Formação e propriedades de hemiésteres do ácido carbônico em meio aquoso

• Processo: 17/13137-5
• Modalidade de apoio: Auxílio à Pesquisa - Temático
• Data de Início da vigência: 01 de abril de 2018
• Data de Término da vigência: 31 de março de 2023
• Área do conhecimento: Ciências Exatas e da Terra - Química - Química Analítica
• Pesquisador responsável: Claudimir Lucio Do Lago
• Beneficiário: Claudimir Lucio Do Lago
• Instituição Sede: Instituto de Química (IQ). Universidade de São Paulo (USP). São Paulo , SP, Brasil
• Pesquisadores principais: Lucio Angnes
• Pesquisadores associados: Ivano Gebhardt Rolf Gutz ; Lucas Colucci Ducati ; Lucio Angnes ; Rômulo Augusto Ando ; Sandro Roberto Marana
• Bolsa(s) vinculada(s): 19/22126-2 - Comportamento eletroquímico de hemiésteres do ácido carbônico em meio aquoso, BP.DR; 18/23768-5 - Hemiésteres do Ácido Carbônico: Compostos Nitrogenados e de Membrana, BP.PD; 19/01207-4 - Utilização de recursos de CAD e CAM para produção de dispositivos de interesse em química analítica, BP.TT; 18/20764-9 - Utilização de sistemas de eletroforese capilar com detecção condutométrica sem contato e espectrometria de massas, BP.TT; 18/13960-6 - Desenvolvimento de instrumentação para detecção e caracterização de hemiésteres do ácido carbônico, BP.PD
• Assunto(s): Química teórica Bioquímica Instrumentação analítica Ácido carbônico Membrana celular
• Palavra(s)-Chave do Pesquisador: Eletroforese Capilar | Espectrometria de massas | hemiésteres do ácido carbônico | Instrumentação Analítica | monoalquilcarbonatos | Ressonância Magnética Nuclear | instrumentação analítica

Resumo

Ao longo dos últimos anos, temos estudado os hemiésteres do ácido carbônico (HECAs) formados espontaneamente em meio aquoso a partir de HCO3-/CO2 e um composto apresentando ao menos um grupo álcool. Em projeto anteriormente financiado pela FAPESP (2012/06642-1), pudemos promover um avanço significativo na compreensão do processo de formação destas espécies. Nesta nova fase, pretendemos estender os estudos em várias direções: 1) detecção e propriedades de HECAs de compostos de membrana celular; 2) avaliação da acidez dos álcoois alquilcarbônicos; 3) identificação de enzimas que catalisem a formação de HECAs; 4) HECAs de aminoálcoois de interesse bioquímico e industrial e 5) comportamento eletroquímico de HECAs. A equipe de trabalho é diversificada, sendo composta por especialistas indo de Química Teórica a Bioquímica. Nossa expectativa é a de que possamos desenvolver técnicas analíticas apropriadas e demonstrar a importância desta classe de compostos em processos naturais e industriais. (AU)

Publicações científicas

(44)

(Referências obtidas automaticamente do Web of Science e do SciELO, por meio da informação sobre o financiamento pela FAPESP e o número do processo correspondente, incluída na publicação pelos autores)

GONCALVES, JOSUE M.; DA SILVA, MATHEUS I.; HASHEMINEJAD, MEISAM; TOMA, HENRIQUE E.; ARAKI, KOITI; MARTINS, PAULO R.; ANGNES, LUCIO. Recent Progress in Core@Shell Sulfide Electrode Materials for Advanced Supercapacitor Devices. BATTERIES & SUPERCAPS, MAR 2021. (13/24725-4, 18/21489-1, 18/16896-7, 14/50867-3, 17/13137-5)

SURKOV, ANDREI M.; QUEIROZ, RODRIGO G.; RINCO, RAFAEL S.; RIOS, ALEJANDRO G.; GUTZ, IVANO G. R.; BACCARO, ALEXANDRE L. B.; ANGNES, LUCIO. Graphite-polystyrene composite with enhanced electrochemical and electroanalytical performance. Talanta, v. 223, n. 2, FEB 1 2021. (17/13137-5, 14/50867-3)

