INCT 2014: Translacional em Medicina

• Processo: 14/50891-1
• Modalidade de apoio: Auxílio à Pesquisa - Temático
• Data de Início da vigência: 01 de julho de 2017
• Data de Término da vigência: 28 de fevereiro de 2025
• Área do conhecimento: Ciências da Saúde - Medicina
• Acordo de Cooperação: CNPq - INCTs
• Pesquisador responsável: Jaime Eduardo Cecilio Hallak
• Beneficiário: Jaime Eduardo Cecilio Hallak
• Instituição Sede: Faculdade de Medicina de Ribeirão Preto (FMRP). Universidade de São Paulo (USP). Ribeirão Preto , SP, Brasil
• Pesquisadores principais:( Últimos ): Acioly Luiz Tavares de Lacerda ; Antonio Lucio Teixeira Junior ; Antonio Waldo Zuardi ; Danielle Macedo Gaspar ; Flavio Pereira Kapczinski ; João Paulo Maia de Oliveira ; José Alexandre de Souza Crippa ; Maria Eugênia Queiroz Nassur ; Nadja Schroder ; Ricardo Machado Xavier ; Vanessa Costhek Abílio
• Pesquisadores principais:( Antigos ): Mirian Akemi Furuie Hayashi
• Bolsa(s) vinculada(s): 22/00211-0 - Mecanismos de ação do nitroprussiato de sódio como estratégia terapêutica preventiva para a Esquizofrenia, BP.DR; 19/22120-4 - Tratamento sistêmico com canabidiol em ratos das linhagens cariocas de alto e baixo congelamento no modelo de dor crônica: avaliação da sensibilidade dolorosa, do componente afetivo da dor, da ansiedade e sua expressão de BDNF, BP.DR; 19/09207-3 - Estudo do(s) mecanismo(s) molecular(es) e celular(es) em transtornos mentais, BP.DR; 19/02787-4 - Efeitos do canabidiol veiculado em nanoemulsão em ratos submetidos ao modelo químico de epilepsia do lobo temporal, BP.IC; 18/06877-5 - Tratamento sistêmico com canabidiol em modelo de dor neuropática: avaliação dos componentes sensorial-discriminativo e emocional-motivacional da sensibilidade dolorosa, BP.DR
• Assunto(s): Pesquisa médica translacional Biomarcadores Transtornos neuropsicológicos Institutos de pesquisa
• Palavra(s)-Chave do Pesquisador: Medicina

Resumo

O Instituto Nacional de Ciência e Tecnologia Translacional em Medicina (INCT-TM) foi criado em 2008 com o propósito de estabelecer uma rede nacional de centros de pesquisa de destaque na investigação de biomarcadores e de novos alvos terapêuticos e moléculas capazes de atuar em transtornos neuropsiquiátricos, inserindo-se na área estratégica de Saúde e Fármacos definida pelo Governo Federal. Na base de todas as atividades do INCT-TM, a pesquisa translacional visa agilizar a aplicação de dados de pesquisa básica no contexto clínico e oferece possibilidades importantes para que o Brasil desenvolva seu potencial de geração de inovação a partir de sua produção acadêmica. Superando suas metas originais, o INCT-TM gerou mais de 600 publicações em periódicos internacionais e o depósito de nove pedidos de patente. Em termos qualitativos, o INCT- TM produziu achados importantes sobre o papel das neurotrofinas (particularmente o BONF, Brain-Oerived Neurotrophic Factor) e de novas drogas como o canabidiol (CBO) e o nitroprussiato de sódio (NP) no contexto dos transtornos neuropsiquiátricos. O instituto também teve importante atuação na formação e capacitação de recursos humanos, com o intercâmbio de pesquisadores entre centros nacionais e internacionais e a defesa de um grande número de teses e dissertações, além de promover a transferência de conhecimento científico para a comunidade e o setor produtivo e de favorecer a inserção de grupos nacionais no contexto internacional de pesquisa de ponta. Em sua proposta atual, com um grupo formado por cerca de 90 doutores distribuídos em 8 centros do sul, sudeste e nordeste do Brasil, o INCT-TM irá atuar em todas as áreas anteriores, com destaque para a pesquisa sobre moléculas promissoras para o tratamento de transtornos e sintomas neuropsiquiátricos (CBO, Np, ayahuasca, N-acetilcisteína, entre outros) visando o aumento da produtividade e representatividade da pesquisa brasileira através da produção de conhecimento e inovação com potencial de geração de dividendos para o país e as instituições envolvidas. (AU)

