. SANTOS; FREIRE, RAFAEL; COSTA, ISABELLY C. M.; DA SILVA, IVANICE BEZERRA; ROQUE, ALAN DE ARAUJO; HALLWASS, FERNANDO; CASTRO-GAMBOA, IAN; FETT-NETO, ARTHUR GERMANO; CAVALHEIRO, ALBERTO J.; GIORDANI, RAQUEL B.. NMR-based metabolite profiling of Selaginella convoluta in different hydration states and the unprecedented occurrence of anabasine in lycophytes. PHYTOCHEMISTRY LETTERS, v. 43, p. 75-79, JUN 2021. (14/50926-0)

DA SILVA, GISELLE LOPES; CAMPIDELI, MARIANA BORDIN; SABINO FERRARI, ANNA BEATRIZ; MANNOCHIO-RUSSO, HELENA; FRAIGE, KARINA; DAMETTO, ALESSANDRA CRISTINA; BOLZANI, VANDERLAN DA SILVA; ZERAIK, MARIA LUIZA. In vitro antiglycation and antioxidant properties of Eugenia pyriformis leaves and fruits. NATURAL PRODUCT RESEARCH, NOV 2021. (13/07600-3, 14/50926-0)

DA SILVA, JAFF RIBEIRO; DE CERQUEIRA E SILVA, MARIANA BARROS; PHILADELPHO, BIANE OLIVEIRA; DE SOUZA, VICTORIA CRUZ; MACHADO DOS SANTOS, JOHNNIE ELTON; CASTILHO, MARCELO SANTOS; FERREIRA, EDERLAN DE SOUZA; CILLI, EDUARDO MAFFUD. PyrGF and GSTLN peptides enhance pravastatin's inhibition of 3-hydroxy-3-methyl-glutaryl coenzyme. FOOD BIOSCIENCE, v. 44, n. B, DEC 2021. (13/07600-3, 14/50926-0)

MAZZEU, BRUNA F.; SOUZA-MOREIRA, TATIANA M.; OLIVEIRA, ANDREW A.; REMLINGER, MELISSA; FELIPPE, LIDIANE G.; VALENTINI, SANDRO R.; GUIDO, RAFAEL V. C.; ZANELLI, CLESLEI F.; FURLAN, MAYSA. The Methionine 549 and Leucine 552 Residues of Friedelin Synthase from Maytenus ilicifolia Are Important for Substrate Binding Specificity. Molecules, v. 26, n. 22, NOV 2021. (13/07600-3, 11/10379-1, 14/25705-0, 14/50926-0)

CHACON, DAISY SOTERO; TORRES, TAFFAREL MELO; DA SILVA, IVANICE BEZERRA; DE ARAUJO, THIAGO FERREIRA; ROQUE, ALAN DE ARAUJO; SENNA DOMINGOS PINHEIRO, FRANCISCO AYRTON; SELEGATO, DENISE; PILON, ALAN; SANTOS REGINALDO, FERNANDA PRISCILA; DA COSTA, CIBELE TESSER; et al. Erythrina velutina Willd. alkaloids: Piecing biosynthesis together from transcriptome analysis and metabolite profiling of seeds and leaves. JOURNAL OF ADVANCED RESEARCH, v. 34, n. SI, p. 123-136, DEC 2021. (14/50926-0)

CARNEIRO, ARIADNE MAGALHAES; MOREIRA, EDUARDA ANTUNES; BRAGAGNOLO, FELIPE SANCHEZ; BORGES, MAIARA STEFANINI; PILON, ALAN CESAR; RINALDO, DANIEL; FUNARI, CRISTIANO SOLEO. Soya agricultural waste as a rich source of isoflavones. Food Research International, v. 130, APR 2020. (16/13292-8, 14/50926-0, 16/08179-8, 17/06216-6)

DE FREITAS, LARISSA; VALLI, MARILIA; DAMETTO, ALESSANDRA C.; PENNACCHI, PAULA C.; ANDRICOPULO, ADRIANO D.; MARIA-ENGLER, SILVYA S.; BOLZANI, VANDERLAN S.. Advanced Glycation End Product Inhibition by Alkaloids from Ocotea paranapiacabensis for the Prevention of Skin Aging. Journal of Natural Products, v. 83, n. 3, SI, p. 649-656, MAR 27 2020. (14/50926-0, 19/05967-3, 13/07600-3)

