INCT 2014: biodiversidade e produtos naturais

• Processo: 14/50926-0
• Modalidade de apoio: Auxílio à Pesquisa - Programa BIOTA - Temático
• Data de Início da vigência: 01 de julho de 2017
• Data de Término da vigência: 30 de abril de 2025
• Área do conhecimento: Ciências Exatas e da Terra - Química
• Acordo de Cooperação: CNPq - INCTs
• Pesquisador responsável: Vanderlan da Silva Bolzani
• Beneficiário: Vanderlan da Silva Bolzani
• Instituição Sede: Instituto de Química (IQ). Universidade Estadual Paulista (UNESP). Campus de Araraquara. Araraquara , SP, Brasil
• Pesquisadores principais:( Últimos ): Ian Castro-Gamboa ; Leticia Veras Costa Lotufo
• Pesquisadores principais:( Antigos ): Alberto Jose Cavalheiro ; Maria José Soares Mendes Giannini
• Auxílio(s) vinculado(s): 23/09497-7 - American Society of Pharmacognosy 2023 Annual Meeting, AR.EXT; 18/50025-3 - Green analytical chemistry applied to the investigation of agro industrial wastes generated in Brazil and Australia, AP.R SPRINT
• Bolsa(s) vinculada(s): 24/02602-2 - Metabolômica, uma metodologia de vanguarda para a identificação micromolecular e estudos de quimiossistemática em Bignoniaceae, BP.DR; 24/05515-3 - Perspectivas químicas e biológicas para o isolamento, caracterização e síntese de ciclopeptídeos de plantas, BP.PD; 23/00454-3 - Avaliação de novos inibidores duais de histona desacetilases e metaloproteinases em linhagens celulares de glioblastoma, BP.IC; 23/02775-1 - Prospecção de novas substâncias com potencial anticâncer em bactérias isoladas da ascídia Trididemnum maragogi, BP.IC
• Assunto(s): Biodiversidade Produtos naturais Metabólitos secundários Pesquisa básica Desenvolvimento de produtos Sustentabilidade Micro-organismos
• Palavra(s)-Chave do Pesquisador: Quimica
• Publicação FAPESP: https://media.fapesp.br/bv/uploads/pdfs/Brazilian_biodiversity...future_syWaC2Z_55_56.pdf

Resumo

O projeto delineado está centrado nos pilares de sustentação da Ciência, Tecnologia e Inovação, que norteiam as sociedades do conhecimento: (a) pesquisa básica e aplicada de excelência; (b) formação de recursos humanos em biodiversidade e produtos naturais; (c) colaboração com o setor empresarial para desenvolvimento tecnológico a partir das inovações em produtos naturais; (d) difusão do conhecimento sobre a biodiversidade e produtos naturais bioativos para o ensino médio e outros segmentos da sociedade; (e) contribuição nas ações de políticas públicas de conservação e uso sustentável da biodiversidade. Dentro destes fundamentos, o Instituto Nacional de Ciência & Tecnologia (INCTBioNat) foi criado para mapear e catalogar de forma organizada todas as informações sobre os metabólitos secundários detectados e/ou isolados de organismos de nossa rica biodiversidade, fundamental para o avanço de pesquisa em química de produtos naturais do Brasil. O conhecimento e uso sustentável da biodiversidade brasileira foi preconizado no documento Política Nacional da Biodiversidade, editado pela Secretaria de Biodiversidade e Florestas (SBF), Ministério do Meio Ambiente (MMA), em 2002 e tem prioridade para o desenvolvimento nacional. A criação de uma rede nacional de pesquisa para mapeamento químico e biológico das espécies terrestres, marinhas e de microrganismos da nossa biodiversidade constitui-se numa estratégia racional para a seleção de substâncias ativas mais promissoras para posterior estudos farmacológicos e toxicológicos visando moléculas protótipos. Para atingir tais metas, o ICNTBioNat reúne pesquisadores de excelência e pesquisadores jovens e talentosos que iniciam suas carreiras em universidades federais e estaduais de vários estados da federação, englobando todas as regiões do Brasil. Toda equipe atuará de forma colaborativa e multidisciplinar objetivando o fortalecimento de uma área de pesquisa e inovação estratégica para o Brasil, através de uma rede de laboratórios de excelência em produtos naturais para exploração e uso sustentável da rica biodiversidade brasileira. (AU)