Publicações científicas

(54)

(Referências obtidas automaticamente do Web of Science e do SciELO, por meio da informação sobre o financiamento pela FAPESP e o número do processo correspondente, incluída na publicação pelos autores)

GOMEZ-NIETO, RICARDO; LOPEZ, DOLORES E.; GARCIA-CAIRASCO, NORBERTO. Editorial: Challenges and Conundrums in Cannabinoid-Based Treatments for Epilepsy Syndromes and Associated Neurobehavioral Comorbidities. FRONTIERS IN BEHAVIORAL NEUROSCIENCE, v. 15, p. 4-pg., 2021-11-11. (19/05957-8, 19/16574-2, 14/50891-1, 19/00849-2, 19/02787-4)

CORAL RAKOVSKI; TAIANE DE AZEVEDO CARDOSO; JUREMA CORRÊA DA MOTA; FRANCISCO I. BASTOS; FLAVIO KAPCZINSKI; RAQUEL BRANDINI DE BONI. Underage drinking in Brazil: findings from a community household survey. Revista Brasileira de Psiquiatria, v. 44, n. 3, p. 257-263, 2021-12-15. (14/50891-1)

MARIO SIMJANOSKI; PEDRO L. BALLESTER; JUREMA CORRÊA DA MOTA; RAQUEL B. DE BONI; VICENT BALANZÁ-MARTÍNEZ; BEATRIZ ATIENZA-CARBONELL; FRANCISCO I. BASTOS; BENICIO N. FREY; LUCIANO MINUZZI; TAIANE DE AZEVEDO CARDOSO; et al. Lifestyle predictors of depression and anxiety during COVID-19: a machine learning approach. Trends in Psychiatry and Psychotherapy, v. 44, 2022-05-30. (14/50891-1)

MAIA BEZERRA, NATHALIA KAREN; DE MENEZES GALVAO, ANA CECILIA; MARTINS LEITE, NATHALIA EVELYN; LEAO BARBALHO SANT'ANNA, ADRIANA; DE MEDEIROS GARCIA TORRES, MYCHELLE; GALVAO PINTO COELHO, MARIA CECILIA; KENJI MEDEIROS SHIRAMIZU, VICTOR; DE SOUSA, MARIA BERNARDETE CORDEIRO; LEITE GALVAO-COELHO, NICOLE. Success ofin vitrofertilization and its association with the levels of psychophysiological stress before and during the treatment. HEALTH CARE FOR WOMEN INTERNATIONAL, v. 42, n. 4-6, p. 420-445, JUL 1 2021. (14/50891-1)

GINER-MURILLO, MARIA; ATIENZA-CARBONELL, BEATRIZ; CERVERA-MARTINEZ, JOSE; BOBES-BASCARAN, TERESA; CRESPO-FACORRO, BENEDICTO; DE BONI, RAQUEL B.; ESTEBAN, CRISTINA; GARCIA-PORTILLA, MARIA PAZ; GOMES-DA-COSTA, SUSANA; GONZALEZ-PINTO, ANA; et al. Lifestyle in Undergraduate Students and Demographically Matched Controls during the COVID-19 Pandemic in Spain. INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH, v. 18, n. 15, AUG 2021. (14/50891-1)

LAZARINI-LOPES, WILLIAN; DO VAL-DA SILVA, RAQUEL A.; DA SILVA-JUNIOR, RUI M. P.; LEITE, JOAO P.; GARCIA-CAIRASCO, NORBERTO. The anticonvulsant effects of cannabidiol in experimental models of epileptic seizures: From behavior and mechanisms to clinical insights. NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS, v. 111, p. 166-182, APR 2020. (19/05957-8, 14/50891-1, 19/00849-2)

