Márcio Luís Andrade e Silva - Biblioteca Virtual da FAPESP
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Márcio Luís Andrade e Silva

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Universidade de Franca (UNIFRAN). Reitoria  (Instituição Sede da última proposta de pesquisa)
País de origem: Brasil

MARCIO LUIS ANDRADE AND SILVA, PhD graduated with a doctorate in Sciences from the Faculty of Sciences and Letters of Ribeirão Preto USP in 1999. He completed post-doctoral training at the Pharmacognosy Laboratory of the Faculty of Pharmaceutical Sciences of Ribeirão Preto USP from 2011 to 2012. He is currently member of the University of Franca as Professor Researcher in RDIDP regime. He has published 143 articles in specialized journals and 185 papers in annals of events. He participated in the development of 15 technological products. Participated in 9 events abroad and 24 in Brazil. He directed 22 Master's Dissertations and 4 Doctoral Theses. At present, he has three doctorates and two master's degrees, in addition to having supervised 20 scientific initiation works and 7 graduation papers in the areas of Pharmacy, Chemistry and Collective Health. Supervised 3 post-doctoral stages, 2 with FAPESP scholarship and 1 with CNPq scholarship. Received 4 awards and / or homage. Already coordinated 8 research projects. One of them being PITE JP / FAPESP / Unifran of technological innovation in partnership with company with the aim of developing two drugs against neglected Chagas and schistosomiasis diseases. Participates in the project "Natural Products from Brazilian Marine Ascidians for Tropical Neglected Diseases, Science without Borders recently approved by CNPq. He works in the area of Chemistry of Natural Products and Pharmacy, with emphasis on synthesis, isolation and biological activity of lignans and neolignans, as well as obtaining nanoparticle formulations. He participates as a collaborating professor of the Thematic Project FAPESP USP / Unifran. In his professional activities, he interacted with over 200 collaborators in co-authoring of scientific works. He has been Vice-coordinator of the Graduate Program in Sciences (Master's and Doctorate) for 3 terms, now a member of the Institutional Evaluation Committee of PIBIC Scholarships, PIBITI and PIBIC-EM of the University of Franca and Coordinator of the Institutional Scholarship Program of CNPq PIBITI. It has passed the patent against Erectile Dysfunction in the USA, Japan and Europe. Licensed the Contra Contra patent for the companies Vlli Farm Mercantil and NPA for the production of medicine against DE. Established a partnership with the company Fauna & Flora, Syrian-Lebanese Institute for Teaching and Research and Ekobè do Brasil as a scientific consultant. Leader of the CNPq Group Search for new Drugs from Natural Sources. (Fonte: Currículo Lattes)

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Acoplamento oxidativo Analgésicos Anti-infecciosos Anti-inflamatórios Antiparasitários Bioatividade Ciências Exatas e da Terra Ciências da Saúde Cubebina Doença de Chagas Ensaio clínico Esquistossomicidas Esquistossomose Farmácia Farmacognosia Fármacos Farmacotecnia Hinoquinina Infecção endodôntica Lignanas Mycobacterium Nanopartículas Neolignanas Patentes Piper cubeba Piper Piperaceae Portadores de fármacos Produtos naturais Química Orgânica Química de produtos naturais Química Resultado do tratamento Schistosoma mansoni Schistosoma Sistemas de liberação de medicamentos Tripanossomicidas Trypanosoma cruzi
Patente(s) depositada(s)

PROCESS TO OBTAIN DIBENZYLBUTYROLACTONIC LIGNANS; PROCESS TO OBTAIN SYNTHETIC DERIVATIVES FROM LIGNANES BEARING ANTI-CHAGAS CHEMOPROPHYLACTIC AND THERAPEUTICAL ACTIVITIES DE2003635980 - Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP). Márcio Luís Andrade e Silva ; Sérgio de Albuquerque ; Gustavo Henrique Bianco de Souza ; Jairo Kenupp Bastos ; Rosângela Silva - 25 de março de 2003

PROCESSO DE OBTENÇÃO DE LIGNANAS DIBENZILBUTIROLACTÔNICAS, PROCESSO DE OBTENÇÃO DE DERIVADOS SINTÉTICOS DE LIGNANAS OSTENTANDO ATIVIDADES QUIMIOPROFILÁTICA E TERAPÊUTICA ANTICHAGÁSICA PI0201237-5 - Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP). Márcio Luís Andrade e Silva ; Sérgio de Albuquerque ; Gustavo Henrique Bianco de Souza ; Jairo Kenupp Bastos ; Rosângela Silva - 25 de março de 2002