Publicações científicas

(160)

(Referências obtidas automaticamente do Web of Science e do SciELO, por meio da informação sobre o financiamento pela FAPESP e o número do processo correspondente, incluída na publicação pelos autores)

MAIARA S. BORGES; CAROLINA R. BIASETTO; VANESSA M. CHAPLA; SAMAD N. EBRAHIMI; MAYRA F. COSTA; VANDERLAN S. BOLZANI; ANGELA R. ARAUJO. Assessment of Novel C-4 Methylated Tetraketide by HPLC-SPE-TT in Saccharicola sp., an Endophytic Fungus in Eugenia jambolana Lam.. Journal of the Brazilian Chemical Society, v. 30, n. 3, p. 522-527, 2019-03-00. (14/50926-0, 13/07600-3)

DANIELE RODRIGUES DE LIMA; MARIA GLEIZIANE DE ARAÚJO FRANCA; FÁTIMA DE CÁSSIA EVANGELISTA DE OLIVEIRA; CLÁUDIA DO Ó PESSOA; ALBERTO JOSÉ CAVALHEIRO; MARIA GORETTI DE VASCONCELOS SILVA. METABOLIC PROFILING AND CYTOTOXIC ACTIVITY OF METHANOL EXTRACTS FROM CHAMAECRISTA DUCKEANA (P. BEZERRA & A. FERN.) H. S. IRWIN & BARNEBY (LEGUMINOSAE, CAESALPINIOIDEAE). Química Nova, v. 45, n. 7, p. 803-806, 2022-09-26. (13/07600-3, 14/50926-0)

BERTOZO, LUIZA DE CARVALHO; NETO, ERNESTO TAVARES; DE OLIVEIRA, LEANDRO CRISTANTE; XIMENES, VALDECIR FARIAS. Oxidative Alteration of Trp-214 and Lys-199 in Human Serum Albumin Increases Binding Affinity with Phenylbutazone: A Combined Experimental and Computational Investigation. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, v. 19, n. 10, OCT 2018. (14/50926-0, 16/20549-5, 16/22014-1)

FERREIRA SANTOS, NATACHA CARVALHO; VALLI, MARILIA; BOLZANI, VANDERLAN DA SILVA. A brief overview on Brazilian women in chemistry. Pure and Applied Chemistry, v. 91, n. 4, SI, p. 743-749, APR 2019. (14/50926-0, 13/07600-3)

NUNES, WILHAN DONIZETE GONCALVES; RUSSO, HELENA MANNOCHIO; BOLZANI, VANDERLAN DA SILVA; CAIRES, FLAVIO JUNIOR. Thermal characterization and compounds identification of commercialStevia rebaudianaBertoni sweeteners and thermal degradation products at high temperatures by TG-DSC, IR and LC-MS/MS. JOURNAL OF THERMAL ANALYSIS AND CALORIMETRY, AUG 2020. (18/24378-6, 14/50926-0, 13/07600-3, 16/16970-7)

DE FREITAS, LARISSA; VALLI, MARILIA; DAMETTO, ALESSANDRA C.; PENNACCHI, PAULA C.; ANDRICOPULO, ADRIANO D.; MARIA-ENGLER, SILVYA S.; BOLZANI, VANDERLAN S.. Advanced Glycation End Product Inhibition by Alkaloids from Ocotea paranapiacabensis for the Prevention of Skin Aging. Journal of Natural Products, v. 83, n. 3, SI, p. 649-656, MAR 27 2020. (14/50926-0, 19/05967-3, 13/07600-3)