DAMASCENO, SAMARA; GOMEZ-NIETO, RICARDO; GARCIA-CAIRASCO, NORBERTO; JAVIER HERRERO-TURRION, MANUEL; MARIN, FAUSTINO; LOPEZ, DOLORES E.. Top Common Differentially Expressed Genes in the Epileptogenic Nucleus of Two Strains of Rodents Susceptible to Audiogenic Seizures: WAR and GASH/Sal. FRONTIERS IN NEUROLOGY, v. 11, FEB 13 2020. (14/50891-1)

DE MEDEIROS RAMALHO, IZOLA MORAIS; PEREIRA, DANIEL TORRES; LIMA GALVAO, GIOVANNA BRUNELLY; FREIRE, DANIELLE TEIXEIRA; AMARAL-MACHADO, LUCAS; ALENCAR, EVERTON DO NASCIMENTO; TABOSA DO EGITO, ERYVALDO SOCRATES. Current trends on cannabidiol delivery systems: where are we and where are we going?. Expert Opinion on Drug Delivery, v. 18, n. 11, JUL 2021. (14/50891-1)

GARCIA-CAIRASCO, NORBERTO; PODOLSKY-GONDIM, GUILHERME; TEJADA, JULIAN. Searching for a paradigm shift in the research on the epilepsies and associated neuropsychiatric comorbidities. From ancient historical knowledge to the challenge of contemporary systems complexity and emergent functions. Epilepsy & Behavior, v. 121, n. B, AUG 2021. (19/05957-8, 14/50891-1)

DE BONI, RAQUEL BRANDINI; BALANZA-MARTINEZ, VICENT; MOTA, JUREMA CORREA; CARDOSO, TAIANE DE AZEVEDO; BALLESTER, PEDRO; ATIENZA-CARBONELL, BEATRIZ; BASTOS, I, FRANCISCO; KAPCZINSKI, FLAVIO. Depression, Anxiety, and Lifestyle Among Essential Workers: A Web Survey From Brazil and Spain During the COVID-19 Pandemic. JOURNAL OF MEDICAL INTERNET RESEARCH, v. 22, n. 10, OCT 30 2020. (14/50891-1)

OSORIO, FLAVIA L.; ZUARDI, ANTONIO WALDO; SILVEIRA, ISABELLA L. M.; CRIPPA, JOSE ALEXANDRE S.; HALLAK, JAIME EDUARDO CECILIO; PEREIRA-LIMA, KARINA; LOUREIRO, SONIA R.. Monitoring the Mental Health and Professional Overload of Health Workers in Brazil: A Longitudinal Study Considering the First Wave of the COVID-19 Pandemic. FRONTIERS IN PSYCHIATRY, v. 13, p. 11-pg., 2022-04-08. (14/50891-1)

TOMASELLI, PEDRO J.; DOS SANTOS, DIOGO F.; DOS SANTOS, ANDRE C. J.; ANTUNES, DOUGLAS E.; MARQUES, VANESSA D.; FOSS, NORMA T.; MOREIRA, CAROLINA L.; NOGUEIRA, PATRICIA T. B.; NASCIMENTO, OSVALDO J. M.; NEDER, LUCIANO; et al. Primary neural leprosy: clinical, neurophysiological and pathological presentation and progression. BRAIN, v. 145, n. 4, p. 8-pg., 2022-03-30. (14/50891-1)

SOUZA, JOSE DIOGO S.; ZUARDI, ANTONIO W.; GUIMARAES, FRANCISCO S.; OSORIO, FLAVIA DE LIMA; LOUREIRO, SONIA REGINA; CAMPOS, ALLINE CRISTINA; HALLAK, JAIME E. C.; DOS SANTOS, RAFAEL G.; MACHADO SILVEIRA, ISABELLA LARA; PEREIRA-LIMA, KARINA; et al. Maintained anxiolytic effects of cannabidiol after treatment discontinuation in healthcare workers during the COVID-19 pandemic. FRONTIERS IN PHARMACOLOGY, v. 13, p. 9-pg., 2022-10-03. (08/09009-2, 14/50891-1, 20/12110-9)