AMEKU, WILSON A.; NEGAHDARY, MASOUD; LIMA, IRLAN S.; SANTOS, BERLANE G.; OLIVEIRA, THAWAN G.; PAIXAO, THIAGO R. L. C.; ANGNES, LUCIO. Laser-Scribed Graphene-Based Electrochemical Sensors: A Review. CHEMOSENSORS, v. 10, n. 12, p. 31-pg., 2022-12-01. (18/16896-7, 19/22126-2, 14/50867-3, 17/13137-5)

GONCALVES, JOSUE M.; DE FARIA, LUCAS, V; NASCIMENTO, AMANDA B.; GERMSCHEIDT, RAFAEL L.; PATRA, SANTANU; HERNANDEZ-SARAVIA, LUCAS P.; BONACIN, JULIANO A.; MUNOZ, RODRIGO A. A.; ANGNES, LUCIO. Sensing performances of spinel ferrites MFe2O4 (M = Mg, Ni, Co, Mn, Cu and Zn) based electrochemical sensors: A review. Analytica Chimica Acta, v. 1233, p. 31-pg., 2022-10-22. (13/22127-2, 18/16896-7, 17/13137-5, 20/00325-0, 14/50867-3)

GONCALVES, JOSUE M.; HENNEMANN, ARTUR LUIS; RUIZ-MONTOYA, JOSE G.; MARTINS, PAULO R.; ARAKI, KOITI; ANGNES, LUCIO; SHAHBAZIAN-YASSAR, REZA. Metal-glycerolates and their derivatives as electrode materials: A review on recent developments, challenges, and future perspectives. Coordination Chemistry Reviews, v. 477, p. 29-pg., 2023-02-15. (18/16896-7, 18/21489-1, 17/13137-5, 13/24725-4, 20/06176-7)

AZEREDO, NATHALIA F. B.; GONCALVES, JOSUE M.; ROSSINI, PAMELA O.; ARAKI, KOITI; WANG, JOSEPH; ANGNES, LUCIO. Uric acid electrochemical sensing in biofluids based on Ni/Zn hydroxide nanocatalyst. Microchimica Acta, v. 187, n. 7, JUN 9 2020. (14/50867-3, 17/13137-5, 18/21489-1, 18/16896-7)

GONCALVES, JOSUE M.; MATIAS, TIAGO A.; ANGNES, LUCIO; MARTINS, PAULO R.; ARAKI, KOITI. Review-Tetraruthenated Porphyrins and Composites as Catalysts and Sensor Materials: A Short Review. ECS JOURNAL OF SOLID STATE SCIENCE AND TECHNOLOGY, v. 9, n. 6, JAN 8 2020. (13/24725-4, 18/16896-7, 17/13137-5, 18/21489-1, 17/50129-0, 14/50867-3)

GONCALVES, JOSUE M.; KUMAR, ABHISHEK; DA SILVA, MATHEUS I.; TOMA, HENRIQUE E.; MARTINS, PAULO R.; ARAKI, KOITI; BERTOTTI, MAURO; ANGNES, LUCIO. Nanoporous Gold-Based Materials for Electrochemical Energy Storage and Conversion. ENERGY TECHNOLOGY, v. 9, n. 5, MAR 2021. (18/16896-7, 17/13137-5, 18/21489-1)

KUMAR, ABHISHEK; GONCALVES, JOSUE M.; LUDER, JOHANN; NAKAMURA, MARCELO; ANGNES, LUCIO; BOUVET, MARCEL; BERTOTTI, MAURO; ARAKI, KOITI. Interplay of hetero-MN4 catalytic sites on graphene for efficient oxygen reduction reaction. Electrochimica Acta, v. 419, p. 12-pg., 2022-07-01. (17/13137-5, 19/14418-3)

CERDEIRA FERREIRA, LUIS MARCOS; MARTINS, PAULO ROBERTO; ARAKI, KOITI; ANGNES, LUCIO. Tuning Selectivity and Sensitivity of Mixed-polymeric Tetraruthenated Metalloporphyrins Modified Electrodes as Voltammetric Sensors of Chloramphenicol. Electroanalysis, v. 31, n. 4, p. 688-694, APR 2019. (17/13137-5)