DANUELLO, AMANDA; DE CASTRO, ROGERIO CARDOSO; PILON, ALAN CESAR; PIRES BUENO, PAULA CAROLINA; PIVATTO, MARCOS; VIEIRA JUNIOR, GERARDO MAGELA; CARVALHO, FLAVIO ALEXANDRE; ODA, FERNANDO BOMBARDA; PEREZ, CONSUELO JAVIERA; LOPES, NORBERTO PEPORINE; et al. Fragmentation study of clerodane diterpenes from Casearia species by tandem mass spectrometry (quadrupole time-of-flight and ion trap). RAPID COMMUNICATIONS IN MASS SPECTROMETRY, v. 34, n. 3, SI, MAY 2020. (11/21440-3, 16/13292-8, 17/19702-6, 13/07600-3, 14/50926-0)

WOLF, VANESSA GONCALVES; BONACORSI, CIBELE; GONCALVES RADDI, MARIA STELLA; DA FONSECA, LUIZ MARCOS; XIMENES, VALDECIR FARIAS. Octyl gallate, a food additive with potential beneficial properties to treat Helicobacter pylori infection. FOOD & FUNCTION, v. 8, n. 7, p. 2500-2511, JUL 1 2017. (14/50926-0, 15/21693-0)

SALDIVAR-GONZALEZ, FERNANDA I.; VALLI, MARILIA; ANDRICOPULO, ADRIANO D.; BOLZANI, VANDERLAN DA SILVA; MEDINA-FRANCO, JOSE L.. Chemical Space and Diversity of the NuBBE Database: A Chemoinformatic Characterization. JOURNAL OF CHEMICAL INFORMATION AND MODELING, v. 59, n. 1, p. 74-85, JAN 2019. (14/50926-0, 13/07600-3)

XIMENES, VALDECIR FARIAS; MORGON, NELSON HENRIQUE; DE SOUZA, AGUINALDO ROBINSON. Solvent-dependent inversion of circular dichroism signal in naproxen: An unusual effect!. CHIRALITY, v. 30, n. 9, p. 1049-1053, SEP 2018. (14/50926-0, 15/22338-9, 16/20549-5)

SOUSA, IRAN DA L.; HEERDT, GABRIEL; XIMENES, VALDECIR F.; DE SOUZA, AGUINALDO R.; MORGON, NELSON H.. TD-DFT Analysis of the Dissymmetry Factor in Camphor. Journal of the Brazilian Chemical Society, v. 31, n. 3, p. 613-618, MAR 2020. (14/50926-0, 16/20549-5, 15/22338-9, 16/04963-6, 19/12294-5)

DE VASCONCELOS, DEBORA NALIATI; LIMA, ANGELICA NAKAGAWA; PHILOT, ERIC ALLISON; SCOTT, ANA LIGIA; FERREIRA BOZA, IZABELLE AMORIM; DE SOUZA, AGUINALDO ROBINSON; MORGON, NELSON HENRIQUE; XIMENES, VALDECIR FARIAS. Methyl divanillate: redox properties and binding affinity with albumin of an antioxidant and potential NADPH oxidase inhibitor. RSC ADVANCES, v. 9, n. 35, p. 19983-19992, JUL 1 2019. (14/50926-0, 16/20549-5, 16/22014-1)

FUNARI, CRISTIANO SOLEO; CAVALHEIRO, ALBERTO JOSE; CARNEIRO, RENATO LAJARIM. Coupled monolithic columns as an alternative for the use of viscous ethanol-water mobile phases on chromatographic fingerprinting complex samples. REVISTA BRASILEIRA DE FARMACOGNOSIA-BRAZILIAN JOURNAL OF PHARMACOGNOSY, v. 28, n. 3, p. 261-266, MAY-JUN 2018. (14/50926-0, 13/07600-3, 10/18840-7)