SANTIAGO, THAYS CALISTA; PARRA, LARISSA; NANI, JOAO V.; FIDALGO, THIAGO M.; BRADSHAW, NICHOLAS J.; HAYASHI, MIRIAN A. F.. Angiotensin-converting enzymes as druggable features of psychiatric and neurodegenerative disorders. Journal of Neurochemistry, v. 166, n. 2, p. 18-pg., 2023-03-27. (19/08287-3, 22/03297-3, 19/09207-3, 19/13112-8, 20/01107-7, 22/00527-8, 17/02413-1, 14/50891-1)

OYADOMARI, WILLIAM YOSHIO; ANTHERO, GABRIEL LESSA; SILVA, MARCOS R. DE A.; PORTA, LUCAS C.; OLIVEIRA, VITOR; REID, PAUL F.; SANT'ANNA, OSVALDO A.; ALVES, WENDEL A.; NANI, JOAO, V; HAYASHI, MIRIAN AKEMI FURUIE. Evaluation of tumor growth remission in a murine model for subcutaneous solid tumors - Benefits of associating the antitumor agent crotamine with mesoporous nanosilica particles to achieve improved dosing frequency and efficacy. International Journal of Pharmaceutics, v. 646, p. 8-pg., 2023-10-05. (19/09207-3, 20/01107-7, 22/00527-8, 11/50963-4, 17/02413-1, 19/08287-3, 22/03297-3, 19/13112-8, 14/50891-1)

CARVALHO OLIVEIRA, IGOR GUSTAVO; COSTA QUEIROZ, MARIA EUGENIA. A micro salting-out assisted liquid-liquid extraction combined with ultra-high performance liquid chromatography tandem mass spectrometry to determine anandamide and 2-arachidonoylglycerol in rat brain samples. JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, v. 1158, NOV 20 2020. (14/50891-1, 17/02147-0)

LAZARINI-LOPES, WILLIAN; DO VAL-DA SILVA, RAQUEL A.; DA SILVA-JUNIOR, RUI M. P.; CUNHA, ALEXANDRA O. S.; GARCIA-CAIRASCO, NORBERTO. Cannabinoids in Audiogenic Seizures: From Neuronal Networks to Future Perspectives for Epilepsy Treatment. FRONTIERS IN BEHAVIORAL NEUROSCIENCE, v. 15, FEB 11 2021. (19/05957-8, 19/00849-2, 14/50891-1)

SILVA-CARDOSO, GLEICE K.; LAZARINI-LOPES, WILLIAN; PRIMINI, EDUARDO OCTAVIANO; HALLAK, JAIME E.; CRIPPA, JOSE A.; ZUARDI, ANTONIO W.; GARCIA-CAIRASCO, NORBERTO; LEITE-PANISSI, CHRISTIE R. A.. Cannabidiol modulates chronic neuropathic pain aversion behavior by attenuation of neuroinflammation markers and neuronal activity in the corticolimbic circuit in male Wistar rats. Behavioural Brain Research, v. 452, p. 16-pg., 2023-08-24. (21/13622-6, 19/12439-3, 22/05471-0, 18/06877-5, 14/50891-1)

HAYASHI, MIRIAN A. F.; SALVETAT, NICOLAS; CAYZAC, CHRISTOPHER; CHECA-ROBLES, FRANCISCO JESUS; DUBUC, BENJAMIN; MEREUZE, SANDIE; V. NANI, JOAO; MOLINA, FRANCK; BRIETZKE, ELISA; WEISSMANN, DINAH. Euthymic and depressed bipolar patients are characterized by different RNA editing patterns in blood. PSYCHIATRY RESEARCH, v. 328, p. 4-pg., 2023-08-27. (19/08287-3, 22/03297-3, 19/09207-3, 19/13112-8, 20/01107-7, 22/00527-8, 17/02413-1, 14/50891-1)

DE CARVALHO PORTA, LUCAS; FADEL, VALMIR; D'ARC CAMPEIRO, JOANA; OLIVEIRA, EDUARDO BRANDT; GODINHO, ROSELY OLIVEIRA; HAYASHI, MIRIAN AKEMI FURUIE. Biophysical and pharmacological characterization of a full-length synthetic analog of the antitumor polypeptide crotamine. JOURNAL OF MOLECULAR MEDICINE-JMM, v. 98, n. 11, SEP 2020. (14/50891-1, 17/02413-1, 18/20014-0, 18/21381-6)