GONCALVES, JOSUE M.; ROCHA, DIEGO P.; SILVA, MURILLO N. T.; MARTINS, PAULO R.; NOSSOL, EDSON; ANGNES, LUCIO; ROUT, CHANDRA SEKHAR; MUNOZ, RODRIGO A. A.. Feasible strategies to promote the sensing performances of spinel MCo2O4 (M = Ni, Fe, Mn, Cu and Zn) based electrochemical sensors: a review. JOURNAL OF MATERIALS CHEMISTRY C, v. 9, n. 25, p. 7852-7887, JUL 7 2021. (17/13137-5, 18/16896-7, 14/50867-3, 20/00325-0)

NEGAHDARY, MASOUD; AMEKU, WILSON AKIRA; SANTOS, BERLANE GOMES; LIMA, IRLAN DOS SANTOS; DE OLIVEIRA, THAWAN GOMES; FRANCA, MESAQUE CARVALHO; ANGNES, LUCIO. Recent electrochemical sensors and biosensors for toxic agents based on screen-printed electrodes equipped with nanomaterials. Microchemical Journal, v. 185, p. 18-pg., 2023-02-01. (14/50867-3, 19/27021-4, 17/13137-5)

ROSSINI, PAMELA DE O.; LAZA, ANABEL; AZEREDO, NATHALIA F. B.; GONCALVES, JOSUE M.; FELIX, FABIANA S.; ARAKI, KOITI; ANGNES, LUCIO. Ni-based double hydroxides as electrocatalysts in chemical sensors: A review. TRAC-TRENDS IN ANALYTICAL CHEMISTRY, v. 126, MAY 2020. (18/21489-1, 14/50867-3, 17/13137-5, 18/16896-7)

GONCALVES, JOSUE M.; DA SILVA, MATHEUS I.; HASHEMINEJAD, MEISAM; TOMA, HENRIQUE E.; ARAKI, KOITI; MARTINS, PAULO R.; ANGNES, LUCIO. Recent Progress in Core@Shell Sulfide Electrode Materials for Advanced Supercapacitor Devices. BATTERIES & SUPERCAPS, v. 4, n. 9, p. 1397-1427, SEP 2021. (18/21489-1, 18/16896-7, 14/50867-3, 13/24725-4, 17/13137-5)

NEGAHDARY, MASOUD; ANGNES, LUCIO. lectrochemical nanobiosensors equipped with peptides: a revie. Microchimica Acta, v. 189, n. 3, MAR 2022. (17/13137-5, 14/50867-3, 19/27021-4)

GONCALVES, JOSUE M.; IGLESIAS, BERNARDO A.; MARTINS, PAULO R.; ANGNES, LUCIO. Recent advances in electroanalytical drug detection by porphyrin/phthalocyanine macrocycles: developments and future perspectives. ANALYST, v. 146, n. 2, p. 365-381, JAN 21 2021. (18/16896-7, 17/13137-5, 14/50867-3)

NEGAHDARY, MASOUD; VELOSO, WILLIAM BARROS; BACIL, RAPHAEL PRATA; BUORO, RAFAEL MARTOS; GUTZ, IVANO GEBHARDT ROLF; PAIXAO, THIAGO REGIS LONGO CESAR; DO LAGO, CLAUDIMIR LUCIO; SAKATA, SOLANGE KAZUMI; MELONI, GABRIEL NEGRAO; FRANCA, MESAQUE CARVALHO; et al. Aptasensing of beta-amyloid (Aβ_(1-42)) by a 3D-printed platform integrated with leaf-shaped gold nanodendrites. SENSORS AND ACTUATORS B-CHEMICAL, v. 393, p. 11-pg., 2023-10-15. (19/27021-4, 17/13137-5, 18/08782-1, 14/50867-3)

GONCALVES, JOSUE M.; SILVA, MURILLO N. T.; NAIK, KUSHA KUMAR; MARTINS, PAULO R.; ROCHA, DIEGO P.; NOSSOL, EDSON; MUNOZ, RODRIGO A. A.; ANGNES, LUCIO; ROUT, CHANDRA SEKHAR. Multifunctional spinel MnCo₂O₄ based materials for energy storage and conversion: a review on emerging trends, recent developments and future perspectives. JOURNAL OF MATERIALS CHEMISTRY A, v. 9, n. 6, p. 31-pg., 2021-02-16. (18/16896-7, 20/00325-0, 17/13137-5, 14/50867-3)