MARQUES, BEATRIZ C.; SANTOS, MARIANA B.; ANSELMO, DAIANE B.; MONTEIRO, DIEGO A.; GOMES, ELENI; SAIKI, MARILIA F. C.; RAHAL, PAULA; ROSALEN, PEDRO L.; SARDI, JANAINA C. O.; REGASINI, LUIS O.. Methoxychalcones: Effect of Methoxyl Group on the Antifungal Antibacterial and Antiproliferative Activities. Medicinal Chemistry, v. 16, n. 7, p. 881-891, 2020. (14/18330-0, 17/09245-7, 14/18577-5, 09/53989-4, 18/15083-2, 16/08084-7, 14/50926-0)

CARNEIRO, ARIADNE MAGALHAES; MOREIRA, EDUARDA ANTUNES; BRAGAGNOLO, FELIPE SANCHEZ; BORGES, MAIARA STEFANINI; PILON, ALAN CESAR; RINALDO, DANIEL; FUNARI, CRISTIANO SOLEO. Soya agricultural waste as a rich source of isoflavones. Food Research International, v. 130, APR 2020. (16/13292-8, 14/50926-0, 16/08179-8, 17/06216-6)

PRINCIPE, SILAS C.; ACOSTA, ANDRE L.; ANDRADE, JOAO E.; LOTUFO, TITO M. C.. Predicted Shifts in the Distributions of Atlantic Reef-Building Corals in the Face of Climate Change. FRONTIERS IN MARINE SCIENCE, v. 8, JUL 19 2021. (17/11948-6, 14/50926-0, 15/17177-6)

RIBEIRO, SABRINA M.; FRATUCELLI, ERICK D. O.; BUENO, PAULA C. P.; DE CASTRO, V, MARLENE KELLY; FRANCISCO, AMANDA ALCALA; CAVALHEIRO, ALBERTO JOSE; KLEIN, I, MARLISE. Antimicrobial and antibiofilm activities of Casearia sylvestris extracts from distinct Brazilian biomes against Streptococcus mutans and Candida albicans. BMC COMPLEMENTARY AND ALTERNATIVE MEDICINE, v. 19, n. 1, NOV 12 2019. (13/07600-3, 14/50926-0, 11/21440-3, 12/21921-4, 17/07408-6)

BIASETTO, CAROLINA R.; SOMENSI, ANDRESSA; SORDI, RENATA; CHAPLA, VANESSA M.; EBRAHIMI, SAMAD N.; SILVA, GERALDO H.; TELES, HELDER L.; BOLZANI, VANDERLAN DA S.; YOUNG, MARIA CLAUDIA M.; PFENNING, LUDWIG H.; et al. The new koninginins T-U from Phomopsis stipata, an endophytic fungus isolated from Styrax camporum Pohl. PHYTOCHEMISTRY LETTERS, v. 36, p. 106-110, APR 2020. (14/50926-0, 13/07600-3, 03/02176-7)

FERNANDEZ-BOBEY, ANTONIO; FERREIRA PINTO, MERI EMILI; DE ALMEIDA, LARISSA COSTA; DE SOUZA, BIBIANA MONSON; DIAS, NATHALIA BAPTISTA; DE PAULA-SOUZA, JULIANA; CILLI, EDUARDO MAFFUD; LOPES, NORBERTO PEPORINE; COSTA-LOTUFO, LETICIA VERAS; PALMA, MARIO SERGIO; et al. Cytotoxic Cyclotides from Anchietea pyrifolia, a South American Plant Species. Journal of Natural Products, v. 85, n. 9, p. 8-pg., 2022-08-31. (14/50926-0, 19/04381-5, 20/02207-5, 14/25222-9, 13/07600-3, 19/26550-3, 17/17098-4, 16/16212-5)