PROCESSO DE OBTENÇÃO DE LIGNANAS DIBENZILBUTIROLACTÔNICAS, TETRAHIDROFURÂNICAS E DE SEUS DERIVADOS SINTÉTICOS E SEMI-SINTÉTICOS, SUAS ATIVIDADES ANALGÉSICA E ANTIINFLAMATÓRIA, FORMULAÇÕES TÓPICAS E/OU SISTÊMICAS CONTENDO TAIS LIGNANAS E RESPECTIVO MÉTODO TERAPÊUTICO PI0501542-1 - Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP). Márcio Luís Andrade e Silva ; Jairo Kenupp Bastos ; Paulo Marcos Donate ; Sergio de Albuquerque ; Rosangela da Silva - 28 de abril de 2005

PROCESSO DE OBTENÇÃO DE DERIVADOS SINTÉTICOS E SEMI-SINTÉTICOS DE LIGNANAS, SUAS ATIVIDADES ANTIPARASITÁRIAS E RESPECTIVAS FORMULAÇÕES FARMACÊUTICAS, ENGLOBANDO O MÉTODO TERAPÊUTICO UTILIZANDO TAIS LIGNANAS NO TRATAMENTO DE PARASITOSES PI0503951-7 - Acef S/A; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP). Márcio Luís Andrade e Silva ; Rosângela da Silva ; Vanderlei Rodrigues ; Olavo dos Santos Pereira Júnior ; Ademar Alves da Silva Filho ; Paulo Marcos Donate ; Sérgio de Albuquerque ; Jairo Kenupp Bastos - 15 de julho de 2005

PROCESS TO OBTAIN DIBENZYLBUTYROLACTONIC LIGNANS; PROCESS TO OBTAIN SYNTHETIC DERIVATIVES FROM LIGNANES BEARING ANTI-CHAGAS CHEMOPROPHYLACTIC AND THERAPEUTICAL ACTIVITIES US10/508,875 - Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP). Márcio Luís Andrade e Silva ; Sérgio de Albuquerque ; Gustavo Henrique Bianco de Souza ; Jairo Kenupp Bastos ; Rosângela Silva - 25 de março de 2003

PROCESS TO OBTAIN DIBENZYLBUTYROLACTONIC, TETRAHYDROFURANIC LIGNANS AND THEIR SYNTHETIC AND SEMI-SYNTHETIC DERIVATIVES, THEIR ANALGESIC AND ANTI-INFLAMMATORY ACTIVITIES, TOPICAL AND/OR SYSTEMIC FORMULATIONS CONTAINING SAID LIGNANS AND THEIR RESPECTIVE THERAPEUTIC METHOD US11/912,645 - Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP). Márcio Luís Andrade e Silva ; Jairo Kenupp Bastos ; Paulo Marcos Donate ; Sergio de Albuquerque ; Rosangela da Silva - 28 de abril de 2006

PROCESS TO OBTAIN SYNTHETIC AND SEMI-SYNTHETIC LIGNAN DERIVATIVES, THEIR ANTIPARASITIC ACTIVITIES AND CORRESPONDING PHARMACEUTICAL FORMULATIONS, INCLUDING THE THERAPEUTIC METHOD USING SAID LIGNAN FOR THE TREATMENT OF PARASITOSIS  US11/995,789 - Acef S/A; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP). Márcio Luís Andrade e Silva ; Rosângela da Silva ; Vanderlei Rodrigues ; Olavo dos Santos Pereira Júnior ; Ademar Alves da Silva Filho ; Paulo Marcos Donate ; Sérgio de Albuquerque ; Jairo Kenupp Bastos - 14 de julho de 2006

PROCESS TO OBTAIN DIBENZYLBUTYROLACTONIC LIGNANS; PROCESS TO OBTAIN SYNTHETIC DERIVATIVES FROM LIGNANES BEARING ANTI-CHAGAS CHEMOPROPHYLACTIC AND THERAPEUTICAL ACTIVITIES US11/951,460 - Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP). Márcio Luís Andrade e Silva ; Sérgio de Albuquerque ; Gustavo Henrique Bianco de Souza ; Jairo Kenupp Bastos ; Rosângela Silva - 06 de dezembro de 2007