DA COSTA, ERIC TAVARES; OLIVEIRA, DANIEL ROSSADO; DO LAGO, CLAUDIMIR LUCIO. Qualitative and quantitative aspects of time-, charge-, and mobility-based electropherograms. ELECTROPHORESIS, v. 43, n. 23-24, p. 14-pg., 2022-09-03. (18/13960-6, 12/06642-1, 17/13137-5)

NEGAHDARY, MASOUD; BUORO, RAFAEL MARTOS; BACIL, RAPHAEL PRATA; SANTOS, BERLANE GOMES; ANGNES, LUCIO. Design of an electrochemical aptasensor in the presence of an array of gold nanostructure and a GO-MWCNTs nanocomposite: application in diagnosis of Alzheimer's disease. Microchimica Acta, v. 190, n. 10, p. 13-pg., 2023-10-01. (19/27021-4, 17/13137-5, 14/50867-3)

NEGAHDARY, MASOUD; ANGNES, LUCIO. Recent advances in electrochemical nanomaterial-based aptasensors for the detection of cancer biomarkers. Talanta, v. 259, p. 24-pg., 2023-04-14. (19/27021-4, 17/13137-5, 14/50867-3)

NEGAHDARY, MASOUD; BARROS AZEREDO, NATHALIA FLORENCIA; SANTOS, BERLANE GOMES; DE OLIVEIRA, THAWAN GOMES; DE OLIVEIRA LINS, RENATO SOARES; DOS SANTOS LIMA, IRLAN; ANGNES, LUCIO. Electrochemical Nanomaterial-based Sensors/Biosensors for Drug Monitoring. CURRENT TOPICS IN MEDICINAL CHEMISTRY, v. 23, n. 4, p. 21-pg., 2023-01-01. (19/22126-2, 19/27021-4, 17/13137-5, 14/50867-3)

SURKOV, ANDREI M.; QUEIROZ, RODRIGO G.; RINCO, RAFAEL S.; RIOS, ALEJANDRO G.; GUTZ, IVANO G. R.; BACCARO, ALEXANDRE L. B.; ANGNES, LUCIO. Graphite-polystyrene composite with enhanced electrochemical and electroanalytical performance. Talanta, v. 223, p. 9-pg., 2021-02-01. (17/13137-5, 14/50867-3)

CLAUDIMIR LUCIO DO LAGO. A HISTORY OF CARBONIC ACID AND THE CENTRAL ROLE OF BICARBONATE IN THE CO2/H2O SYSTEM. Química Nova, v. 47, n. 8, 2024-05-03. (17/13137-5)

GONCALVES, JOSUE M.; GHORBANI, ALIREZA; RITTER, TIMOTHY G.; LIMA, IRLAN S.; SARAY, MAHMOUD TAMADONI; PHAKATKAR, ABHIJIT H.; SILVA, VINICIUS D.; PEREIRA, RAFAEL S.; YARIN, ALEXANDER L.; ANGNES, LUCIO; et al. Multimetallic glycerolate as a precursor template of spherical porous high-entropy oxide microparticles. Journal of Colloid and Interface Science, v. 641, p. 10-pg., 2023-03-22. (18/16896-7, 20/06176-7, 17/13137-5, 22/04127-4)

PHAKATKAR, ABHIJIT H.; GONCALVES, JOSUE M.; ZHOU, JIANSHU; RITTER, TIMOTHY G.; SARAY, MAHMOUD TAMADONI; SOROKINA, LIOUDMILA V.; AMIRI, AZADEH; ANGNES, LUCIO; SHOKUHFAR, TOLOU; SHAHBAZIAN-YASSAR, REZA. Enhanced Bacterial Growth by Polyelemental Glycerolate Particles. ACS APPLIED BIO MATERIALS, v. 6, n. 4, p. 10-pg., 2023-03-18. (18/16896-7, 20/06176-7, 17/13137-5)

NEGAHDARY, MASOUD; SHARMA, ABHINAV; ANTHOPOULOS, THOMAS D.; ANGNES, LUCIO. Recent advances in electrochemical nanobiosensors for cardiac biomarkers. TRAC-TRENDS IN ANALYTICAL CHEMISTRY, v. 164, p. 22-pg., 2023-07-01. (19/27021-4, 17/13137-5, 14/50867-3)