RUSSO, HELENA MANNOCHIO; QUEIROZ, EMERSON FERREIRA; MARCOURT, LAURENCE; RUTZ, ADRIANO; ALLARD, PIERRE -MARIE; ALMEIDA, RAFAEL FELIPE DE; CARVALHO, NILTON MARQUES; WOLFENDER, JEAN-LUC; BOLZANI, VANDERLAN DA SILVA. Phytochemical analysis of the methanolic leaves extract of Niedenzuella multiglandulosa (Malpighiaceae), a plant species toxic to cattle in Brazil. PHYTOCHEMISTRY LETTERS, v. 37, p. 10-16, JUN 2020. (16/16970-7, 14/50926-0)

DOS SANTOS, GUSTAVO SOUZA; TEIXEIRA, THAIZ RODRIGUES; COLEPICOLO, PIO; DEBONSI, HOSANA MARIA. Natural Products from the Poles: Structural Diversity and Biological Activities. REVISTA BRASILEIRA DE FARMACOGNOSIA-BRAZILIAN JOURNAL OF PHARMACOGNOSY, v. 31, n. 5, p. 531-560, OCT 2021. (14/50926-0)

PRINCIPE, SILAS C.; ACOSTA, ANDRE L.; ANDRADE, JOAO E.; LOTUFO, TITO M. C.. Predicted Shifts in the Distributions of Atlantic Reef-Building Corals in the Face of Climate Change. FRONTIERS IN MARINE SCIENCE, v. 8, JUL 19 2021. (17/11948-6, 14/50926-0, 15/17177-6)

NUNES, WILHAN DONIZETE GONCALVES; RUSSO, HELENA MANNOCHIO; BOLZANI, VANDERLAN DA SILVA; CAIRES, FLAVIO JUNIOR. Thermal characterization and compounds identification of commercialStevia rebaudianaBertoni sweeteners and thermal degradation products at high temperatures by TG-DSC, IR and LC-MS/MS. JOURNAL OF THERMAL ANALYSIS AND CALORIMETRY, v. 146, n. 3, p. 1149-1155, NOV 2021. (13/07600-3, 18/24378-6, 16/16970-7, 14/50926-0)

ZAZERI, GABRIEL; RIBEIRO POVINELLI, ANA PAULA; PAVAN, NATHALIA M.; DE CARVALHO, DANIELLA ROMANO; CARDOSO, CARMEN LUCIA; XIMENES, VALDECIR FARIAS. Experimental studies and computational modeling on cytochrome c reduction by quercetin: The role of oxidability and binding affinity. Journal of Molecular Structure, v. 1244, NOV 15 2021. (14/50926-0, 19/18445-5)

RIBEIRO, DAYANE C.; RUSSO, HELENA M.; FRAIGE, KARINA; ZERAIK, MARIA L.; NOGUEIRA, CLAUDIO R.; DA SILVA, PATRICIA B.; CODO, ANA C.; CALIXTO, GIOVANA M. F.; DE MEDEIROS, ALEXANDRA I.; CHORILLI, MARLUS; et al. Bioactive Biofllavonoids from Platonia insignis (Bacuri) Residues as Added Value Compounds. Journal of the Brazilian Chemical Society, v. 32, n. 4, p. 786-799, APR 2021. (16/16970-7, 17/18807-9, 14/50926-0, 17/19870-6, 13/07600-3)

AMBROSE, ANDREW J.; PHAM, NHAN T.; SIVINSKI, JARED; GUIMARAES, LARISSA; MOLLASALEHI, NILOUFAR; JIMENEZ, PAULA; ABAD, MARIA A.; JEYAPRAKASH, A. AROCKIA; SHAVE, STEVEN; COSTA-LOTUFO, LETICIA V.; et al. A two-step resin based approach to reveal survivin-selective fluorescent probes. RSC CHEMICAL BIOLOGY, v. 2, n. 1, p. 181-186, FEB 1 2021. (14/50926-0, 15/17177-6)

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