PROCESS TO OBTAIN DIBENZYLBUTYROLACTONIC LIGNANS; PROCESS TO OBTAIN SYNTHETIC DERIVATIVES FROM LIGNANES BEARING ANTI-CHAGAS CHEMOPROPHYLACTIC AND THERAPEUTICAL ACTIVITIES EP20030709465 - Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP). Márcio Luís Andrade e Silva ; Sérgio de Albuquerque ; Gustavo Henrique Bianco de Souza ; Jairo Kenupp Bastos ; Rosângela Silva - 25 de março de 2003

PROCESS TO OBTAIN DIBENZYLBUTYROLACTONIC, TETRAHYDROFURANIC LIGNANS AND THEIR SYNTHETIC AND SEMI-SYNTHETIC DERIVATIVES, THEIR ANALGESIC AND ANTI-INFLAMMATORY ACTIVITIES, TOPICAL AND/OR SYSTEMIC FORMULATIONS CONTAINING SAID LIGNANS AND THEIR RESPECTIVE THERAPEUTIC METHOD EP20060721642 - Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP). Márcio Luís Andrade e Silva ; Jairo Kenupp Bastos ; Paulo Marcos Donate ; Sergio de Albuquerque ; Rosangela da Silva - 28 de abril de 2006

PROCESS TO OBTAIN SYNTHETIC AND SEMI-SYNTHETIC LIGNAN DERIVATIVES, THEIR ANTIPARASITIC ACTIVITIES AND CORRESPONDING PHARMACEUTICAL FORMULATIONS, INCLUDING THE THERAPEUTIC METHOD USING SAID LIGNAN FOR THE TREATMENT OF PARASITOSIS  EP20060761026 - Acef S/A; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP). Márcio Luís Andrade e Silva ; Rosângela da Silva ; Vanderlei Rodrigues ; Olavo dos Santos Pereira Júnior ; Ademar Alves da Silva Filho ; Paulo Marcos Donate ; Sérgio de Albuquerque ; Jairo Kenupp Bastos - 14 de julho de 2006

PROCESS TO OBTAIN DIBENZYLBUTYROLACTONIC LIGNANS; PROCESS TO OBTAIN SYNTHETIC DERIVATIVES FROM LIGNANES BEARING ANTI-CHAGAS CHEMOPROPHYLACTIC AND THERAPEUTICAL ACTIVITIES JP2011098968 - Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP). Márcio Luís Andrade e Silva ; Sérgio de Albuquerque ; Gustavo Henrique Bianco de Souza ; Jairo Kenupp Bastos ; Rosângela Silva - 06 de dezembro de 2007

PROCESS TO OBTAIN DIBENZYLBUTYROLACTONIC LIGNANS; PROCESS TO OBTAIN SYNTHETIC DERIVATIVES FROM LIGNANES BEARING ANTI-CHAGAS CHEMOPROPHYLACTIC AND THERAPEUTICAL ACTIVITIES PCT/BR2003/000045 - Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP). Márcio Luís Andrade e Silva ; Sérgio de Albuquerque ; Gustavo Henrique Bianco de Souza ; Jairo Kenupp Bastos ; Rosângela Silva - 25 de março de 2003

PROCESS TO OBTAIN DIBENZYLBUTYROLACTONIC, TETRAHYDROFURANIC LIGNANS AND THEIR SYNTHETIC AND SEMI-SYNTHETIC DERIVATIVES, THEIR ANALGESIC AND ANTI-INFLAMMATORY ACTIVITIES, TOPICAL AND/OR SYSTEMIC FORMULATIONS CONTAINING SAID LIGNANS AND THEIR RESPECTIVE THERAPEUTIC METHOD PCT/BR2006/000084 - Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP). Márcio Luís Andrade e Silva ; Jairo Kenupp Bastos ; Paulo Marcos Donate ; Sergio de Albuquerque ; Rosangela da Silva - 28 de abril de 2006

PROCESS TO OBTAIN SYNTHETIC AND SEMI-SYNTHETIC LIGNAN DERIVATIVES, THEIR ANTIPARASITIC ACTIVITIES AND CORRESPONDING PHARMACEUTICAL FORMULATIONS, INCLUDING THE THERAPEUTIC METHOD USING SAID LIGNAN FOR THE TREATMENT OF PARASITOSIS  PCT/BR2006/000144 - Acef S/A; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP). Márcio Luís Andrade e Silva ; Rosângela da Silva ; Vanderlei Rodrigues ; Olavo dos Santos Pereira Júnior ; Ademar Alves da Silva Filho ; Paulo Marcos Donate ; Sérgio de Albuquerque ; Jairo Kenupp Bastos - 14 de julho de 2006

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