OYADOMARI, WILLIAM Y.; CHRISTOFF, RAISSA R.; RABELLO, TAILENE; OLIVEIRA, VITOR; HIGA, LUIZA M.; GARCEZ, PATRICIA P.; HAYASHI, MIRIAN A. F.. Infection by zika virus increase angiotensin I-converting enzyme activity in mouse brain. Biochimie, v. 227, p. 3-pg., 2024-12-03. (11/50963-4, 20/01107-7, 19/13112-8, 23/07904-4, 17/02413-1, 19/08287-3, 14/50891-1, 22/03297-3, 19/09207-3, 22/00527-8)

NANI, JOAO V.; COELHO, CAMILA; OYADOMARI, WILLIAM Y.; SANTIAGO, THAYS CALISTA; MACHADO, MARCELO MARCONDES; CHRISTOFF, RAISSA R.; GARCEZ, PATRICIA P.; OLIVEIRA, VITOR; WURTELE, MARTIN; HAYASHI, MIRIAN A. F.. Identification of an ex vivo inhibitor of the schizophrenia biomarker Ndel1 by high throughput screening. Biochemical Pharmacology, v. 217, p. 11-pg., 2023-10-14. (19/09207-3, 23/07904-4, 20/01107-7, 22/00527-8, 11/50963-4, 17/02413-1, 19/08287-3, 22/03297-3, 19/13112-8, 14/50891-1)

NANI, JOAO VICTOR; USHIROHIRA, JULIANA MAYUMI; BRADSHAW, NICHOLAS J.; MACHADO-DE-SOUSA, JOAO PAULO; HALLAK, JAIME EDUARDO CECILIO; HAYASHI, MIRIAN A. F.. Sodium nitroprusside as an adjunctive treatment for schizophrenia reduces Ndel1 oligopeptidase activity. Revista Brasileira de Psiquiatria, v. 46, p. 10-pg., 2024-01-01. (19/09207-3, 20/01107-7, 22/00527-8, 17/02413-1, 19/08287-3, 22/03297-3, 19/13112-8, 14/50891-1)

DE LIMA BOMFIM, ANA JULIA; FAVERO ZUZE, STEFANY MIRRELLE; FABRICIO, DAIENE DE MORAIS; DE PAULA PESSOA, REBECA MENDES; CRIPPA, JOSE ALEXANDRE S.; CHAGAS, MARCOS HORTES N.. Effects of the Acute and Chronic Administration of Cannabidiol on Cognition in Humans and Animals: A Systematic Review. CANNABIS AND CANNABINOID RESEARCH, v. 8, n. 6, p. 19-pg., 2023-10-04. (14/50891-1)

MAIA BEZERRA, NATHALIA KAREN; DE MENEZES GALVAO, ANA CECILIA; MARTINS LEITE, NATHALIA EVELYN; LEAO BARBALHO SANT'ANNA, ADRIANA; DE MEDEIROS GARCIA TORRES, MYCHELLE; GALVAO PINTO COELHO, MARIA CECILIA; KENJI MEDEIROS SHIRAMIZU, VICTOR; DE SOUSA, MARIA BERNARDETE CORDEIRO; LEITE GALVAO-COELHO, NICOLE. Success ofin vitrofertilization and its association with the levels of psychophysiological stress before and during the treatment. HEALTH CARE FOR WOMEN INTERNATIONAL, JUL 2020. (14/50891-1)

CORAL RAKOVSKI; TAIANE DE AZEVEDO CARDOSO; JUREMA CORRÊA DA MOTA; FRANCISCO I. BASTOS; FLAVIO KAPCZINSKI; RAQUEL BRANDINI DE BONI. Underage drinking in Brazil: findings from a community household survey. Revista Brasileira de Psiquiatria, 2021-12-15. (14/50891-1)

VALIM BRIGANTE, TAMIRES AMABILE; ABE, FLAVIA R.; ZUARDI, ANTONIO WALDO; CECILIO HALLAK, JAIME EDUARDO; CRIPPA, JOSE ALEXANDRE S.; DE OLIVEIRA, DANIELLE P.. Cannabidiol did not induce teratogenicity or neurotoxicity in exposed zebrafish embryos. Chemico-Biological Interactions, v. 291, p. 81-86, AUG 1 2018. (14/50891-1, 16/03281-9)