SANCHEZ BRAGAGNOLO, FELIPE; SOCAS-RODRIGUEZ, BARBARA; MENDIOLA, JOSE A.; CIFUENTES, ALEJANDRO; SOLEO FUNARI, CRISTIANO; IBANEZ, ELENA. Pressurized natural deep eutectic solvents: An alternative approach to agro-soy by-products. FRONTIERS IN NUTRITION, v. 9, p. 14-pg., 2022-09-08. (14/50926-0, 20/09500-0, 18/21128-9, 17/06216-6, 18/01786-1)

BICALHO, KEYLLA U.; SANTONI, MARIANA M.; ARENDT, PHILIPP; ZANELLI, CLESLEI F.; FURLAN, MAYSA; GOOSSENS, ALAIN; POLLIER, JACOB. CYP712K4 Catalyzes the C-29 Oxidation of Friedelin in the Maytenus ilicifolia Quinone Methide Triterpenoid Biosynthesis Pathway. Plant and Cell Physiology, v. 60, n. 11, p. 2510-2522, NOV 2019. (14/50926-0, 13/07600-3, 15/25175-3, 17/10911-1, 16/16970-7)

DE ALMEIDA, LARISSA COSTA; BAUERMEISTER, ANELIZE; REZENDE-TEIXEIRA, PAULA; DOS SANTOS, EVELYNE ALVES; BERALDO DE MORAES, LUIZ ALBERTO; MACHADO-NETO, JOAO AGOSTINHO; COSTA-LOTUFO, LETICIA VERAS. Pradimicin-IRD exhibits antineoplastic effects by inducing DNA damage in colon cancer cells. Biochemical Pharmacology, v. 168, p. 38-47, OCT 2019. (17/17648-4, 15/17177-6, 18/17595-0, 17/24993-0, 14/50926-0)

SELEGATO, DENISE M.; FREITAS, THAMIRES R.; PIVATTO, MARCOS; PIVATTO, AMANDA D.; PILON, ALAN C.; CASTRO-GAMBOA, IAN. Time-related multivariate strategy for the comprehensive evaluation of microbial chemical data. METABOLOMICS, v. 18, n. 6, p. 14-pg., 2022-05-24. (14/05935-0, 13/07600-3, 14/50926-0)

SOUZA, OTAVIO AGUIAR; RAMALHAO, VICTORIA GIOVANNA DA SILVA; TRENTIN, LUCAS DE MELO; FUNARI, CRISTIANO SOLEO; CARNEIRO, RENATO LAJARIM; BOLZANI, VANDERLAN DA SILVA; RINALDO, DANIEL. Combining natural deep eutectic solvent and microwave irradiation towards the eco-friendly and optimized extraction of bioactive phenolics from Eugenia uniflora L.. SUSTAINABLE CHEMISTRY AND PHARMACY, v. 26, p. 16-pg., 2022-05-01. (18/01786-1, 14/50926-0, 16/08179-8)

RIBEIRO, DAYANE C.; RUSSO, HELENA M.; FRAIGE, KARINA; ZERAIK, MARIA L.; NOGUEIRA, CLAUDIO R.; DA SILVA, PATRICIA B.; CODO, ANA C.; CALIXTO, GIOVANA M. F.; DE MEDEIROS, ALEXANDRA I.; CHORILLI, MARLUS; et al. Bioactive Biofllavonoids from Platonia insignis (Bacuri) Residues as Added Value Compounds. Journal of the Brazilian Chemical Society, v. 32, n. 4, p. 786-799, APR 2021. (16/16970-7, 17/18807-9, 14/50926-0, 17/19870-6, 13/07600-3)

VALLI, MARILIA; ATANAZIO, LETICIA CRISTINA VIEIRA; MONTEIRO, GUSTAVO CLARO; COELHO, ROBERTA RAMOS; DEMARQUE, DANIEL PECORARO; ANDRICOPULO, ADRIANO DEFINI; ESPINDOLA, LAILA SALMEN; BOLZANI, VANDERLAN DA SILVA. The Potential of Biologically Active Brazilian Plant Species as a Strategy to Search for Molecular Models for Mosquito Control. Planta Medica, v. 87, n. 01/02, p. 6-23, FEB 2021. (14/50926-0, 13/07600-3, 19/05967-3)

