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AJALLA ALEIXO, MARIANA A.; RANGEL, VICTOR L.; RUSTIGUEL, JOANE K.; DE PADUA, RICARDO A. P.; NONATO, MARIA CRISTINA. Structural, biochemical and biophysical characterization of recombinant human fumarate hydratase. FEBS Journal, v. 286, n. 10, p. 1925-1940, MAY 2019. Citações Web of Science: 1. (12/25075-0)
AZEREDO, LUIS FELIPE S. P.; COUTINHO, JULIA P.; JABOR, VALQUIRIA A. P.; FELICIANO, PATRICIA R.; NONATO, MARIA CRISTINA; KAISER, CARLOS R.; MENEZES, CARLA MARIA S.; HAMMES, AMANDA S. O.; CAFFARENA, ERNESTO RAUL; HOELZ, LUCAS V. B.; et al. Evaluation of 7-arylaminopyrazolo[1,5-a]pyrimidines as anti-Plasmodium falciparum, antimalarial, and Pf-dihydroorotate dehydrogenase inhibitors. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, v. 126, p. 72-83, JAN 27 2017. Citações Web of Science: 18. (12/25075-0)
FELICIANO, PATRICIA R.; RUSTIGUEL, JOANE K.; SOARES, RICARDO O. S.; SAMPAIO, SUELY V.; CRISTINA NONATO, M.. Crystal structure and molecular dynamics studies of L-amino acid oxidase from Bothrops atrox. Toxicon, v. 128, p. 50-59, MAR 15 2017. Citações Web of Science: 8. (15/24010-0, 09/10454-3, 13/14988-8)
PERES, RAPHAEL S.; SANTOS, GABRIELA B.; CECILIO, NERRY T.; JABOR, VALQURIA A. P.; NIEHUES, MICHAEL; TORRES, BRUNA G. S.; BUQUI, GABRIELA; SILVA, CARLOS H. T. P.; DALLA COSTA, TERESA; LOPES, NORBERTO P.; et al. Lapachol, a compound targeting pyrimidine metabolism, ameliorates experimental autoimmune arthritis. ARTHRITIS RESEARCH & THERAPY, v. 19, MAR 7 2017. Citações Web of Science: 6. (12/20990-2, 12/25075-0, 13/08216-2, 14/50265-3, 09/54014-7)
REIS, RENATA A. G.; CALIL, FELIPE ANTUNES; FELICIANO, PATRICIA ROSA; PINHEIRO, MATHEUS PINTO; NONATO, M. CRISTINA. The dihydroorotate dehydrogenases: Past and present. Archives of Biochemistry and Biophysics, v. 632, n. SI, p. 175-191, OCT 15 2017. Citações Web of Science: 16. (07/08703-0, 04/12349-9, 04/14407-6, 12/25075-0, 11/23504-9, 05/58008-0)
FELICIANO, PATRICIA R.; DRENNAN, CATHERINE L.; NONATO, MARIA CRISTINA. Crystal Structures of Fumarate Hydratases from Leishmania major in a Complex with Inhibitor 2-Thiomalate. ACS Chemical Biology, v. 14, n. 2, p. 266-275, FEB 2019. Citações Web of Science: 1. (14/22246-4, 08/08262-6, 13/14988-8)
SARTIM, MARCO A.; PINHEIRO, MATHEUS P.; DE PADUA, RICARDO A. P.; SAMPAIO, SUELY V.; CRISTINA NONATO, M.. Structural and binding studies of a C-type galactose-binding lectin from Bothrops jararacussu snake venom. Toxicon, v. 126, p. 59-69, FEB 2017. Citações Web of Science: 6. (11/23236-4, 14/11266-4, 14/19127-3)
ALVES, RAQUEL MELO; FELICIANO, PATRICIA ROSA; SAMPAIO, SUELY VILELA; NONATO, MARIA CRISTINA. A rational protocol for the successful crystallization of l-amino-acid oxidase from Bothrops atrox. ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY COMMUNICATIONS, v. 67, n. 4, p. 475-478, APR 2011. Citações Web of Science: 2. (07/51700-1, 09/10454-3, 05/54855-0)
GARCIA REIS, RENATA ALMEIDA; LORENZATO, JR., EDER; SILVA, VALERIA CRISTINA; NONATO, MARIA CRISTINA. Recombinant production, crystallization and crystal structure determination of dihydroorotate dehydrogenase from Leishmania (Viannia) braziliensis. ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY COMMUNICATIONS, v. 71, n. 5, SI, p. 547-552, MAY 2015. Citações Web of Science: 2. (12/25075-0, 11/23504-9, 14/01257-8)
