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(Referência obtida automaticamente do Web of Science, por meio da informação sobre o financiamento pela FAPESP e o número do processo correspondente, incluída na publicação pelos autores.)

Correlation Between Impulsivity and Executive Function in Patients With Parkinson Disease Experiencing Depression and Anxiety Symptoms

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Autor(es):
Fonoff, Fernanda Colucci [1] ; Fonoff, Erich Talamoni [2] ; Barbosa, Egberto Reis [3] ; Quaranta, Thais [1] ; Machado, Rachael Brant [3] ; de Andrade, Daniel Ciampi [3] ; Teixeira, Manoel Jacobsen [2] ; Fuentes, Daniel [1]
Número total de Autores: 8
Afiliação do(s) autor(es):
[1] Univ Sao Paulo, Sch Med, Inst Psychiat, LINEU, Sao Paulo - Brazil
[2] Univ Sao Paulo, Sch Med, Dept Neurol, Div Funct Neurosurg, Sao Paulo - Brazil
[3] Univ Sao Paulo, Sch Med, Dept Neurol, Sao Paulo - Brazil
Número total de Afiliações: 3
Tipo de documento: Artigo Científico
Fonte: JOURNAL OF GERIATRIC PSYCHIATRY AND NEUROLOGY; v. 28, n. 1, p. 49-56, MAR 2015.
Citações Web of Science: 10
Resumo

Background:Depression and anxiety are comorbidities often associated with Parkinson disease (PD). Recent studies debate on how affective disorders can influence the cognition of patients with PD. This study sought to investigate how depression and anxiety affect specific executive functions and impulsivity traits in these patients. Methods:Twenty-eight patients with advanced PD and 28 closely matched healthy volunteers (HV) were assessed for depressive and anxiety symptoms, impulsivity, executive function and control attention and behavioral response. Results:Compared to the HV group, the PD group showed significantly higher perseverative responses and slowness to adapt to changes in environmental stimuli and longer reaction time for inter-stimulus interval change. Depression symptoms were significantly correlated to motor impulsivity score and total Barratt Impulsiveness Scale (BIS -11) score. Moreover, there was also significant correlation between anxiety symptoms and attentional impulsivity score and total BIS-11 score. Correlation analysis between impulsivity and control attention indicated a positive correlation in commission and a negative correlation in reaction time and detectability in the PD group. Conclusions:The present results suggest that depression and anxiety were highly correlated to impulsivity but not to executive functions changes in these PD patients. (AU)

Processo FAPESP: 11/08529-5 - Estudo controlado e duplamente encoberto sobre o efeito do ozônio aplicado por endoscopia espinhal no tratamento da síndrome dolorosa pós-laminectomia: análise na dor neuropática e não neuropática e sua correlação com o nível de citocinas epidurais
Beneficiário:Erich Talamoni Fonoff
Linha de fomento: Auxílio à Pesquisa - Regular