SANTOS REGINALDO, FERNANDA PRISCILA; PIRES BUENO, PAULA CAROLINA; DE MATOS COSTA, ISABELLY CRISTINA; ROQUE, ALAN DE ARAUJO; FETT-NETO, ARTHUR GERMANO; CAVALHEIRO, ALBERTO JOSE; GIORDANI, RAQUEL BRANDT. Molecular Networking Discloses the Chemical Diversity of Flavonoids and Selaginellins in Selaginella convoluta. Planta Medica, v. 87, n. 01/02, p. 113-123, FEB 2021. (14/50926-0, 19/08477-7, 17/19702-6)

TORREZAN, GUILHERME SILVA; POLAQUINI, CARLOS ROBERTO; LIMA, MARCELO FREITAS; REGASINI, LUIS OCTAVIO. Use of glycerol, waste glycerol from biodiesel production and other protic solvents in bioactive alpha, beta-unsaturated ketones synthesis. SUSTAINABLE CHEMISTRY AND PHARMACY, v. 16, JUN 2020. (18/15083-2, 09/53989-4, 14/50926-0, 14/18330-0)

GRATON, MURILO E.; FERREIRA, BRUNO H. S. H.; TROIANO, JESSICA A.; POTJE, SIMONE. R. R.; VALE, GABRIEL. T. T.; NAKAMUNE, ANA CLAUDIA M. S.; TIRAPELLI, CARLOS R.; MILLER, FRANCIS. J. J.; XIMENES, VALDECIR. F. F.; ANTONIALI, CRISTINA. Comparative study between apocynin and protocatechuic acid regarding antioxidant capacity and vascular effects. FRONTIERS IN PHYSIOLOGY, v. 13, p. 14-pg., 2022-11-15. (16/22180-9, 16/01476-7, 17/18436-0, 14/50926-0)

REGINALDO, FERNANDA PRISCILA SANTOS; BUENO, PAULA CAROLINA PIRES; LOURENCO, ESTELA MARIANA GUIMARAES; DE MATOS COSTA, ISABELLY CRISTINA; MOREIRA, LETICIA GONDIM LAMBERT; DE ARAUJO ROQUE, ALAN; BARBOSA, EUZEBIO GUIMARAES; FETT-NETO, ARTHUR GERMANO; CAVALHEIRO, ALBERTO JOSE; GIORDANI, RAQUEL BRANDT. Methyl jasmonate induces selaginellin accumulation in Selaginella convoluta. METABOLOMICS, v. 19, n. 1, p. 13-pg., 2022-12-21. (14/50926-0, 19/08477-7, 17/19702-6)

AMBROSE, ANDREW J.; PHAM, NHAN T.; SIVINSKI, JARED; GUIMARAES, LARISSA; MOLLASALEHI, NILOUFAR; JIMENEZ, PAULA; ABAD, MARIA A.; JEYAPRAKASH, A. AROCKIA; SHAVE, STEVEN; COSTA-LOTUFO, LETICIA V.; et al. A two-step resin based approach to reveal survivin-selective fluorescent probes. RSC CHEMICAL BIOLOGY, v. 2, n. 1, p. 181-186, FEB 1 2021. (14/50926-0, 15/17177-6)

NUNES, WILHAN DONIZETE GONCALVES; RUSSO, HELENA MANNOCHIO; BOLZANI, VANDERLAN DA SILVA; CAIRES, FLAVIO JUNIOR. Thermal characterization and compounds identification of commercialStevia rebaudianaBertoni sweeteners and thermal degradation products at high temperatures by TG-DSC, IR and LC-MS/MS. JOURNAL OF THERMAL ANALYSIS AND CALORIMETRY, v. 146, n. 3, p. 1149-1155, NOV 2021. (13/07600-3, 18/24378-6, 16/16970-7, 14/50926-0)