SILVA-CARDOSO, GLEICE K.; LAZARINI-LOPES, WILLIAN; HALLAK, JAIME E.; CRIPPA, JOSE A.; ZUARDI, ANTONIO W.; GARCIA-CAIRASCO, NORBERTO; LEITE-PANISSI, CHRISTIE R. A.. Cannabidiol effectively reverses mechanical and thermal allodynia, hyperalgesia, and anxious behaviors in a neuropathic pain model: Possible role of CB1 and TRPV1 receptors. Neuropharmacology, v. 197, OCT 1 2021. (19/05957-8, 18/06877-5, 14/50891-1)

VALENTIM-LIMA, EVANDRO; DE OLIVEIRA, JOSE ANTONIO CORTES; ANTUNES-RODRIGUES, JOSE.; REIS, LUIS CARLOS; GARCIA-CAIRASCO, NORBERTO; MECAWI, ANDRE S.. Neuroendocrine changes in the hypothalamic-neurohypophysial system in the Wistar audiogenic rat (WAR) strain submitted to audiogenic kindling. Journal of Neuroendocrinology, v. 33, n. 7, SI, JUL 2021. (19/05957-8, 14/50891-1, 14/15218-4, 13/09799-1)

ALVES, SUELEN SANTOS; PATRICIO DA SILVA-JUNIOR, RUI MILTON; SERVILHA-MENEZES, GABRIEL; HOMOLAK, JAN; SALKOVIC-PETRISIC, MELITA; GARCIA-CAIRASCO, NORBERTO. Insulin Resistance as a Common Link Between Current Alzheimer's Disease Hypotheses. JOURNAL OF ALZHEIMER'S DISEASE, v. 82, n. 1, p. 71-105, 2021. (19/00849-2, 19/05957-8, 14/50891-1, 19/02787-4)

OSORIO, FLAVIA L.; MACHADO SILVEIRA, ISABELLA LARA; PEREIRA-LIMA, KARINA; DE SOUZA CRIPPA, JOSE ALEXANDRE; CECILIO HALLAK, JAIME EDUARDO; ZUARDI, ANTONIO WALDO; LOUREIRO, SONIA REGINA. Risk and Protective Factors for the Mental Health of Brazilian Healthcare Workers in the Frontline of COVID-19 Pandemic. FRONTIERS IN PSYCHIATRY, v. 12, JUL 28 2021. (14/50891-1)

SERVILHA-MENEZES, GABRIEL; GARCIA-CAIRASCO, NORBERTO. A complex systems view on the current hypotheses of epilepsy pharmacoresistance. EPILEPSIA OPEN, v. N/A, p. 15-pg., 2022-03-11. (19/02787-4, 19/05957-8, 14/50891-1)

ALVES, SUELEN SANTOS; PATRICIO DA SILVA JUNIOR, RUI MILTON; DELFINO-PEREIRA, POLIANNA; ALVES GOULART PEREIRA, MARILIA GABRIELLA; VASCONCELOS, ISRAEL; SCHWAEMMLE, HANNA; MAZZEI, RODRIGO FOCOSI; CARLOS, MAIKO LUIZ; ESPREAFICO, ENILZA MARIA; TEDESCO, ANTONIO CLAUDIO; et al. A Genetic Model of Epilepsy with a Partial Alzheimer's Disease-Like Phenotype and Central Insulin Resistance. Molecular Neurobiology, v. 59, n. 6, p. 17-pg., 2022-04-04. (19/05957-8, 14/50891-1, 19/16574-2, 19/02787-4, 19/00849-2, 17/21155-3)

TROMBETTA-LIMA, MARINA; ASSIS-RIBAS, THAIS; CINTRA, RICARDO C.; CAMPEIRO, JOANA D.; GUERREIRO, JULIANO R.; WINNISCHOFER, SHEILA M. B.; NASCIMENTO, ISIS C. C.; ULRICH, HENNING; HAYASHI, MIRIAN A. F.; SOGAYAR, MARI C.. Impact of Reck expression and promoter activity in neuronal in vitro differentiation. MOLECULAR BIOLOGY REPORTS, v. 48, n. 2, FEB 2021. (18/20014-0, 16/05311-2, 18/07366-4, 14/50891-1, 19/13112-8, 15/26328-8, 16/18277-7, 12/50880-4, 17/02413-1)