SHARMA, ABHINAV; ANGNES, LUCIO; SATTARAHMADY, NAGHMEH; NEGAHDARY, MASOUD; HELI, HOSSEIN. Electrochemical Immunosensors Developed for Amyloid-Beta and Tau Proteins, Leading Biomarkers of Alzheimer's Disease. BIOSENSORS-BASEL, v. 13, n. 7, p. 28-pg., 2023-07-01. (19/27021-4, 17/13137-5, 14/50867-3)

GONCALVES, JOSUE M.; MARTINS, PAULO R.; ROCHA, DIEGO P.; MATIAS, TIAGO A.; JULIAO, MURILO S. S.; MUNOZ, RODRIGO A. A.; ANGNES, LUCIO. Recent trends and perspectives in electrochemical sensors based on MOF-derived materials. JOURNAL OF MATERIALS CHEMISTRY C, v. 9, n. 28, p. 8718-8745, JUL 28 2021. (14/50867-3, 17/13137-5, 18/16896-7, 20/00325-0)

DANIEL, DANIELA; LOPES, FERNANDO SILVA; DO LAGO, CLAUDIMIR LUCIO. A sensitive multiresidue method for the determination of pesticides in marijuana by liquid chromatography-tandem mass spectrometry. Journal of Chromatography A, v. 1603, p. 231-239, OCT 2019. (17/13137-5, 12/06642-1)

GONCALVES, JOSUE M.; LIMA, IRLAN S.; AZEREDO, NATHALIA F. B.; ROCHA, DIEGO P.; DE SIERVO, ABNER; ANGNES, LUCIO. iVCe-Layered Double Hydroxide as Multifunctional Nanomaterials for Energy and Sensor Application. FRONTIERS IN MATERIALS, v. 8, NOV 29 2021. (17/13137-5, 20/00325-0, 07/08244-5, 07/54829-5, 18/16896-7, 14/50867-3)

SANTOS, BERLANE G.; GONCALVES, JOSUE M.; ROCHA, DIEGO P.; HIGINO, GIANE S.; YADAV, THAKUR P.; PEDROTTI, JAIRO J.; AJAYAN, PULICKEL M.; ANGNES, LUCIO. Electrochemical sensor for isoniazid detection by using a WS2/CNTs nanocomposite. SENSORS AND ACTUATORS REPORTS, v. 4, NOV 2022. (19/22126-2, 12/50259-8, 18/16896-7, 17/13137-5, 14/50867-3, 20/00325-0)

ABREU, JULIANA CALDEIRA; MAHR, AMANDA GUIRALDELLI; DO LAGO, CLAUDIMIR LUCIO. Stability-indicating method development for quantification of bromopride, its impurities, and degradation products by ultra-high performance liquid chromatography applying Analytical Quality by Design principles. Journal of Pharmaceutical and Biomedical Analysis, v. 205, OCT 25 2021. (17/13137-5, 12/06642-1)

GONCALVES, JOSUE M.; SILVA, MURILLO N. T.; NAIK, KUSHA KUMAR; MARTINS, PAULO R.; ROCHA, DIEGO P.; NOSSOL, EDSON; MUNOZ, RODRIGO A. A.; ANGNES, LUCIO; ROUT, CHANDRA SEKHAR. Multifunctional spinel MnCo2O4 based materials for energy storage and conversion: a review on emerging trends, recent developments and future perspectives. JOURNAL OF MATERIALS CHEMISTRY A, v. 9, n. 6, p. 3095-3124, FEB 14 2021. (14/50867-3, 20/00325-0, 18/16896-7, 17/13137-5)

GONCALVES, JOSUE M.; DA SILVA, MATHEUS L.; TOMA, HENRIQUE E.; ANGNES, LUCIO; MARTINS, PAULO R.; ARAKI, KOITI. Trimetallic oxides/hydroxides as hybrid supercapacitor electrode materials: a review. JOURNAL OF MATERIALS CHEMISTRY A, v. 8, n. 21, p. 10534-10570, JUN 7 2020. (18/21489-1, 17/13137-5, 18/16896-7)

