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Evaluation of Two Quantitative Analysis Methods of Optical Coherence Tomography for Detection of Enamel Demineralization and Comparison With Microhardness

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Autor(es):
Cara, Ana C. B. [1] ; Zezell, Denise M. [1] ; Ana, Patricia A. [2] ; Maldonado, Edison P. [1] ; Freitas, Anderson Z. [1]
Número total de Autores: 5
Afiliação do(s) autor(es):
[1] Inst Pesquisas Energet Nucl, BR-05508000 Sao Paulo - Brazil
[2] Univ Fed ABC, BR-09210180 Santo Andre, SP - Brazil
Número total de Afiliações: 2
Tipo de documento: Artigo Científico
Fonte: Lasers in Surgery and Medicine; v. 46, n. 9, p. 666-671, NOV 2014.
Citações Web of Science: 15
Resumo

Background and ObjectiveWe aimed to evaluate in the same study two quantitative methods for quantification of incipient caries in human dental enamel by using optical coherence tomography (OCT): the optical attenuation coefficient and the area under the A-scan signal, and to compare their results with those obtained from microhardness analysis. Study Design/Materials and MethodsOne hundred and sixty samples were obtained from 40 sound human third molars, which had their crowns sectioned. Simulated caries were created by a pH cycling method. OCT measurements were performed on the samples, before and after the induced demineralization. We determined the total optical attenuation coefficient from the OCT signal in each site and evaluated the sensitivity and specificity of this approach to the detection of the demineralization. Also, the areas under the OCT curves (AUC-OCT) and those from sectional microhardness tests (AUC-MH) were compared. ResultsBoth the analysis of the optical attenuation coefficient and the AUC-OCT were adequate to efficiently distinguish sound and demineralized samples with sensitivity of 0.93 and specificity of 0.96. The AUC-MH and the AUC-OCT data presented linear relationship and correlation of 0.99. ConclusionBoth methods for signal analysis from OCT allowed detection of demineralization with good performance. The AUC-OCT approach enables obtaining a linear relation with the microhardness results, for a quantitative assessment of mineral loss in human teeth. Lasers Surg. Med. 46:666-671, 2014. (c) 2014 Wiley Periodicals, Inc. (AU)

Processo FAPESP: 10/03123-8 - Avaliação do processo de desenvolvimento de desmineralização em esmalte dental utilizando a técnica de tomografia por coerência óptica
Beneficiário:Ana Claudia Ballet de Cara
Linha de fomento: Bolsas no Brasil - Mestrado
Processo FAPESP: 05/51689-2 - Centro de Pesquisa em Óptica e Fotônica - UNICAMP (CEPOF-UNICAMP)
Beneficiário:Hugo Luis Fragnito
Linha de fomento: Auxílio à Pesquisa - Centros de Pesquisa, Inovação e Difusão - CEPIDs