ZAZERI, GABRIEL; RIBEIRO POVINELLI, ANA PAULA; PAVAN, NATHALIA M.; DE CARVALHO, DANIELLA ROMANO; CARDOSO, CARMEN LUCIA; XIMENES, VALDECIR FARIAS. Experimental studies and computational modeling on cytochrome c reduction by quercetin: The role of oxidability and binding affinity. Journal of Molecular Structure, v. 1244, NOV 15 2021. (14/50926-0, 19/18445-5)

ZERAIK, MARIA LUIZA; PAULI, IVANI; DUTRA, LUIZ A.; CRUZ, RAQUEL S.; VALLI, MARILIA; PARACATU, LUANA C.; DE FARIA, CAROLINA M. Q. G.; XIMENES, VALDECIR F.; REGASINI, LUIS O.; ANDRICOPULO, ADRIANO D.; et al. Identification of a Prenyl Chalcone as a Competitive Lipoxygenase Inhibitor: Screening, Biochemical Evaluation and Molecular Modeling Studies. Molecules, v. 26, n. 8, APR 2021. (10/01506-7, 13/07600-3, 11/03017-6, 19/05967-3, 19/18445-5, 09/15457-0, 14/50926-0)

CASTANEDA, CAROL; BRAVO, KARENT; CORTES, NATALIE; BEDOYA, JANETH; BORGES, WARLEY DE S.; BASTIDA, JAUME; OSORIO, EDISON. Amaryllidaceae alkaloids in skin cancer management: Photoprotective effect on human keratinocytes and anti-proliferative activity in melanoma cells. JOURNAL OF APPLIED BIOMEDICINE, v. 21, n. 1, p. 12-pg., 2023-03-31. (14/50926-0)

RUSSO, HELENA MANNOCHIO; QUEIROZ, EMERSON FERREIRA; MARCOURT, LAURENCE; RUTZ, ADRIANO; ALLARD, PIERRE -MARIE; ALMEIDA, RAFAEL FELIPE DE; CARVALHO, NILTON MARQUES; WOLFENDER, JEAN-LUC; BOLZANI, VANDERLAN DA SILVA. Phytochemical analysis of the methanolic leaves extract of Niedenzuella multiglandulosa (Malpighiaceae), a plant species toxic to cattle in Brazil. PHYTOCHEMISTRY LETTERS, v. 37, p. 10-16, JUN 2020. (16/16970-7, 14/50926-0)

DOS SANTOS, MARIANA BASTOS; MARQUES, BEATRIZ CARVALHO; AYUSSO, GABRIELA MIRANDA; ROCHA GARCIA, MAYARA APARECIDA; PARACATU, LUANA CHIQUETTO; PAULI, IVANI; BOLZANI, VANDERLAN SILVA; ANDRICOPULO, ADRIANO DEFINI; XIMENES, VALDECIR FARIAS; ZERAIK, MARIA LUIZA; et al. Chalcones and their B-aryl analogues as myeloperoxidase inhibitors: In silico, in vitro and ex vivo investigations. BIOORGANIC CHEMISTRY, v. 110, MAY 2021. (16/00580-5, 14/18330-0, 09/53989-4, 18/15083-2, 14/50926-0)

SANCHEZ BRAGAGNOLO, FELIPE; ALVAREZ-RIVERA, GERARDO; BREITKREITZ, MARCIA CRISTINA; IBANEZ, ELENA; CIFUENTES, ALEJANDRO; FUNARI, CRISTIANO SOLEO. Metabolite Profiling of Soy By-Products: A Comprehensive Approach. Journal of Agricultural and Food Chemistry, v. 70, n. 23, p. 21-pg., 2022-06-15. (18/21128-9, 14/50926-0, 17/06216-6, 18/01786-1, 20/09500-0)