RODRIGUEZ, BENJAMIN; NANI, JOAO VICTOR; ALMEIDA, PRISCILA G. C.; BRIETZKE, ELISA; LEE, RICHARD S.; HAYASHI, MIRIAN A. F.. Neuropeptides and oligopeptidases in schizophrenia. NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS, v. 108, p. 679-693, JAN 2020. (14/50867-3, 14/50891-1, 17/02413-1, 14/18938-8, 19/09207-3)

LAZARINI-LOPES, WILLIAN; DA SILVA-JUNIOR, RUI M. P.; SERVILHA-MENEZES, GABRIEL; DO VAL-DA SILVA, RAQUEL A.; GARCIA-CAIRASCO, NORBERTO. Cannabinoid Receptor Type 1 (CB1R) Expression in Limbic Brain Structures After Acute and Chronic Seizures in a Genetic Model of Epilepsy. FRONTIERS IN BEHAVIORAL NEUROSCIENCE, v. 14, DEC 21 2020. (19/00849-2, 19/02787-4, 14/50891-1, 19/05957-8)

TASIC, LJUBICA; LARCERDA, ACIOLY L. T.; PONTES, JOAO G. M.; DA COSTA, TASSIA B. B. C.; NANI, V, JOAO; MARTINS, LUCAS GELAIN; SANTOS, LEONARDO A.; NUNES, MARIELLE F. Q.; ADELINO, MARCELO P. M.; PEDRINI, MARIANA; et al. Peripheral biomarkers allow differential diagnosis between schizophrenia and bipolar disorder. JOURNAL OF PSYCHIATRIC RESEARCH, v. 119, p. 67-75, DEC 2019. (14/50867-3, 14/50891-1, 14/18938-8)

TILELLI, CRISTIANE QUEIXA; FLORES, LARISSA RIBEIRO; COTA, VINICIUS ROSA; DE CASTRO, OLAGIDE WAGNER; GARCIA-CAIRASCO, NORBERTO. Amygdaloid complex anatomopathological findings in animal models of status epilepticus. Epilepsy & Behavior, v. 121, n. B, AUG 2021. (14/50891-1, 19/05957-8)

OSORIO, FLAVIA L.; LOUREIRO, SONIA REGINA; HALLAK, JAIME EDUARDO C.; MACHADO-DE-SOUSA, JOAO PAULO; USHIROHIRA, JULIANA M.; BAES, CRISTIANE V. W.; APOLINARIO, THIAGO D.; DONADON, MARIANA F.; BOLSONI, LIVIA M.; GUIMARAES, THIAGO; et al. Clinical validity and intrarater and test-retest reliability of the Structured Clinical Interview for DSM-5-Clinician Version (SCID-5-CV). PSYCHIATRY AND CLINICAL NEUROSCIENCES, v. 73, n. 12, p. 754-760, DEC 2019. (14/50891-1, 17/18000-8)

NANI, V, JOAO; ALMEIDA, PRISCILA G. C.; NOTO, CRISTIANO; BRESSAN, RODRIGO A.; BRIETZKE, ELISA; HAYASHI, MIRIAN A. F.. Unraveiling the correlation among neurodevelopmental and inflammatory biomarkers in patients with chronic schizophrenia. NORDIC JOURNAL OF PSYCHIATRY, JAN 2022. (19/09207-3, 18/20014-0, 17/02413-1, 14/50891-1)

BALLESTER, PEDRO L.; CARDOSO, TAIANE DE A.; MOREIRA, FERNANDA PEDROTTI; SILVA, RICARDO A. DA; MONDIN, THAISE CAMPOS; ARAUJO, RICARDO M.; KAPCZINSKI, FLAVIO; FREY, BENICIO N.; JANSEN, KAREN; SOUZA, LUCIANO D. DE MATTOS. 5-year incidence of suicide-risk in youth: A gradient tree boosting and SHAP study. Journal of Affective Disorders, v. 297, p. 1049-1056, JAN 15 2022. (14/50891-1)

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