LEWIS, TIMOTHY A.; SYKES, DAVID B.; LAW, JASON M.; MUNOZ, BENITO; RUSTIGUEL, JOANE K.; NONATO, MARIA CRISTINA; SCADDEN, DAVID T.; SCHREIBER, STUART L.. Development of ML390: A Human DHODH Inhibitor That Induces Differentiation in Acute Myeloid Leukemia. ACS Medicinal Chemistry Letters, v. 7, n. 12, p. 1112-1117, DEC 2016. Citações Web of Science: 14. (12/25075-0)
DE PADUA, RICARDO A. P.; KIA, ALI MARTIN; COSTA-FILHO, ANTONIO J.; WILKINSON, SHANE R.; NONATO, M. CRISTINA. Characterisation of the fumarate hydratase repertoire in Trypanosoma cruzi. International Journal of Biological Macromolecules, v. 102, p. 42-51, SEP 2017. Citações Web of Science: 4. (08/11644-8, 15/18390-5, 08/08262-6)
MAETANI, MICAH; KATO, NOBUTAKA; JABOR, VALQUIRIA A. P.; CALIL, FELIPE A.; NONATO, MARIA CRISTINA; SCHERER, CHRISTINA A.; SCHREIBER, STUART L.. Discovery of Antimalarial Azetidine-2-carbonitriles That Inhibit P-falciparum Dihydroorotate Dehydrogenase. ACS Medicinal Chemistry Letters, v. 8, n. 4, p. 438-442, APR 2017. Citações Web of Science: 17. (12/25075-0)
RUSTIGUEL, JOANE K.; SOARES, RICARDO O. S.; MEISBURGER, STEVE P.; DAVIS, KATHERINE M.; MALZBENDER, KRISTINA L.; ANDO, NOZOMI; DIAS-BARUFFI, MARCELO; NONATO, MARIA CRISTINA. Full-length model of the human galectin-4 and insights into dynamics of inter-domain communication. SCIENTIFIC REPORTS, v. 6, SEP 19 2016. Citações Web of Science: 3. (10/16153-2, 11/21811-1)
RUSTIGUEL, JOANE K.; KUMAGAI, PATRICIA S.; DIAS-BARUFFI, MARCELO; COSTA-FILHO, ANTONIO J.; NONATO, MARIA CRISTINA. Recombinant expression, purification and preliminary biophysical and structural studies of C-terminal carbohydrate recognition domain from human galectin-4. Protein Expression and Purification, v. 118, p. 39-48, FEB 2016. Citações Web of Science: 3. (10/17662-8, 10/16153-2, 11/21767-2, 11/21811-1)
REIS, RENATA A. G.; FERREIRA, PATRICIA; MEDINA, MILAGROS; NONATO, M. CRISTINA. The mechanistic study of Leishmania major dihydro-orotate dehydrogenase based on steady- and pre-steady-state kinetic analysis. Biochemical Journal, v. 473, n. 5, p. 651-660, MAR 1 2016. Citações Web of Science: 5. (12/25075-0, 11/23504-9)
PEREIRA DE PADUA, RICARDO AUGUSTO; NONATO, MARIA CRISTINA. Cloning, expression, purification, crystallization and preliminary X-ray diffraction analysis of recombinant human fumarase. ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY COMMUNICATIONS, v. 70, n. 1, p. 120-122, JAN 2014. Citações Web of Science: 4. (08/11644-8, 08/08262-6)
PINHEIRO, MATHEUS PINTO; EMERY, FLAVIO DA SILVA; CRISTINA NONATO, M.. Target Sites for the Design of Anti-trypanosomatid Drugs Based on the Structure of Dihydroorotate Dehydrogenase. CURRENT PHARMACEUTICAL DESIGN, v. 19, n. 14, p. 2615-2627, APR 2013. Citações Web of Science: 18. (07/08703-0, 09/14184-0, 02/07032-0, 01/14583-0)
RUSTIGUEL, JOANE KATHELEN; PINHEIRO, MATHEUS PINTO; ULIAN ARAUJO, ANA PAULA; NONATO, MARIA CRISTINA. Crystallization and preliminary X-ray diffraction analysis of recombinant chlorocatechol 1,2-dioxygenase from Pseudomonas putida. ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY COMMUNICATIONS, v. 67, n. 4, p. 507-509, APR 2011. Citações Web of Science: 3. (08/01743-9, 08/07077-0)