CHACON, DAISY SOTERO; TORRES, TAFFAREL MELO; DA SILVA, IVANICE BEZERRA; DE ARAUJO, THIAGO FERREIRA; ROQUE, ALAN DE ARAUJO; SENNA DOMINGOS PINHEIRO, FRANCISCO AYRTON; SELEGATO, DENISE; PILON, ALAN; SANTOS REGINALDO, FERNANDA PRISCILA; DA COSTA, CIBELE TESSER; et al. Erythrina velutina Willd. alkaloids: Piecing biosynthesis together from transcriptome analysis and metabolite profiling of seeds and leaves. JOURNAL OF ADVANCED RESEARCH, v. 34, n. SI, p. 123-136, DEC 2021. (14/50926-0)

BITENCOURT, NATALIA VITORIA; RIGHETTO, GABRIELA MARINHO; CAMARGO, ILANA LOPES BARATELLA CUNHA; DE GODOY, MARIANA ORTIZ; GUIDO, RAFAEL VICTORIO CARVALHO; OLIVA, GLAUCIUS; SANTOS-FILHO, NORIVAL ALVES; CILLI, EDUARDO MAFFUD. Effects of Dimerization, Dendrimerization, and Chirality in p-BthTX-I Peptide Analogs on the Antibacterial Activity and Enzymatic Inhibition of the SARS-CoV-2 PLpro Protein. PHARMACEUTICS, v. 15, n. 2, p. 17-pg., 2023-02-01. (13/07600-3, 14/50926-0, 20/12904-5)

BARBOSA, MARILIA FONTES; PIVATTO, MARCOS; CARDOSO, ARNALDO ALVES; PETRUCI, JOAO FLAVIO DA SILVEIRA. Analysis of cassine and spectaline in the Senna spectabilis ethanolic extracts by capillary zone electrophoresis with indirect UV detection. Phytochemical Analysis, v. 35, n. 7, p. 7-pg., 2024-06-24. (14/50926-0)

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ZANATTA, ANA C.; BORGES, MAIARA S.; MANNOCHIO-RUSSO, HELENA; HEREDIA-VIEIRA, SILVIA CRISTINA; DOS SANTOS, LOURDES CAMPANER; RINALDO, DANIEL; VILEGAS, WAGNER. Green chromatography as a novel alternative for the quality control of Serjania marginata Casar. Leaves. Microchemical Journal, v. 181, p. 12-pg., 2022-06-15. (14/50926-0, 16/21044-4, 16/08179-8, 19/18673-8)

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SANTOS, VANIA A. F. M.; DIAS, NATHALIA B.; TEIXEIRA, SIMONE P.; PALMA, MARIO S.; FURLAN, MAYSA. Mapping Biochemical Pathways in Maytenus ilicifolia (Celastraceae) through Integrated Proteomics and Histochemistry. Journal of the Brazilian Chemical Society, v. 32, n. 2, p. 12-pg., 2021-02-01. (14/50926-0, 13/07600-3)

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DA SILVA, WALACE BRENO; HISPAGNOL, GABRIEL FELIPE; NUNES, EMANUEL VICTOR DOS SANTOS; CASTRO-GAMBOA, IAN; PILON, ALAN CESAR. Plant Sample Preparation for Metabolomics, Lipidomics, Ionomics, Fluxomics, and Peptidomics. SEPARATIONS, v. 12, n. 2, p. 21-pg., 2025-02-01. (19/15889-0, 20/02207-5, 14/50926-0, 20/11967-3)

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SCUPINARI, TAMIRES; MANNOCHIO-RUSSO, HELENA; MARCHEAFAVE, GUSTAVO GALO; DA SILVA BOLZANI, VANDERLAN; DE OLIVEIRA NUNES, ESTELA; DIAS, WALDIR PEREIRA; HOFFMANN-CAMPO, CLARA BEATRIZ; ZERAIK, MARIA LUIZA. Effects of Crotalaria spectabilis extract in Meloidogyne javanica and Heterodera glycines soybean nematodes. European Journal of Plant Pathology, v. N/A, p. 12-pg., 2024-01-24. (14/50926-0, 13/07600-3)