FELIX, FABIANA S.; BACCARO, ALEXANDRE L. B.; ANGNES, LUCIO. Disposable Voltammetric Immunosensors Integrated with Microfluidic Platforms for Biomedical, Agricultural and Food Analyses: A Review. SENSORS, v. 18, n. 12, DEC 2018. (17/13137-5)

AGUIRRE-ARAQUE, JUAN S.; GONCALVES, JOSUE M.; NAKAMURA, MARCELO; ROSSINI, PAMELA O.; ANGNES, LUCIO; ARAKI, KOITI; TOMA, HENRIQUE E.. GO composite encompassing a tetraruthenated cobalt porphyrin-Ni coordination polymer and its behavior as isoniazid BIA sensor. Electrochimica Acta, v. 300, p. 113-122, MAR 20 2019. (13/24725-4, 17/13137-5)

AZEREDO, NATHALIA F. B.; ROSSINI, PAMELA O.; GONCALVES, JOSUE M.; ASSIS, GEOVANNE L.; ARAKI, KOITI; ANGNES, LUCIO. Nanostructured mixed Ni/Pt hydroxides electrodes for BIA-amperometry determination of hydralazine. Journal of the Taiwan Institute of Chemical Engineers, v. 95, p. 475-480, FEB 2019. (17/13137-5)

NEGAHDARY, MASOUD; ANGNES, LUCIO. Application of electrochemical biosensors for the detection of microRNAs (miRNAs) related to cancer. Coordination Chemistry Reviews, v. 464, p. 26-pg., 2022-08-01. (14/50867-3, 17/13137-5, 19/27021-4)

BALDO, THAISA APARECIDA; PROENCA, CAMILA DOS ANJOS; FELIX, FABIANA DA SILVA; FREITAS, TAYANE AGUIAR; SAKATA, SOLANGE KAZUMI; ANGNES, LUCIO; FARIA, RONALDO CENSI. Disposable electrochemical microfluidic device for ultrasensitive detection of egg allergen in wine samples. Talanta, v. 232, SEP 1 2021. (13/14262-7, 17/24053-7, 16/00991-5, 14/50867-3, 17/13137-5)

OLIVEIRA, THAWAN G.; SANTOS, BERLANE G.; GONCALVES, JOSUE M.; ANGNES, LUCIO. Amperometric detection of indapamide on glassy carbon electrode. Electroanalysis, v. 35, n. 9, p. 9-pg., 2023-05-11. (18/16896-7, 17/13137-5, 14/50867-3)

ATAIDE, VANESSA N.; PRADELA-FILHO, LAURO A.; AMEKU, WILSON A.; NEGAHDARY, MASOUD; OLIVEIRA, THAWAN G.; SANTOS, BERLANE G.; PAIXAO, THIAGO R. L. C.; ANGNES, LUCIO. Paper-based electrochemical biosensors for the diagnosis of viral diseases. Microchimica Acta, v. 190, n. 7, p. 17-pg., 2023-07-01. (19/22126-2, 18/16896-7, 18/08782-1, 14/50867-3, 21/00205-8, 18/14462-0, 17/13137-5)

SANTANA, MICHELE ALVES; LAGO, CLAUDIMIR LUCIO DO. Indirect calibration for capillary electrophoresis with conductivity detection. Analytica Chimica Acta, v. 1158, MAY 8 2021. (12/06642-1, 17/13137-5)

NEGAHDARY, MASOUD; HIRATA, MARIO HIROYUKI; SAKATA, SOLANGE KAZUMI; CICONELLI, ROZANA MESQUITA; BASTOS, GISELE MEDEIROS; BORGES, JESSICA BASSANI; THUROW, HELENA STRELOW; JUNIOR, ALCEU TOTTI SILVEIRA; SAMPAIO, MARCELO FERRAZ; GUIMARAES, LARISSA BERRETTA; et al. Sandwich-like electrochemical aptasensing of heat shock protein 70 kDa (HSP70): Application in diagnosis/prognosis of coronavirus disease 2019 (COVID-19). Analytica Chimica Acta, v. 1242, p. 10-pg., 2023-02-15. (19/27021-4, 17/13137-5, 14/50867-3)