CORDEIRO, ARTUR T.; FELICIANO, PATRICIA R.; PINHEIRO, MATHEUS P.; CRISTINA NONATO, M.. Crystal structure of dihydroorotate dehydrogenase from Leishmania major. Biochimie, v. 94, n. 8, p. 1739-1748, AUG 2012. Citações Web of Science: 23. (04/14407-6, 02/07032-0, 01/14583-0)
RUSTIGUEL, JOANE K.; SOARES, RICARDO O. S.; MEISBURGER, STEVE P.; DAVIS, KATHERINE M.; MALZBENDER, KRISTINA L.; ANDO, NOZOMI; DIAS-BARUFFI, MARCELO; NONATO, MARIA CRISTINA. Full-length model of the human galectin-4 and insights into dynamics of inter-domain communication. SCIENTIFIC REPORTS, v. 6, SEP 19 2016. Citações Web of Science: 3. (11/21811-1, 10/16153-2)
DE MORI, RENAN M.; ALEIXO, MARIANA A. A.; ZAPATA, LUANA C. C.; CALIL, FELIPE A.; EMERY, FLAVIO S.; NONATO, M. CRISTINA. Structural basis for the function and inhibition of dihydroorotate dehydrogenase from Schistosoma mansoni. FEBS Journal, v. 288, n. 3, JUN 2020. Citações Web of Science: 1. (15/25099-5, 19/04395-6, 19/08376-6)
CORDEIRO, ARTUR T.; FELICIANO, PATRICIA R.; PINHEIRO, MATHEUS P.; CRISTINA NONATO, M.. Crystal structure of dihydroorotate dehydrogenase from Leishmania major. Biochimie, v. 94, n. 8, p. 1739-1748, AUG 2012. Citações Web of Science: 23. (01/14583-0, 04/14407-6, 02/07032-0)
PINHEIRO, MATHEUS PINTO; EMERY, FLAVIO DA SILVA; CRISTINA NONATO, M.. Target Sites for the Design of Anti-trypanosomatid Drugs Based on the Structure of Dihydroorotate Dehydrogenase. CURRENT PHARMACEUTICAL DESIGN, v. 19, n. 14, p. 2615-2627, APR 2013. Citações Web of Science: 18. (01/14583-0, 09/14184-0, 02/07032-0, 07/08703-0)
REIS, RENATA A. G.; FERREIRA, PATRICIA; MEDINA, MILAGROS; NONATO, M. CRISTINA. The mechanistic study of Leishmania major dihydro-orotate dehydrogenase based on steady- and pre-steady-state kinetic analysis. Biochemical Journal, v. 473, n. 5, p. 651-660, MAR 1 2016. Citações Web of Science: 5. (11/23504-9, 12/25075-0)
GARCIA REIS, RENATA ALMEIDA; LORENZATO, JR., EDER; SILVA, VALERIA CRISTINA; NONATO, MARIA CRISTINA. Recombinant production, crystallization and crystal structure determination of dihydroorotate dehydrogenase from Leishmania (Viannia) braziliensis. ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY COMMUNICATIONS, v. 71, n. 5, SI, p. 547-552, MAY 2015. Citações Web of Science: 2. (14/01257-8, 11/23504-9, 12/25075-0)
RUSTIGUEL, JOANE KATHELEN; PINHEIRO, MATHEUS PINTO; ULIAN ARAUJO, ANA PAULA; NONATO, MARIA CRISTINA. Crystallization and preliminary X-ray diffraction analysis of recombinant chlorocatechol 1,2-dioxygenase from Pseudomonas putida. ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY COMMUNICATIONS, v. 67, n. 4, p. 507-509, APR 2011. Citações Web of Science: 3. (08/01743-9, 08/07077-0)
RUSTIGUEL, JOANE K.; KUMAGAI, PATRICIA S.; DIAS-BARUFFI, MARCELO; COSTA-FILHO, ANTONIO J.; NONATO, MARIA CRISTINA. Recombinant expression, purification and preliminary biophysical and structural studies of C-terminal carbohydrate recognition domain from human galectin-4. Protein Expression and Purification, v. 118, p. 39-48, FEB 2016. Citações Web of Science: 3. (11/21811-1, 11/21767-2, 10/16153-2, 10/17662-8)
PEREIRA DE PADUA, RICARDO AUGUSTO; NONATO, MARIA CRISTINA. Cloning, expression, purification, crystallization and preliminary X-ray diffraction analysis of recombinant human fumarase. ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY COMMUNICATIONS, v. 70, n. 1, p. 120-122, JAN 2014. Citações Web of Science: 4. (08/08262-6, 08/11644-8)